Focal myocarditis, an unusual imitator: Case report and short literature review DOI Creative Commons

Nikola Jovanovic,

Nikola Jovanovic

Srpski arhiv za celokupno lekarstvo, Journal Year: 2023, Volume and Issue: 151(7-8), P. 457 - 461

Published: Jan. 1, 2023

Introduction. Acute myocarditis is a serious inflammatory condition of the myocardium. Clinically, symptoms may differ from case to case, and as such can pose significant diagnostic dilemma. Here we present acute focal with markedly elevated troponins, in which diagnosis was finally made using cardiac magnetic resonance (CMR). Case outline. A male patient, 26-year-old, without cardiovascular risk factors presented severe chest pain, diaphoresis, pallor, dyspnea. Blood pressure 160/110 mmHg, electrocardiogram (ECG) showed ST-segment elevation inferior leads. In laboratory there an extreme Troponin. Inferior-posterior-lateral STEMI suspected, initial treatment given according that suspicion. The patient then sent catheterization for further evaluation, absence coronary artery disease. working myocardial infarction non-obstructive arteries (MINOCA) established. To distinguish MINOCA other causes injury CMR done, its finding consistent inferolateral localization. Further consisted beta blockers, angiotensin-converting-enzyme inhibitors avoidance strenuous activity next six months. fully recovered had no complications ECG only showing flat T-wave D3 lead. Conclusion. Focal unusual manifestation disease confuse physicians, especially if it occurs along markers ST-elevation, but young any known comorbidity, this must be considered. Here, useful tool.

Language: Английский

Age-period-cohort analysis of gallbladder and biliary diseases epidemiological trends from 1990 to 2021 and forecasts for 2035: a systematic analysis from the global burden of disease study 2021 DOI Creative Commons
Mingming He,

Ruru Gu,

Xin Huang

et al.

BMC Gastroenterology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 8, 2025

Gallbladder and biliary diseases (GABD) represent prevalent disorders of the digestive system. Data on age-standardized incidence rate (ASIR), mortality (ASMR), disability-adjusted life years (DALYs) (ASDR) were extracted from Global Burden Disease (GBD) 2021 study. The estimated annual percentage change (EAPC) was utilized to quantify temporal trends in GABD. Age-period-cohort analysis conducted determine effects attributable age, period, birth cohort. Additionally, we projected global 2035. Globally, GABD incident cases, DALYs increased by 60.11%, 71.71%, 56.90%, respectively. However, all corresponding rates (ASRs) demonstrated overall downward with changes -0.32 (-0.38 -0.26), -0.95 (-1.08 -0.83), − 0.69 (-0.74 -0.65), number cases higher females than males across age groups. effect indicated that older individuals had age-specific death rates. Both period cohort showed declining risk mortality. ASIR ASMR are continue decreasing over next 15 years. pose a significant public health challenge, particularly affecting women elderly population. Consequently, implementation effective interventions mitigate burden is paramount importance.

Language: Английский

Citations

2
Analysis of the global burden of ovarian cancer in adolescents DOI Creative Commons

Mengting Che,

Rutie Yin

International Journal of Gynecological Cancer, Journal Year: 2025, Volume and Issue: unknown, P. 101620 - 101620

Published: Jan. 1, 2025

Ovarian cancer is the most prevalent gynecologic malignancy in adolescents, predominantly characterized by non-epithelial cancer. We aim to analyze epidemiological characteristics of ovarian various regions and countries within this specific population. This a cross-sectional study using data from Global Burden Disease 2021 study, which included adolescents with aged 15 24 years 204 territories 1990 2021. retrieved on incidence, mortality, disability-adjusted life years, calculated estimated annual percentage changes assess temporal trends. In addition, we explored relationship between disease burden Socio-demographic Index performed decomposition analysis. Globally, 2021, for among were reported as 11,087 (95% CI 8893-12,899), 1573 1249-1832), 115,075 91,622-134,050), respectively, all corresponding age-standardized rates showing increasing trends Among 5 regions, middle region exhibited highest incidence rate (2.27, 95% 1.75-2.66), while mortality significant increase was low-middle region. Furthermore, out 21 geographical Southeast Asia (4.48, 3.00-6.12), Central Latin America had (0.42, 0.36-0.49). Andean greatest burden, Australasia decrease. The continues rise globally, particularly moderate low economic development. Enhancing equitable allocation health care resources facilitate early diagnosis treatment essential future research strategies.

Language: Английский

Citations

1
Global, regional and national epidemiology of myocarditis: health inequalities, risk factors and forecasted burden based on the Global Burden of Disease Study 2021 DOI
Changjun Li, Kun Xu,

Antao Du

et al.

Heart, Journal Year: 2025, Volume and Issue: unknown, P. heartjnl - 325523

Published: April 17, 2025

Abstract Background Myocarditis is a global epidemic that causes various medical conditions associated with an increased incidence and death numbers. This study aimed to investigate the trends in myocarditis-associated incidence, mortality, disability-adjusted life-years (DALYs) health inequalities, risk factors, predict disease burden, thereby mitigating hazards of myocarditis. Methods was modelling used data from Global Burden Diseases 2021, which myocarditis included analysis. Incidence, death, DALYs, age-standardised rate (ASIR), mortality (ASMR), DALYs (ASDR), cases change, corresponding estimated annual percentage change (EAPC), Slope Inequality Index (SII) Concentration were analysed. Results From 1990 by 66.88% 45.94%, respectively. The all five sociodemographic index (SDI) regions. Among SDI regions, High region had highest ASIR least ASMR ASDR 2021. Regionally, Central Asia largest increase EAPC ASIR, ASDR. 204 countries, Japan 2021 Romania Between SII for have shown declining trends. extreme temperatures major contributors burden during 1990–2021. projections suggested myocarditis-related number new would over next 15 years. There may be upward people 15+of 40+of number. Conclusions increasing challenge rising death. Management remains challenge. different age groups continue grow Therefore, measures should taken target factors high-risk groups.

Language: Английский

Citations

1
Global burden of myocarditis in youth and middle age (1990-2019): A systematic analysis of the disease burden and thirty-year forecast DOI
Yayun Zhang,

Lu Feng,

Zixiong Zhu

et al.

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(9), P. 102735 - 102735

Published: June 29, 2024

Language: Английский

Citations

6
Characterization of Brighton Collaboration criteria for myocarditis and pericarditis following COVID-19 vaccine in Korean adolescents DOI
Jue Seong Lee, HyoSug Choi, Seung Hwan Shin

et al.

Vaccine, Journal Year: 2024, Volume and Issue: 42(14), P. 3333 - 3336

Published: April 11, 2024

Language: Английский

Citations

5
Global burden of colorectal cancer attributable to metabolic risks from 1990 to 2021, with projections of mortality to 2035 DOI Creative Commons
Mingming He,

Ruru Gu,

Xin Huang

et al.

International Journal of Colorectal Disease, Journal Year: 2025, Volume and Issue: 40(1)

Published: Feb. 19, 2025

The global burden of colorectal cancer (CRC) attributable to metabolic risk factors is increasing. It crucial analyze the epidemiological patterns CRC and predict future trends. Detailed data on mortality disability-adjusted life years (DALYs) were extracted for this study using from Global Burden Diseases (GBD) 2021 assess 1990 by global, regional, national, sociodemographic index (SDI) regions quantify time trend estimated annual percentage change (EAPC). Bayesian age-period-cohort (BAPC) models projected 2022 2035. number deaths due increased 70,916 in 172,993 2021, a 2.4-fold increase. DALYs high body mass (BMI) fasting plasma glucose (FPG) significantly at level 2021. In GBD with highest age-standardized rate (ASMR) BMI FPG Central Europe. ASMR among males expected increase are Reducing levels critically needed.

Language: Английский

Citations

0
Global, regional, and national burden of elderly myocarditis (1992–2021) and projections of future disease burden trends DOI Creative Commons
Wei Wang, Xiaofeng Chen

Aging Clinical and Experimental Research, Journal Year: 2025, Volume and Issue: 37(1)

Published: March 24, 2025

Abstract Objective Geriatric myocarditis represents a significant public health concern, directly influencing overall and potentially leading to various cardiac diseases. This study seeks quantify the burden of geriatric over three decades (1992–2021) provide forecasts for future disease burden. Methods Data on from 1992 2021 was obtained Global Burden Disease study, offering insights into incidence condition, categorized by gender. The Joinpoint regression model utilized identify shifts in epidemiological trends, while decomposition analysis helped underlying factors contributing these trends. To project incidence, deaths DALYs (Disability-Adjusted Life Years), Norpred Bayesian Age-Period-Cohort (BAPC) models were employed. Results In 2021, global ASIR (per 100,000) elderly 47.57 (27.52–73.08), with 505,147 (292,319–774,561) cases. Age-standardized deaths(per 2.07 (1.55–2.51), totaling 20,718 (15,525–25,085) deaths, age-standardized DALYs(per 29.77 (22.60–35.81), 308,101 (234,226–370,674) DALYs. Greenland, Canada, Austria had highest ASIR(per 100,000), Romania, Kazakhstan, Croatia Guyana 100,000). Regression revealed recent upward trend after previous decline, consistent across genders SDI regions. Deaths showed declining trends globally, though male recently increased. Decomposition identified population growth aging as key drivers increased cases, Based nordpred model, 2045, is predicted be 47.27, 1,005,593 2.02, 48,501 26.21, 595,694 BAPC predicts 51.82, 1,091,195 3.67, 87,145 49.09, 1,084,738 Conclusion As decline compared 1992; however, has been identified. Considering ongoing growth, number cases among anticipated increase.

Language: Английский

Citations

0
Epidemiological Analysis of the Decline of Myocarditis Burden — China, 1992–2021 DOI
Shengnan Wang,

Xiangfeng Zhu,

Yanwu Nie

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 7(15), P. 508 - 513

Published: Jan. 1, 2025

Myocarditis is a prevalent cardiovascular condition that can lead to severe complications. The number of patients with myocarditis, new cases, and deaths in China has been on an upward trend over the years, causing certain disease burden. overall burden myocarditis downward trend; however, age-standardized mortality rate (ASMR) disability-adjusted life years (DALYs) remain higher than global average. incidence (ASIR), ASMR DALYs were men women. Individuals younger 5 or older 70 period from 2002-2016, birth cohort earlier 1957 identified as risk factors for myocarditis-related mortality. We should still prioritize prevention treatment myocarditis. It recommended primary secondary efforts focus individuals males, emphasis proactive health education management.

Language: Английский

Citations

0
Myocarditis: an increasing global health challenge! DOI
Massimo Imazio

Heart, Journal Year: 2025, Volume and Issue: unknown, P. heartjnl - 326105

Published: May 10, 2025

Language: Английский

Citations

0
Ivermectin ameliorates acute myocarditis via the inhibition of importin-mediated nuclear translocation of NF-κB/p65 DOI

Xu Gao,

Yunling Xuan, Zhou Zhou

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 133, P. 112073 - 112073

Published: April 17, 2024

Language: Английский

Citations

3