Prevalence of participation of Brazilian aged people in Advanced Activities of Daily Living and associated factors DOI Creative Commons
Vanessa de Barros e Silva Mazer, Rafael da Silveira Moreira, Kênio Costa de Lima

et al.

Revista Brasileira de Epidemiologia, Journal Year: 2024, Volume and Issue: 27

Published: Jan. 1, 2024

ABSTRACT Objective: To estimate the prevalence of participation aged Brazilians in Advanced Activities Daily Living and associated factors. Methods: Cross-sectional study developed with secondary data from National Health Survey. Aged people (60 years old or older) were included. The dependent variable consisted questions Survey regarding performance Living, related to work, leisure, social participation. Descriptive analysis, Rao-Scott test, standardized residual analysis performed. Effect measures calculated using simple multiple multinominal logistic regression models. Results: majority Brazilian have low Living. males, between 60 69 old, white, Southeast, South Central-West regions, higher educational levels, absence chronic diseases, monthly alcohol consumption, regular physical activity, frequent intake vegetables, use glasses independence when moving, more likely perform Conclusion: These results reinforce significant influence demographic, socioeconomic, clinical factors, linked lifestyle intrinsic capacity execution In a broader sense, such discoveries can strengthen public policies for active healthy aging.

Language: Английский

Triglyceride-glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study DOI Creative Commons
Yan‐Shen Shan, Qingyang Liu, Tianshu Gao

et al.

BMC Endocrine Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 26, 2025

Insulin resistance (IR) is often present in diabetes, which imposes a heavy burden on the prevention and treatment of diabetes. Triglyceride glucose index (TyG) simple, reliable reproducible detecting IR, has great advantages predicting risk The aim this study was to analyze potential association between TyG diabetes Chinese middle-aged older adults using prospective cohort design. This used longitudinal data from five waves China Health Retirement Longitudinal Study (CHARLS) conducted 2011, 2013, 2015, 2018, 2020, involving 5886 participants. We Cox proportional regression modeling investigate new-onset decision tree analysis identify high-risk groups for Finally, ROC curves were applied order construct predictive model A total 1054 (17.9%) participants developed throughout 9-year follow-up. Our utilized multivariate found significant correlation risk. also revealed nonlinear relationship risk.Receiver Operating Characteristic(ROC) curve showed that Area under curve(AUC) area 0.652 (P < 0.05). can be as factor elderly population China. In addition, there Improving insulin by regulating lipid metabolism plays an important role primary

Language: Английский

Citations

0
Caregiver Burden and Associated Factors Among Informal Caregivers of Hospitalized Elderly Patients in China: A Latent Profile Analysis DOI Creative Commons

Hui Lv,

Shujie Yang,

Yuxi Zhang

et al.

Risk Management and Healthcare Policy, Journal Year: 2025, Volume and Issue: Volume 18, P. 547 - 559

Published: Feb. 1, 2025

Caregiver burden is a critical issue in healthcare, particularly among informal caregivers of hospitalized elderly patients, as it can significantly impact both the caregivers' well-being and quality patient care. This study aims to identify latent profiles caregiver patients factors associated with burden. 506 pairs their were interviewed using Sociodemographic questionnaire, Burden Inventory, Perceived Social Support Scale, Generalized Anxiety Disorder, Barthel Index. Latent profile analysis identified profiles, multinomial logistic regression determined factors. The was classified into three profiles: low (49.01%), moderate (41.90%), high (9.09%). Individual (older age, economic stress, poor self-rated health, caregiving ability profound anxiety) situational (inadequate social support, caring for limited ADL) level (P<0.05). These showed different characteristics dimensions findings provide basis developing targeted interventions alleviate enhance care quality.

Language: Английский

Citations

0
Comorbidity Patterns and Influencing Factors in Elderly Chronic Disease Patients: A Five-Year Retrospective Study DOI Creative Commons

Yugao Wu,

Rongyue Li,

Guanghui Guo

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Abstract Background: This study aims to analyze the comorbidity patterns of chronic diseases in elderly patients aged 65 and above at Panzhihua Central Hospital their relationships with gender age, revealing strength associations between common diseases, thereby providing data support for clinical management public health strategies. Methods: retrospective analyzed medical records 88,742 hospitalized from January 2019 December 2023. Patient data, including gender, primary diagnosis, other disease diagnoses, were collected through hospital's information system. Diseases classified statistically according International Classification Diseases, 10th Revision (ICD-10). The among 13 analyzed. Results: Hypertension, diabetes, coronary heart are most patients. three-way pattern is HTN + DM CA, a prevalence 41.05%. Gender age have significant impacts on patterns. Chronic obstructive pulmonary (COPD) failure (HF) more male patients, while gastrointestinal renal predominant females. As increases, rate cardiovascular neurological rises significantly, particularly individuals 80 above. Hypertension shows association like diabetes disease, relationship atrial fibrillation strong, suggesting potential shared pathological mechanism these diseases. Conclusions: there high degree significantly influence patterns, strong findings provide important evidence population, development personalized strategies based characteristics optimize allocation resources.

Language: Английский

Citations

0
The characteristics of adverse reactions of three anti-prostate cancer drugs based on Vigiaccess database and bibliometric analysis DOI Creative Commons
Jianqing Wang, Jia You, Weixing Huang

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: March 27, 2025

Background Androgen antagonists, including apalutamide, darolutamide, and enzalutamide, play a crucial role in the treatment of prostate cancer. This research evaluated adverse drug reactions (ADRs) associated with use these androgen antagonists as reported by World Health Organization (WHO). Additionally, it compared reaction (ADR) profiles three drugs to identify which one presents lowest risk for individualized patient use. Methods study employed retrospective descriptive analysis design. We collected event reports marketed from WHO-VigiAccess analyzed them combination bibliometric analysis. calculated percentage each compare similarities differences among drugs. Results A total 172,020 events (AEs) were VigiAccess at time this study. Our findings show apalutamide causes most endocrine disorders. Darolutamide has highest rate blood lymphatic disorders, while enzalutamide nervous system The ten common ADRs identified fatigue, rash, death, hot flush, diarrhoea, asthenia, nausea, dizziness, arthralgia, decreased appetite. Conclusion utilizes real data WHO-VigiAccess, offers valuable insights clinical reference. On hand, we confirm both existing potential effects antagonists. other possible future directions, thereby supporting case more scientific treatment.

Language: Английский

Citations

0
Impact of medical-nursing combined policy pilot on hospitalization frequency of middle-aged and older patients with chronic diseases: a quasi-experimental study based on China Health and Retirement Longitudinal Study DOI Creative Commons
Penghao Fan, Hongying Li, Hongyan Xu

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Oct. 11, 2024

Background To address the growing burden of older adult care, Chinese government has introduced a policy that integrates medical care with elder launching two batches national pilot projects. A majority population suffers from one or more chronic diseases, many experiencing multiple conditions, necessitating support both and services. Methods Using panel data China Health Retirement Longitudinal Study (CHARLS) spanning 2011 to 2020, this study employs difference-in-difference (DID) model analyze impact integrated medical-nursing on physical health patients diseases. Results The found average annual number hospitalizations for individuals diseases was 0.276. reduced by 0.0405. Additionally, hospitalization rate 0.339, higher than former group. 0.0738 in Conclusion demonstrates implementation significantly improved should promote these policies larger scale, explore various forms provide comprehensive services

Language: Английский

Citations

1
Inhibition of the RXRA-PPARα-FABP4 signaling pathway alleviates vascular cellular aging by an SGLT2 inhibitor in an atherosclerotic mice model DOI
Weiwei Zhang,

Linghuan Wang,

Yujia Wang

et al.

Science China Life Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 29, 2024

Language: Английский

Citations

0
The clinical advantages of making our hospitals older adult friendly. DOI Creative Commons
Adrian Wagg, George Heckman, Melissa Northwood

et al.

Canadian Journal of Cardiology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

0
Wearable equipment-based telemedical management via multiparameter monitoring on cardiovascular outcomes in elderly patients with chronic coronary heart disease: an open-labelled, randomised, controlled trial DOI Creative Commons
Tingting Lu, Ruihua Cao, Yujia Wang

et al.

BMJ Health & Care Informatics, Journal Year: 2024, Volume and Issue: 31(1), P. e101135 - e101135

Published: Dec. 1, 2024

Background The prevalence of chronic coronary heart diseases (CHDs) increases with age in the elderly, which represents one top-ranked causes death and disease burden. Methods This study aimed to investigate management efficiency telemedicine based on remote multiparameter monitoring elderly patients CHD. A total 1248 diagnosed CHD were enrolled. subjects randomly divided into two groups, wearable equipment-based telemedical (WTM) group traditional follow-up (TFM) group. Face-to-face clinical interview at least once every 2 months was required TFM collect medical records. Patients WTM provided equipment complete monitoring, real-time alerts health intervention via virtual consultations medication recommendations. Results mean 71.1 (68.0–82.0) years 71.0 (68.0–81.0) years, respectively‏. After a 12-month management, presented lower occurrence hospitalisation (HR 0.59, 95% CI=0.47 0.73, p<0.0001) major adverse cardiac events 0.60, CI=0.44 0.82, p=0.0012) compared Conclusion could help out-of-hospital reduce incidence rehospitalisation

Language: Английский

Citations

0
Prevalência da participação de pessoas idosas brasileiras em Atividades Avançadas da Vida Diária e fatores associados DOI Creative Commons
Vanessa de Barros e Silva Mazer, Rafael da Silveira Moreira, Kênio Costa de Lima

et al.

Revista Brasileira de Epidemiologia, Journal Year: 2024, Volume and Issue: 27

Published: Jan. 1, 2024

Resumo Objetivo: Estimar a prevalência da participação de pessoas idosas brasileiras em Atividades Avançadas Vida Diária e fatores associados. Métodos: Estudo transversal desenvolvido com dados secundários Pesquisa Nacional Saúde (PNS). Foram incluídas (60 anos ou mais). A variável dependente foi composta pelas questões PNS referentes à realização relacionadas trabalho, lazer social. realizados análise descritiva, teste Rao-Scott resíduo padronizado. As medidas efeito foram calculadas por modelos simples múltiplos regressão logística multinominal. Resultados: maioria das apresenta baixa para as Diária. do sexo masculino, entre 60 69 anos, brancas, regiões Sudeste, Sul Centro-Oeste, níveis educacionais mais elevados, ausência doenças crônicas, consumo mensal álcool, prática atividade física regular, ingestão frequente verduras legumes, uso óculos independência no deslocamento estavam propensas executar Conclusão: Esses resultados reforçam influência significativa dos demográficos, socioeconômicos clínicos ligados ao estilo vida capacidade intrínseca na execução No âmbito amplo, tais descobertas podem fortalecer políticas públicas envelhecimento ativo saudável.

Citations

0
Prevalence of participation of Brazilian aged people in Advanced Activities of Daily Living and associated factors DOI Creative Commons
Vanessa de Barros e Silva Mazer, Rafael da Silveira Moreira, Kênio Costa de Lima

et al.

Revista Brasileira de Epidemiologia, Journal Year: 2024, Volume and Issue: 27

Published: Jan. 1, 2024

ABSTRACT Objective: To estimate the prevalence of participation aged Brazilians in Advanced Activities Daily Living and associated factors. Methods: Cross-sectional study developed with secondary data from National Health Survey. Aged people (60 years old or older) were included. The dependent variable consisted questions Survey regarding performance Living, related to work, leisure, social participation. Descriptive analysis, Rao-Scott test, standardized residual analysis performed. Effect measures calculated using simple multiple multinominal logistic regression models. Results: majority Brazilian have low Living. males, between 60 69 old, white, Southeast, South Central-West regions, higher educational levels, absence chronic diseases, monthly alcohol consumption, regular physical activity, frequent intake vegetables, use glasses independence when moving, more likely perform Conclusion: These results reinforce significant influence demographic, socioeconomic, clinical factors, linked lifestyle intrinsic capacity execution In a broader sense, such discoveries can strengthen public policies for active healthy aging.

Language: Английский

Citations

0