Association between dietary patterns and suicide ideation among depressed adults: Insights from NHANES 2007–2020

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 377, P. 235 - 244

Published: Feb. 21, 2025

Language: Английский

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Association between CAPN-10 gene variant and diabetes mellitus in Nigeria: a review

Egyptian Journal of Medical Human Genetics, Journal Year: 2025, Volume and Issue: 26(1)

Published: Feb. 7, 2025

Abstract Background Type 2 Diabetes Mellitus (T2DM) is a significant global health concern characterised by insulin resistance and chronic hyperglycemia. Genetic factors, particularly variations in the CAPN-10 gene, have been implicated T2DM susceptibility across diverse populations. Aim objective This study aimed to conduct meta-analysis investigate associations of single nucleotide polymorphisms (SNPs) gene with among various populations, focusing specifically on Nigerian cohorts. Materials methods A comprehensive literature search yielded 150 studies, from which 45 met inclusion criteria, encompassing approximately 25,000 individuals, including 10,000 diagnosed T2DM. Statistical analyses assessed association between SNPs (UCSNP-43, UCSNP-19, UCSNP-63) risk. Results was observed for UCSNP-43 (rs3792267) (OR 1.50; 95% CI 1.28–1.75; p < 0.001), urban UCSNP-19 (rs3842570) also showed moderate 1.35; 1.10–1.66; = 0.01), especially South-West Nigeria. No found UCSNP-63 1.15; 0.90–1.45; 0.30). Conclusion The findings indicate that SNPs, contribute emphasising importance genetic screening personalised interventions diabetes management.

Language: Английский

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Assessment of Depression and Its Association With Sleep Quality Among the General Population of Perambalur in Tamil Nadu, India: A Cross-Sectional Analysis

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

Background Sleep quality and depression represent significant public health concerns with complex bidirectional relationships. Despite extensive research in specific populations, comprehensive studies examining their association general populations remain limited, particularly developing regions. This study aimed to assess the prevalence of poor sleep among population Perambalur, Tamil Nadu, examine interrelationship, identify associated sociodemographic behavioral factors influencing this relationship. Additionally, sought analyze impact severity on parameters investigate potential risk affecting both conditions. Methodology A cross-sectional analytical was conducted 650 participants from Perambalur district, India. Data collection involved face-to-face interviews using a structured questionnaire comprising profiles, Pittsburgh Quality Index (PSQI) for assessment, Patient Health Questionnaire-9 (PHQ-9) evaluation. The underwent forward-backward translation pilot testing. categorized PSQI scores (>5 indicating sleep), while classified as minimal (0-4), mild (5-9), moderate (10-14), moderately severe (15-19), (20-27). analysis employed descriptive statistics, chi-square tests, multivariable logistic regression, p<0.05 considered statistically significant. Results population, mean age 35.71±14.70 years, comprised 381 (58.6%) females 269 (41.4%) males. revealed that 385 (59.2%) had depression, 171 (26.3%) 62 (9.5%) 27 (4.2%) five (0.8%) depression. Poor reported by 142 (21.8%) participants. Sleep-related showed 100 (15.4%) experiencing difficulty initiating sleep, 102 (15.7%) reporting midnight awakenings, 34 (5.2%) self-medication. Logistic regression identified self-medication (adjusted odds ratio (AOR)=8.45, 95% CI: 3.12-22.86) severe/severe (AOR=7.92, 3.45-18.19) strongest predictors quality. demonstrated progressive deterioration across levels, increasing 3.2±1.8 11.3±3.2 strong positive correlation observed between PHQ-9 (r=0.65, p<0.001). Conclusion establishes associations quality, highlighting need integrated healthcare approaches. high underscore importance targeted interventions improved access professional services, focusing vulnerable urban rural settings.

Language: Английский

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Association between plant-based diets and depression in older adults with heart disease: the mediating role of sleep disturbances

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 16, 2025

Background Depression is not uncommon among older adults with heart diseases and related to poor prognosis at clinical setting. We aim explore the association between plant-based diets depression in disease further investigate mediating role of sleep disturbances this relationship. Methods A cross-sectional sample 2039 were recruited from 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS). Each individual completed assessments on dietary frequency, depression, quality duration. Plant-based diet index (PDI), healthy (hPDI) unhealthy (uPDI) calculated. Logistic regression models restricted cubic spline curves (RCS) employed relationship disease. Meanwhile, mediation analysis was used roles Results The higher PDI (OR: 0.56, 95% CI: 0.36–0.88) hPDI 0.39, 0.24–0.62), lower risk Conversely, uPDI, 1.76, 1.07–2.92). RCS confirmed a negative linear dose–response PDI, disease, positive trend found uPDI depression. Notably, (Indirect effect: −0.031, mediated proportion: 61%) partially In sex-based subgroup analysis, only associated females. Conclusion This first study suggest significant Sleep plays Optimizing structure improve may help reduce

Language: Английский

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Relationship between oxidative balance score and post-stroke depression: insights from the NHANES 2005–2018 cross-sectional study

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 25, 2024

The Oxidative Balance Score (OBS) represents an integrated measure of oxidative-reductive homeostasis. Despite the established role oxidative stress in development post-stroke depression (PSD), association between OBS and PSD general population remains unclear. This study aims to explore this relationship using data from National Health Nutrition Examination Survey (NHANES) spanning 2005-2018.

Language: Английский

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