Dietary modulation for the hypertension risk group in Koreans: a cross-sectional study

Nutrition & Metabolism, Journal Year: 2025, Volume and Issue: 22(1)

Published: April 10, 2025

Abstract Background Hypertension (HTN) is a critical global health issue, contributing to high morbidity and mortality rates. Representative risk factors for HTN include aging, genetics, obesity, alcohol drinking, smoking, diet. Dietary interventions like the Approaches Stop (DASH) diet plan effectively prevent manage HTN. We intend evaluate influence of eating patterns on HTN, applying multiple factors. Methods For cross-sectional design, study subjects were grouped into four groups: optimal ( n = 7,712), normal 1,220), 3,655), 4,355) according 2022 treatment guidelines Korea. Factor analysis was performed identify major dietary based nutritional data obtained from brief questionnaire, including 17 food items. Finally, we conducted moderation impact score, which determined by genetic variables, body mass index, consumption, smoking status. Results identified three principal (Korean, Western, New diet) in population. Adherence linked lower all models p < 0.001), while Western Korean diets associated with higher some models. In HTN-risk individuals, adherence increased trend whereas showed potential protective 0.059). Conclusions The effect evident high-risk group, where risk, borderline effect. If findings are validated longitudinal investigation, our could serve as basis developing

Language: Английский

Joint Association of Remnant Cholesterol and Body Mass Index with Hypertension: A National Cohort Study in Chinese Adults.

PubMed, Journal Year: 2025, Volume and Issue: 18, P. 1813 - 1825

Published: Jan. 1, 2025

Hypertension, a major global health concern, is closely associated with obesity and lipid abnormalities. Remnant cholesterol (RC), triglyceride-rich lipoprotein component, has been linked to cardiovascular diseases, but its joint impact body mass index (BMI) on hypertension risk remains unclear. We analyzed data from 3805 participants (mean age: 57 years; 44.3% male) in the China Health Retirement Longitudinal Study (CHARLS) 2011-2020. Inclusion criteria were adults aged over 45 years complete blood lipids BMI. Participants baseline or missing covariate excluded. Cox proportional hazard models assessed associations, while mediation analysis explored RC's role BMI-hypertension linkage. Over 9-year follow-up, 590 developed hypertension. Obesity (BMI ≥28.0 kg/m²) high RC levels independently (HR: 2.18; 95% CI: 1.48-3.21 for highest tertile). mediated 7.07% of BMI's effect hypertension, BMI 29.3% effect. This study highlights intertwined roles development. Targeting both factors may enhance prevention strategies.

Language: Английский