Correlation of neutrophil percentage-to-albumin ratio with lung function in American adults: a population study DOI Creative Commons
Xiaolin Zhang, Fan Bai, Haibin Ni

et al.

BMC Pulmonary Medicine, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 21, 2025

Chronic respiratory diseases pose a significant threat to global health, underscoring the urgent need for effective preventative and therapeutic interventions. The neutrophil-to-albumin ratio (NPAR), an emerging biomarker inflammation nutritional status, has shown promising associations with necessitating investigation into its potential predicting lung function decline. This study aimed delineate relationship between NPAR pulmonary within sample of American adult population assess viability as prognostic indicator compromised function. With data available from National Health Nutrition Examination Survey (NHANES) years 2007 2012, 10,055 adults who met exclusion criteria were included in current study. Multivariate linear regression, smoothed curve fitting, subgroup analyses applied evaluate observed indicators. Even after accounting all confounding factors, inverse persisted key indicators, including forced expiratory volume one second (FEV1), vital capacity (FVC), peak flow rate (PEF). association remained robust even factors considered. Subgroup analysis revealed that negative correlation was more pronounced certain demographic groups, such young individuals, males, smokers. also "N-shaped" fractional exhaled nitric oxide (FENO), suggesting may play role promoting airway inflammation. A decline among this research, emphasizing clinical relevance health biomarker, well importance considering systemic management prevention disorders.

Language: Английский

Correlation of neutrophil percentage-to-albumin ratio with lung function in American adults: a population study DOI Creative Commons
Xiaolin Zhang, Fan Bai, Haibin Ni

et al.

BMC Pulmonary Medicine, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 21, 2025

Chronic respiratory diseases pose a significant threat to global health, underscoring the urgent need for effective preventative and therapeutic interventions. The neutrophil-to-albumin ratio (NPAR), an emerging biomarker inflammation nutritional status, has shown promising associations with necessitating investigation into its potential predicting lung function decline. This study aimed delineate relationship between NPAR pulmonary within sample of American adult population assess viability as prognostic indicator compromised function. With data available from National Health Nutrition Examination Survey (NHANES) years 2007 2012, 10,055 adults who met exclusion criteria were included in current study. Multivariate linear regression, smoothed curve fitting, subgroup analyses applied evaluate observed indicators. Even after accounting all confounding factors, inverse persisted key indicators, including forced expiratory volume one second (FEV1), vital capacity (FVC), peak flow rate (PEF). association remained robust even factors considered. Subgroup analysis revealed that negative correlation was more pronounced certain demographic groups, such young individuals, males, smokers. also "N-shaped" fractional exhaled nitric oxide (FENO), suggesting may play role promoting airway inflammation. A decline among this research, emphasizing clinical relevance health biomarker, well importance considering systemic management prevention disorders.

Language: Английский

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