Effect of Caloric Restriction Combined with Probiotic Supplementation on Parameters Related to Weight Loss, Homeostatic, and Hedonic Systems of Food Intake in Adult Men Living with Obesity: Secondary Data from a Randomized, Parallel, Double-Blind, Placebo-Controlled Clinical Trial DOI Creative Commons
Marcus Vinicius Lúcio dos Santos Quaresma,

Glaice Aparecida Lucin,

Camila Moraes Marques

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Abstract We aimed to investigate the effect of CR with probiotic supplementation on weight loss and parameters related homeostatic hedonic systems. It is a randomized, double-blind, parallel, placebo-controlled clinical trial (UTN: U1111-1247-9906). include obese adult males, aged 25 44 years. The established was 30% daily energy expenditure. Probiotic was: two sachets 1 g each 1×10⁹ CFU Lactobacillus acidophilus NCFM, rhamnosus HN001, paracasei Lpc-37, Bifidobacterium lactis HN019. primary outcomes: body composition. Secondary leptin, ghrelin, GLP-1, glucose-dependent insulinotropic polypeptide (GIP), insulin, peptide YY (PYY), adiponectin. Additionally, binge eating, emotional cognitive restraint were assessed by Three-Factor Eating Questionnaire. study includes per protocol analyses (CR + placebo [CRPLA] n = 12 vs. [CRPRO] 13). Body mass (F 65.9; p < 0.001) decreased after 4 weeks (p 0.001). A similar result found for absolute fat 71.0; Leptin levels 13.2; 0.002) 0.001), without group or interaction effect. Moreover, GLP-1 did not change intervention 2.29; 0.114). Likewise, GIP 2.0; 0.148) adiponectin 3.14; 0.053) change. Binge eating reduced 16.5; only in CRPRO 0.018). Emotional 9.44; 0.005), but 0.047). Finally, increased 43.2; CRPLA 0.003) groups. In summary, fat, as well leptin restraint. reductions scores seen group.

Language: Английский

Effects of probiotic supplementation on the anthropometric nutritional status of patients with type 2 Diabetes mellitus: A systematic review and meta-analysis protocol DOI Creative Commons

Dálete Assíria de Souza Ribeiro,

Anny Cristine de Araújo,

Priscila Kelly da Silva Bezerra do Nascimento

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314971 - e0314971

Published: Dec. 6, 2024

Background Diabetes mellitus (DM) is characterized by hyperglycemia due to insufficient insulin production or utilization. Previous studies have shown a relationship between the gut microbiota and DM, driving interest in probiotic supplementation modulate glucose metabolism patients with although exact mechanisms remain unclear. Probiotics can influence metabolic factors improve composition of microbiota, possibly helping reduce weight DM. Objective The objective this review compile analyze most relevant evidence on effects nutritional anthropometric status type 2 (T2DM). Methods Methodological guidelines will be followed accordance Preferred Reporting Items for Systematic Reviews Meta-Analyses statement study has been registered International Prospective Register under reference number CRD42023480243. Studies selected through an active search PubMed, Science Direct, SCOPUS databases using following descriptors: body weight, diseases, according medical subject headings. assessment methodological quality carried out Cochrane Collaboration instrument. risk bias analyzed Revised tool randomized controlled trials (RoB 2). A meta-analysis performed if heterogeneity acceptable justifiable; otherwise, results presented qualitative narrative synthesis. Expected are expected demonstrate improvements parameters such as BMI abdominal waist circumference T2DM, thus providing valuable clinical application.

Language: Английский

Citations

0
Probing the Potency: Probiotics and Prebiotics in Diabetes DOI
R. Preethi, Arunkumar Jayaraman,

N. Unnamalai

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
What’s gut got to do with it? The role of the microbiota and inflammation in the development of adiposity and obesity DOI Open Access
Travis L. Jennings,

Mallory Janquart,

Catherine Washak

et al.

Immunometabolism, Journal Year: 2023, Volume and Issue: 5(3), P. e00029 - e00029

Published: July 1, 2023

Obesity is a complex and heterogeneous disease characterized by increased adiposity, ie, the accumulation of lipids growth adipose tissue. In this mini-review, we explore important role gut microbiota immune system in development adiposity. Dysbiosis leads to permeability barrier bacterial products bloodstream, which triggers metabolic inflammation tissue, muscle, liver. Inflammation these highly organs exacerbates adiposity contributes comorbidities associated with obesity. Studies animal models that manipulate and/or have shown promise treatment

Language: Английский

Citations

1
Effect of Caloric Restriction Combined with Probiotic Supplementation on Parameters Related to Weight Loss, Homeostatic, and Hedonic Systems of Food Intake in Adult Men Living with Obesity: Secondary Data from a Randomized, Parallel, Double-Blind, Placebo-Controlled Clinical Trial DOI Creative Commons
Marcus Vinicius Lúcio dos Santos Quaresma,

Glaice Aparecida Lucin,

Camila Moraes Marques

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Abstract We aimed to investigate the effect of CR with probiotic supplementation on weight loss and parameters related homeostatic hedonic systems. It is a randomized, double-blind, parallel, placebo-controlled clinical trial (UTN: U1111-1247-9906). include obese adult males, aged 25 44 years. The established was 30% daily energy expenditure. Probiotic was: two sachets 1 g each 1×10⁹ CFU Lactobacillus acidophilus NCFM, rhamnosus HN001, paracasei Lpc-37, Bifidobacterium lactis HN019. primary outcomes: body composition. Secondary leptin, ghrelin, GLP-1, glucose-dependent insulinotropic polypeptide (GIP), insulin, peptide YY (PYY), adiponectin. Additionally, binge eating, emotional cognitive restraint were assessed by Three-Factor Eating Questionnaire. study includes per protocol analyses (CR + placebo [CRPLA] n = 12 vs. [CRPRO] 13). Body mass (F 65.9; p < 0.001) decreased after 4 weeks (p 0.001). A similar result found for absolute fat 71.0; Leptin levels 13.2; 0.002) 0.001), without group or interaction effect. Moreover, GLP-1 did not change intervention 2.29; 0.114). Likewise, GIP 2.0; 0.148) adiponectin 3.14; 0.053) change. Binge eating reduced 16.5; only in CRPRO 0.018). Emotional 9.44; 0.005), but 0.047). Finally, increased 43.2; CRPLA 0.003) groups. In summary, fat, as well leptin restraint. reductions scores seen group.

Language: Английский

Citations

0