Associations between life’s essential 8 and femoral neck bone mineral density among adults: A national population-based study DOI Creative Commons

Linjian Liu,

An Zhang,

Xiangjun Xiao

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(36), P. e39540 - e39540

Published: Sept. 6, 2024

Osteoporosis represents a significant public health issue, impacting both outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from National Health Nutrition Examination Survey (NHANES) spanning 2011 to 2018 were analyzed in this cross-sectional analysis, including 9018 subjects following exclusion of individuals lacking BMD or data. The comprising factors such diet, physical activity, smoking status, sleep quality, body mass index, lipid profiles, blood glucose, pressure, was used evaluate health. determined through dual-energy X-ray absorptiometry (DXA). Relationships between scores at femoral neck assessed using linear regression smooth curve fitting techniques. Enhanced linked improved neck. Notably, 10-point increment score associated rise 0.04 g/cm² [β = 0.04, 95% CI: 0.03–0.05]. data indicate strong positive association measured LE8, BMD. These results support development holistic strategies that promote potentially improve density.

Language: Английский

The association between the triglyceride-glucose index and sarcopenia: data from the NHANES 2011–2018 DOI Creative Commons

Jiju Yang,

Cong Liu,

Sihao Zhao

et al.

Lipids in Health and Disease, Journal Year: 2024, Volume and Issue: 23(1)

Published: July 19, 2024

Abstract Background The Triglyceride-glucose (TyG) index is a marker of insulin resistance, but its role in sarcopenia controversial. purpose this study was to investigate the association TyG with sarcopenia. Methods 4030 participants aged 20 years and above were selected from National Health Nutrition Examination Survey for cross sectional study. Weighted logistic regression model used estimate between Threshold effect analysis restricted cubic spline employed describe nonlinear link, interaction tests subgroup analyses performed. Results It found fully adjusted that positively associated (per 1-unit increase index: OR = 1.31, 95%CI: 1.07, 1.60). This further highlighted groups characterized by absence MetS or diabetes, as well vigorous moderate work activity. Furthermore, curve fitting threshold effects indicated relationship, which exhibited turning point at 9.14. Conclusion results Enhancing management resistance could help reduce risk developing

Language: Английский

Citations

11
The association of waist circumference with bone mineral density and risk of osteoporosis in US adult: National health and nutrition examination survey DOI
Runzhou Pan, Rongrong Wang, Yan Zhang

et al.

Bone, Journal Year: 2024, Volume and Issue: 185, P. 117134 - 117134

Published: May 29, 2024

Language: Английский

Citations

9
Correlation between weight-adjusted waist index and coronary heart disease: NHANES 1999–2020 DOI Creative Commons
Yan Liu, Shougang Sun, Qi Zou

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 10, 2025

The weight adjusted waist index (WWI) represents a novel indicator for assessing central obesity. objective of this study is to investigate the association between WWI and coronary heart disease (CHD). data 44,528 participants in total were gathered from NHANES database 1999 2020. calculated as circumference (WC, cm) divided by square root body (kg), CHD was determined based on participants' self-reports. examined using multiple logistic regression analysis, restrictive cubic spline (RCS), receiver operating characteristic (ROC) curve, mediation subgroup interaction analyses. This cross-sectional investigation. A included [50.23% male; mean 10.89 (0.01) cm/√kg]. multivariate analysis revealed that three models, one-standard-deviation increment associated with an increased probability occurrence 2.39 (2.22,2.57),1.47 (1.32,1.65), 1.15 (1.00,1.32) times, respectively. Additionally, RCS indicated linear relationship CHD. ROC results showed discriminatory power superior mass (BMI) WC. Glycated hemoglobin (HbA1c) partially mediated Subgroup analyses confirmed age, systolic blood pressure, diabetes status had significant impact (P <0.05). level has been demonstrated be risk Specifically, increases, becomes higher. On basis, it hypothesized may potentially serve independent factor CAD, thereby highlighting substantial value identification management

Language: Английский

Citations

1
Associations between cadmium exposure and whole-body aging: mediation analysis in the NHANES DOI Creative Commons
Ya Zhang, Mingjiang Liu, Ruijie Xie

et al.

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Aug. 31, 2023

Even though cadmium (Cd) exposure and cellular senescence (telomere length) have been linked in previous studies, composite molecular aging biomarkers are more significant reliable factors to consider when examining the connection between metal health outcomes. The purpose of this research was assess association urinary (U-Cd) whole-body (phenotypic age).Phenotypic age calculated from chronological 9 biomarkers. Multivariate linear regression models, subgroup analysis, smoothing curve fitting were used explore nonlinear relationship U-Cd phenotypic age. Mediation analysis performed mediating effect on smoking age.This study included 10,083 participants with a mean 42.24 years 42.34 years, respectively. In fully adjusted model, there positive [2.13 per 1 ng/g U-Cd, (1.67, 2.58)]. This differed by sex, age, subgroups (P for interaction < 0.05). mediated serum cotinine proportion 23.2%.Our results suggest that high levels Cd associated aging.

Language: Английский

Citations

19
Association of cardiovascular health and periodontitis: a population-based study DOI Creative Commons

Haitao Qu,

Shengnan Zhang

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Feb. 12, 2024

Abstract Background There is a strong association between cardiovascular disease (CVD) and periodontitis. This study utilized the Life Essentials 8 (LE8) score, composite measure of health (CVH), to elucidate relationship CVH Methods Data from 8,649 nationally representative participants in National Health Nutrition Examination Survey (NHANES) were analyzed. The independent variable our was score (a higher indicates better health), dependent presence or absence periodontitis investigated using weighted multivariable logistic regression models restricted cubic spline (RCS). We controlled for potential confounders such as age, sex, race, education, socioeconomic status minimize bias. Results negative total odds After adjusting all covariates, 10-point increase associated with 10% lower [0.90 (0.87, 0.93)]. Participants had 40% compared those CVH. Socioeconomic (education income) modified this ( P interaction < 0.05). Conclusion Our suggests that health, indicated by scores, reduced likelihood among US adults. appears be influenced status, emphasizing need targeted interventions populations status.

Language: Английский

Citations

7
The association between weight-adjusted-waist index and muscle strength in adults: a population-based study DOI Creative Commons

Lihan Xu,

Haojing Zhou

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: July 26, 2024

The relationship between the weight-adjusted-waist index (WWI) and grip strength, a crucial marker in assessing sarcopenia, lacks clarity. We aimed to explore WWI muscle strength across genders.

Language: Английский

Citations

5
The associations of cardiovascular health and all-cause mortality among individuals with depression DOI Creative Commons
Ming‐Qing Li,

Yueqin Huang,

Jie Zhou

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 8, 2025

The association between the recently updated cardiovascular health (CVH) assessment algorithm, Life's Essential 8 (LE8), and all-cause mortality among adults with depression remains unknown. From National Health Nutrition Examination Survey (NHANES) spanning 2005–2018, a cohort of 2,935 individuals diagnosed was identified. Their CVH evaluated through LE8 score system. investigation status utilized connections Death Index up to December 31, 2019. To assess impact on risk, Kaplan-Meier survival analysis Cox proportional hazards models, adjusting for variables related demographics socioeconomic status, were applied. Among participants, those higher levels had significantly lower compared levels. regression analyses demonstrated that each 1-point increase in associated risk [HR = 0.97, 95%CI:0.96–0.98]. inverse persisted across different demographic subgroups. Higher depression. These findings underscore importance comprehensive management as part healthcare strategies people depression, suggesting improving may contribute longer life expectancy this vulnerable population.

Language: Английский

Citations

0
Associations between dietary fatty acids and kidney stones DOI Creative Commons
Ning Tan, Ya Zhang

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 20, 2025

Kidney stones represent a significant global health challenge, with dietary habits playing crucial role in their formation. This study investigates the association between fatty acid intake—specifically saturated (SFA), monounsaturated (MUFA), and polyunsaturated acids (PUFA)—and prevalence of kidney U.S. adult population, aiming to inform potential prevention strategies. Data from National Health Nutrition Examination Survey (NHANES) spanning 2007–2018 were analyzed, including 30,716 participants. Logistic regression models used assess relationship intake prevalence, adjusting for demographic health-related covariates such as age, sex, BMI, diabetes status, physical activity, other factors. Additional analyses conducted explore effects percentage total energy impact various ratios. Higher intakes SFA, MUFA, PUFA associated increased odds prevalence. Specifically, each 10 g/day increase was linked 22% [OR = 1.22, 95% CI: 1.11–1.34, p 0.002], 10% 1.10, 1.00–1.22, 0.052] 21% 1.21, 1.10–1.33, 0.001] higher stones, respectively. These associations generally consistent across subgroups. examining ratios yielded compatible findings. The findings suggest modest While observed increases relatively small, these results highlight importance considering types Future research is needed further elucidate underlying mechanisms refine recommendations.

Language: Английский

Citations

0
Association between life’s essential 8 and bone mineral density among adults aged 20–59 years DOI Creative Commons

Yuyu Cui,

Zhening Xu,

Zhaoshu Cui

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 21, 2025

This study investigates the relationship between Life's Essential 8 (LE8) scores and bone mineral density (BMD) in adults aged 20–59 years. cross-sectional analysis employed nationally representative data from NHANES 2011–2018. Weighted multiple linear regression models were applied to assess association LE8 varying levels of cardiovascular health (CVH) with BMD. Subgroup analyses performed evaluate differences impact on BMD across age groups, genders, races, socioeconomic statuses, BMI categories. The included 2159 participants. After adjusting for all covariates, demonstrated a significant positive lumbar spine BMD, thoracic trunk total Individuals medium high CVH groups exhibited higher compared those low group. indicated that was more evident participants 20–35 years among normal BMI. In females, appeared particularly sensitive changes scores. identifies Higher linked greater These findings highlight importance adopting comprehensive strategies, suggesting improving may contribute maintaining supporting skeletal health.

Language: Английский

Citations

0
Association of serum neurofilament light chain and bone mineral density in adults DOI Creative Commons

Meng‐Ning Lan,

Mingming Gao

BMC Musculoskeletal Disorders, Journal Year: 2025, Volume and Issue: 26(1)

Published: April 21, 2025

Language: Английский

Citations

0