Comparative evaluation of sticky bone with guided tissue regeneration and platelet-rich fibrin membranes in healing of apicomarginal defects with periapical pathology: An in-vivo study DOI Creative Commons

Dipkana Das,

Parthasarathi Mondal,

Kallol Kumar Saha

et al.

Endodontics Today, Journal Year: 2024, Volume and Issue: 22(4), P. 335 - 343

Published: Dec. 29, 2024

AIM. The objective of this study is to comparatively evaluate the effectiveness sticky bone alone, with a PRF membrane, as well having GTR membrane in healing apicomarginal defects. MATERIALS AND METHODS. Twenty-seven patients defects were randomly divided into three groups: Group I (sticky alone), II membrane), and III membrane). Clinical radiographic assessments, including probing depth, density, lesion size, conducted. Statistical analyses included paired t-tests ANOVA remarkable level p < 0.05. RESULTS. Notable improvements all parameters observed across groups (p 0.05). showed most notable reductions depth size highest increase density. exhibited moderate improvements, while had least favorable outcomes. CONCLUSION. Combining or enhances defects, yielding best results.

Language: Английский

Efficacy of different forms of concentrated growth factors combined with deproteinized bovine bone minerals in guided bone regeneration: a randomized clinical trial DOI Creative Commons
Lei Zhu, Xiaoqing Du, Gang Fu

et al.

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 28, 2025

Language: Английский

Citations

1
Autologous and Heterologous Minor and Major Bone Regeneration with Platelet-Derived Growth Factors DOI Creative Commons
Gianna Dipalma, Angelo Michele Inchingolo, Valeria Colonna

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(1), P. 16 - 16

Published: Jan. 9, 2025

This review aims to explore the clinical applications, biological mechanisms, and potential benefits of concentrated growth factors (CGFs), autologous materials, xenografts in bone regeneration, particularly dental treatments such as alveolar ridge preservation, mandibular osteonecrosis, peri-implantitis. A systematic literature search was conducted using databases like PubMed, Scopus, Web Science, with keywords "bone regeneration" "CGF" from 2014 2024. Only English-language studies involving human subjects were included. total 10 selected for qualitative analysis. Data processed through multiple stages, including title abstract screening full-text evaluation. The findings reviewed underscore CGF enhancing regeneration stimulating cell proliferation, angiogenesis, extracellular matrix mineralization. Autologous materials have also demonstrated promising results due their biocompatibility capacity seamless integration natural tissue. When combined xenografts, these show synergistic effects improving quantity quality, which are crucial implant success. Future research should focus on direct comparisons different techniques, optimization protocols, broader applications beyond medicine. CGFs into routine practice represents a significant advancement regenerative medicine, improved patient outcomes satisfaction.

Language: Английский

Citations

0
Immediate Implant Placement in the Esthetic Zone with Marginal Preservation: Esthetic Outcomes in Sites with Thin Buccal Bone Wall DOI
Thanh Huy Thai, Phuong Nguyen, Hao Trong Nguyen

et al.

Journal of Maxillofacial and Oral Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 4, 2025

Language: Английский

Citations

0
Growth Factors Release in Concentrated Growth Factor and Advanced Platelet‐Rich Fibrin Sticky Bone DOI
Siniong Iao, W Liu, Jing Qiao

et al.

Oral Diseases, Journal Year: 2025, Volume and Issue: unknown

Published: May 6, 2025

ABSTRACT Objective Sticky bone, created from concentrated growth factor (CGF) or advanced platelet‐rich fibrin (A‐PRF), contains various factors. This study analyzed the release patterns of factors CGF sticky bone (CGF‐SB) and A‐PRF (A‐PRF‐SB) to inform their application in grafting. Methods CGF, A‐PRF, CGF‐SB, A‐PRF‐SB were incubated for 28 days, with supernatant collected on days 1, 7, 14, 21, 28. Growth factors—platelet‐derived factor‐BB (PDGF‐BB), vascular endothelial (VEGF), basic fibroblast (bFGF)—were quantified using multiplex assays. Transforming factor‐β1 (TGF‐β1) insulin‐like factor‐1 (IGF‐1) measured by ELISA. Results released more than half PDGF‐BB, VEGF, bFGF within day followed rapid declines. Differently, these gradually, surpassing 50% cumulative 7 sustaining over time. IGF‐1 TGF‐β1 all groups reached respectively. significantly bFGF, CGF‐SB ( p < 0.05). Conclusions Both exhibit slower sustained compared alone, offering superior profiles, highlighting its enhanced potential grafting applications.

Language: Английский

Citations

0
Role of Sticky Bone in the Management of Various Alveolar Bone Defects: A Systematic Review DOI Open Access

Vidhuta Sareen,

K Santhi,

Isha Saxena

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: July 1, 2024

Aim: This systematic review aimed to evaluate the effectiveness of sticky bone in managing various alveolar defects, examining both its benefits and drawbacks. Materials methods: The adhered PRISMA guidelines employed a thorough search strategy using major databases, medical subject headings (MeSH) keywords, Boolean operators. As result, identified 12 studies focusing on efficacy treating defects. Inclusion criteria consisted randomized controlled trials case series reporting outcomes use for defect treatment. Two examiners meticulously performed screening, data extraction, bias assessment, with risk evaluated Cochrane tool. Result: findings indicated significant improvements quality, width, height, volume, enhanced predictability socket preservation implant placement. Sticky was particularly effective ridge augmentation, guided regeneration, filling periodontal often outperforming alternatives like concentrated growth factors (CGFs) autologous fibrin glue (AFG). It simplified procedures reduced resorption during healing, underscoring value as versatile adjunct reconstruction surgery. Conclusion: demonstrated exceptional results oral surgeries, effectively addressing issues such furcation loss, clinical radiographic improvements. Further research is needed explore full potential refine protocols broader surgery periodontics applications.

Language: Английский

Citations

1
Subperiosteal Ridge Augmentation Technique Utilizing Sticky Bone: A Case Series DOI Open Access

Kandhal Yazhini P,

Nidhita Suresh, Gurumoorthy Kaarthikeyan

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

This case series presents the application of a novel minimally invasive technique for augmenting ridge defects across four edentulous sites, thereby circumventing common postoperative complications associated with conventional augmentation techniques. The details three cases encompassing sites class I and III defects. approach uses subperiosteal augmentation, followed by delayed implant placement. Subperiosteal incisions were made mesial to pouches created using tunneling instruments. Sticky bone (comprising injectable platelet-rich fibrin (IPRF) xenograft) was applied pouches, Vicryl suturing. cone-beam computed tomography (CBCT) assessed dimensional changes between baseline 180 days post-ridge augmentation. Subsequently, during insertion after days, samples collected, decalcified 10% formic acid, sectioned thickness 5 µm. Histological analysis conducted bright field microscope, while histomorphometric carried out Image J software. modified employed in this report, coupled sticky as an material, demonstrates promise reliable method

Language: Английский

Citations

1
Osseodensification versus piezoelectric internal sinus elevation (PISE) technique in delayed implant placement (a randomized controlled clinical trial) DOI Creative Commons
Mohammed Samir,

Mohamed Wagdy Bissar,

Hala Ahmed Abuel-Ela

et al.

BMC Oral Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 28, 2024

Abstract Transalveolar sinus elevation is a minimally invasive technique aimed at augmenting the vertical bone height in posterior maxilla, facilitating successful implant placement areas with insufficient volume. This study compares efficacy of osseodensification and piezoelectric internal (PISE) techniques delayed placement. The primary objective was to radiographically assess gain density, while secondary objectives included clinical assessment stability post-operative satisfaction both patients operators. population total 16 randomly divided into two groups. Group 1 underwent lift using sticky as graft material, whereas 2 received PISE same material. Results indicated that led greater gain, improved shorter surgical duration. Additionally, associated enhanced rapid healing higher patient satisfaction. Conversely, demonstrated superior implants on day surgery. These findings suggest are effective, may offer advantages terms satisfaction, making it reliable method for enhancing registered clinicaltrials.gov 26 th September 2023 trials ID NCT06055127 .

Language: Английский

Citations

0
Comparative evaluation of sticky bone with guided tissue regeneration and platelet-rich fibrin membranes in healing of apicomarginal defects with periapical pathology: An in-vivo study DOI Creative Commons

Dipkana Das,

Parthasarathi Mondal,

Kallol Kumar Saha

et al.

Endodontics Today, Journal Year: 2024, Volume and Issue: 22(4), P. 335 - 343

Published: Dec. 29, 2024

AIM. The objective of this study is to comparatively evaluate the effectiveness sticky bone alone, with a PRF membrane, as well having GTR membrane in healing apicomarginal defects. MATERIALS AND METHODS. Twenty-seven patients defects were randomly divided into three groups: Group I (sticky alone), II membrane), and III membrane). Clinical radiographic assessments, including probing depth, density, lesion size, conducted. Statistical analyses included paired t-tests ANOVA remarkable level p < 0.05. RESULTS. Notable improvements all parameters observed across groups (p 0.05). showed most notable reductions depth size highest increase density. exhibited moderate improvements, while had least favorable outcomes. CONCLUSION. Combining or enhances defects, yielding best results.

Language: Английский

Citations

0