Pharmacological and non-pharmacological approaches to temporomandibular disorder chronic pain: a narrative review
Fanny Jogna,
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Adriana Graenicher A,
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Quentin Rey-Millet
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et al.
Pain Management,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 12
Published: May 8, 2025
Temporomandibular
disorders
(TMD)
involve
the
temporomandibular
joint
and
related
structures,
causing
chronic
pain,
impaired
jaw
function,
reduced
quality
of
life.
TMD
has
multifactorial
origins,
including
mechanical,
neuromuscular,
inflammatory
factors.
Chronic
pain
is
difficult
to
manage
due
its
complex
pathophysiology
limited
long-term
effectiveness
existing
treatments.
A
combination
pharmacological
non-pharmacological
strategies
essential
for
optimal
management.
This
narrative
review
provides
an
integrative
overview
current
treatments
TMD-associated
pain.
Pharmacological
options
discussed
include
analgesics,
muscle
relaxants,
antidepressants,
anticonvulsants,
botulinum
toxin
injections.
Non-pharmacological
physical
therapy,
cognitive-behavioral
acupuncture,
lifestyle
modifications.
comprehensive
literature
search
was
conducted
using
PubMed,
Embase.com,
Cochrane,
Evidence
Alerts
databases
through
October
2024.
We
focused
on
original
research
articles,
randomized
controlled
trials,
systematic
reviews,
meta-analyses.
Effective
management
requires
a
multidisciplinary
approach
tailored
individual
needs.
supports
integration
psychological
therapies
into
treatment
plans.
Future
should
aim
develop
targeted
interventions
that
address
underlying
mechanisms
evaluate
outcomes
noninvasive
therapies.
Language: Английский
Arthrocentesis of Temporomandibular Joints—A Clinical Comparative Study
Life,
Journal Year:
2024,
Volume and Issue:
14(12), P. 1594 - 1594
Published: Dec. 3, 2024
The
objective
of
this
study
was
to
compare
single-needle
arthrocentesis
with
the
conventional
two-needle
arthrocentesis,
as
well
additional
intracapsular
injection
hyaluronic
acid
or
platelet-rich
fibrin.
A
total
96
patients
established
osteoarthritis
(OA)
(n
=
48)
internal
de-arrangement
(DD)
were
assigned
distension
joint
without
medication
(hyaluronic
(HA)
plasma
(PRP))
performed
every
month
over
a
period
6
months.
maximum
mouth
opening
and
pain,
measured
by
visual
analog
scale
(VAS),
compared.
Each
group
exhibited
significant
improvement,
i.e.,
decrease
in
pain
an
increase
opening.
single-puncture
technique
provided
similar
reduction
approach
but
significantly
better
results
terms
when
comparing
OA
DD
cohorts;
however,
disc
displacement
achieved
than
OA.
Intracapsular
application
contributed
both
HA
PRP
groups,
fibrin
being
superior
improvement.
Language: Английский