Role of Cyclins and Cytoskeletal Proteins in Endometriosis: Insights into Pathophysiology DOI Open Access
Marcin Szymański, Klaudia Bonowicz, Paulina Antosik

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(4), P. 836 - 836

Published: Feb. 19, 2024

Endometriosis is a gynecological condition where endometrium-like tissue grows outside the uterus, posing challenges in understanding and treatment. This article delves into deep cellular molecular processes underlying endometriosis, with focus on crucial roles played by cyclins cytoskeletal proteins its pathogenesis, particularly context of Epithelial–Mesenchymal Transition (EMT). The investigation begins examining activities cyclins, elucidating their diverse biological such as cell cycle control, proliferation, evasion apoptosis, angiogenesis among ectopic endometrial cells. A comprehensive analysis follows, emphasizing fundamental specific significance to endometriotic features. review sheds light interconnected pathways through which converge, contributing genesis progression endometriosis. Understanding these complexities not only provides insight causes disease but also holds promise for development therapeutic approaches, ushering new era management this devastating disorder.

Language: Английский

Role of Cyclins and Cytoskeletal Proteins in Endometriosis: Insights into Pathophysiology DOI Open Access
Marcin Szymański, Klaudia Bonowicz, Paulina Antosik

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(4), P. 836 - 836

Published: Feb. 19, 2024

Endometriosis is a gynecological condition where endometrium-like tissue grows outside the uterus, posing challenges in understanding and treatment. This article delves into deep cellular molecular processes underlying endometriosis, with focus on crucial roles played by cyclins cytoskeletal proteins its pathogenesis, particularly context of Epithelial–Mesenchymal Transition (EMT). The investigation begins examining activities cyclins, elucidating their diverse biological such as cell cycle control, proliferation, evasion apoptosis, angiogenesis among ectopic endometrial cells. A comprehensive analysis follows, emphasizing fundamental specific significance to endometriotic features. review sheds light interconnected pathways through which converge, contributing genesis progression endometriosis. Understanding these complexities not only provides insight causes disease but also holds promise for development therapeutic approaches, ushering new era management this devastating disorder.

Language: Английский

Citations

6