Suicide by Firearm and Hormonal Imbalances: A Forensic Case Report With Literature Review

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Hormonal imbalances play a crucial role in the development of various diseases, with significant impact on gynecological system, especially onset uterine fibroids (UFs). UFs, also known as myomas or leiomyomas, are noncancerous growths commonly observed women, particularly during their reproductive years. By age 50, many women experience fibroids, though condition's prevalence varies significantly across different ethnic groups. While most remain asymptomatic, those that symptomatic can lead to several issues, such irregular bleeding, pelvic discomfort, and complications pregnancy. Receiving diagnosis be distressing, when concerns arise about potential link more serious conditions. This distress adversely affect woman's quality life mental health, sometimes contributing emotional distress, depressive symptoms, even suicidal ideation. The management UFs encompasses spectrum approaches, from careful monitoring medical surgical interventions, which chosen based severity symptoms patient's preferences. Psychological support valuable helping manage anxiety fears associated treatment process. Consequently, women's health warrants attention. paper aims review existing scientific literature between hormonal imbalances, an increased risk psychiatric disorders.

Language: Английский

Causality between neuroticism personality clusters and female reproductive diseases in European population: a two-sample bidirectional mendelian randomization study

BMC Women s Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 12, 2024

The causality between neuroticism, a personality trait characterized by the tendency to experience negative emotions, and female reproductive diseases remains unclear. To provide evidence for development of effective screening prevention strategies, this study employed Mendelian randomization (MR) investigate neuroticism clusters diseases.

Language: Английский

The genetic associations between gut microbiota and menstruation quality of life impacts in the East Asian women

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 23, 2024

Background Menstruation affects the physiological and psychological health of East Asian women, imposing burdens on their daily lives work. The gut microbiota has been found to improve various diseases. study used Mendelian randomization exploratorily discuss causal effects menstruation quality life impacts. Methods According predefined threshold, independent genetic variants significantly linked 119 bacterial genera in were extracted as instrumental variables. inverse variance weighted (IVW) was utilized primary analysis method, supplemented by MR-Egger Weighted median methods. Effect estimates assessed primarily using odds ratios (OR) 95% confidence intervals (95%CI). In addition, sensitivity analyses (heterogeneity, horizontal pleiotropy, outliers) implemented evaluate robustness accuracy findings. Results Causal between 28 13 Based OR, 18 identified risk factors, while 10 protective factors. Furthermore, did not detect heterogeneity, or outliers. Conclusions This provides evidence for These findings will help elucidate how could affect issues during menstruation. they also offer valuable perspectives into management women's

Language: Английский