IOP Conference Series Earth and Environmental Science, Journal Year: 2024, Volume and Issue: 1428(1), P. 012012 - 012012
Published: Dec. 1, 2024
Abstract Oxidative stress is linked to various diseases, including cancer and cardiovascular disorders, due the imbalance between reactive oxygen species body’s antioxidant defenses. The use of natural antioxidants presents a sustainable approach mitigating oxidative damage, aligning with Sustainable Development Goals 3 12. This study evaluates impact repeated oral administration Terminalia catappa aqueous extract (AETC) on activities in Wistar rats over 28 days. enzymatic non-enzymatic concentration endogenous were investigated plasma tissues at end experiment. Results indicated increased renal superoxide dismutase, hepatic peroxidase, erythrocyte glutathione-S-transferase activities. Hepatic reduced glutathione was while malondialdehyde concentrations reduced. These results emphasise AETC’s tissue-specific effects its potential as protective agent against consolidating ethnobotanical leaves tonic for health-improving benefits promoting good health addition advocating ecofriendly solutions. Further elucidatation AETC mechanisms optimisation therapeutic applications required.
Language: Английский