Real‐time genomics for One Health

Molecular Systems Biology, Journal Year: 2023, Volume and Issue: 19(8)

Published: June 16, 2023

The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to future relationship planet. While the concept One Health describes how human health is inextricably linked health, many these complex interdependencies are still not well-understood. Here, we describe advent real-time genomic analyses can benefit it enable timely, in-depth ecosystem assessments. We introduce nanopore sequencing as only disruptive technology that currently allows for already being used worldwide improve accessibility versatility sequencing. showcase studies on zoonotic disease, food security, microbiome, emerging pathogens, their antimicrobial resistances, itself - from resource creation wildlife conservation monitoring biodiversity, invasive species, trafficking. stress why equitable access genomics in context will be paramount discuss related practical, legal, ethical limitations.

Language: Английский

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A comparative genomic analysis at the chromosomal-level reveals evolutionary patterns of aphid chromosomes

Communications Biology, Journal Year: 2025, Volume and Issue: 8(1)

Published: March 13, 2025

Genomic rearrangements are primary drivers of evolution, promoting biodiversity. Aphids, an agricultural pest with high species diversity, exhibit rapid chromosomal evolution and diverse karyotypes. These variations have been attributed to their unique holocentric chromosomes parthenogenesis, though this hypothesis has faced scrutiny. In study, we generated a chromosomal-level reference genome assembly the celery aphid (Semiaphis heraclei) conducted comparative genomic analysis, revealing varying rates among lineages, positively correlating diversity. Aphid X undergone frequent intra-chromosomal recombination, while autosomes show accelerated inter-chromosomal recombination. Moreover, considering both inter- rearrangements, increased autosomal rearrangement may be common across Aphidomorpha. We identified that expansion DNA transposable elements short interspersed nuclear (SINEs), coupled gene loss duplication associated karyotypic instability (such as RIF1, BRD8, DMC1, TERT), play crucial roles in evolution. Additionally, our analysis revealed mutation detoxification families S. heraclei key factor adapting host plant chemical defenses. Our results provide new insights into evolutionary patterns aphids, aiding understanding diversity adaptive Chromosomal-level comparisons

Language: Английский

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Functional analyses of the salivary protein SaE23 in Sitobion avenae

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142068 - 142068

Published: March 1, 2025

Language: Английский

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Hybridisation has shaped a recent radiation of grass-feeding aphids

BMC Biology, Journal Year: 2023, Volume and Issue: 21(1)

Published: July 13, 2023

Aphids are common crop pests. These insects reproduce by facultative parthenogenesis involving several rounds of clonal reproduction interspersed with an occasional sexual cycle. Furthermore, aphids give birth to live young that already pregnant. qualities enable rapid population growth and have facilitated the colonisation crops globally. In cases, so-called "super clones" come dominate agricultural systems. However, extent which stage aphid life cycle has shaped global pest populations remained unclear, as origins successful lineages. Here, we used chromosome-scale genome assemblies disentangle evolution two pests cereals-the English (Sitobion avenae) Indian miscanthi) grain aphids.

Language: Английский

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Female alternative reproductive tactics: diversity and drivers

Trends in Ecology & Evolution, Journal Year: 2024, Volume and Issue: 39(10), P. 937 - 946

Published: July 1, 2024

It is often argued that anisogamy causes alternative reproductive tactics (ARTs) to be more common in males than females. We challenge this view by pointing out logical flaws the argument. then review recent work on diversity of female ARTs, listing several understudied types such as solitary versus communal breeding and facultative parthenogenesis. highlight an important difference between male ARTs caused overlooked: tend focus successful fertilization, whereas occur at many stages reproduction form complex networks decision points. propose study correlated a whole better understand their drivers eco-evolutionary dynamics.

Language: Английский

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A comparative genomic analysis at the chromosomal-level reveals evolutionary patterns of aphid chromosomes

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 13, 2024

Genomic rearrangements are primary drivers of evolution, promoting biodiversity and differentiation. Aphids, an agricultural pest with high species diversity, exhibit rapid chromosomal evolution a wide range nuclear karyotype variations. These variations have been attributed to their unique holocentric chromosomes parthenogenetic generations, though this hypothesis has also faced scrutiny. An in-depth comparative genomics analysis aphid genomic will enhance our understanding diversity evolution. In study, by generating chromosomal-level reference genome assembly the celery (Semiaphis heraclei) conducting analysis, we revealed varying rates among lineages, positively correlating diversity. Aphid X undergone frequent intra-chromosomal recombination, while autosomes show accelerated inter-chromosomal recombination. Moreover, considering both inter- rearrangements, increased autosomal rearrangement may be common across Aphidomorpha lineage. Additionally, expansion DNA SINE-type transposable elements, along gene loss duplication associated karyotypic instability (such as, RIF1, BRD8, DMC1, TERT), play crucial roles in Our results provide new insights into evolutionary patterns, which helpful for genetic mechanisms behind adaptive

Language: Английский

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Exploring innovative strategies to control aphids: meta-analysis and a critical view on what we have and what the future is

Journal of Pest Science, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

Language: Английский

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