Nutrition Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 15, 2025
Abstract
Context
Although
low-carbohydrate
(LC)
diets
have
been
shown
to
be
beneficial
for
weight
loss
and
improvements
in
cardiometabolic
health
adults
with
obesity,
their
efficacy
youth
has
not
yet
established.
Objectives
A
systematic
review
meta-analysis
was
conducted
qualitatively
quantitively
synthesize
the
evidence
from
clinical
trials
testing
of
LC
improve
anthropometric
cardiometabolic-related
parameters
children
adolescents
obesity.
Data
Sources
Searches
Medline,
EMBASE,
Cochrane
databases
were
undertaken
interventions
or
without
control
comparisons.
Extraction
Analysis
before
after
intervention
comparisons
(if
applicable)
extracted
19
studies,
17
which
pooled
random-effects
meta-analyses.
Results
Children
on
(Mean
=
30
[IQR:
30-60]
g/d),
approximately
3
months
(IQR:
3-4
months)
significantly
reduced
(mean
change
[MC]
-7.09
[95%
CI:
-9.60,
-4.58]
kg;
P
<
.001),
body
mass
index
(BMI)
(MC
-3.01
[-3.71,
-2.30]
kg/m2;
BMI
z-score
-0.27
[-0.48,
-0.06];
.020),
average,
concomitant
different
metabolic
biomarkers,
such
as
serum
triglycerides
-29.16
[-45.06,
-13.26]
mg/dL;
.002)
insulin
-7.13
[-9.27,
-4.99]
µU/mL;
.001).
Evidence
5
out
7
controlled
suggests
that
caloric
restriction
may
lead
similar
greater
lipid-related
outcomes
relative
caloric-restricted
low-fat
diets.
However,
meta-analyses
demonstrated
high
between-study
heterogeneity,
indicative
a
wide
variety
methodologies,
including
duration
degree
carbohydrate
restriction.
Conclusion
Overall,
this
found
short-term
can
improving
calorie
limited
number
demonstrable
diversity
methods
prevent
firm
conclusions
regarding
traditional
approaches,
energy
Systematic
Review
Registration
PROSPERO
registration
no.
CRD42023440835.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(5), P. 818 - 818
Published: Feb. 27, 2025
Background/Objectives:
The
increasing
use
of
social
media
for
sharing
health
and
diet
experiences
presents
new
opportunities
nutritional
research
dietary
assessment.
Large
language
models
(LLMs)
artificial
intelligence
(AI)
offer
innovative
approaches
to
analyzing
self-reported
data
from
online
communities.
This
study
explores
weight
loss
associated
with
the
ketogenic
(KD)
using
user-generated
content
Reddit,
aiming
identify
trends
potential
biases
in
outcomes.
Methods:
A
dataset
35,079
Reddit
posts
related
KD
was
collected
processed.
Posts
mentioning
loss,
duration,
additional
factors
(age,
gender,
physical
activity,
conditions)
were
identified,
yielding
2416
complete
cases.
Descriptive
statistics
summarized
distributions
adherence
patterns,
while
linear
regression
examined
loss.
Results:
median
reported
10.9
kg
(IQR:
4.4-22.7
kg).
Diet
varied
36.3%
users
following
up
30
days
7.8%
more
than
a
year.
Metabolic
(27%)
cardiovascular
disorders
(17%)
most
frequently
conditions.
Adherence
beyond
one
year
an
average
28.2
(95%
CI:
25.5-30.9)
compared
days.
Male
gender
5.2
3.8-6.6)
females.
Conclusions:
Findings
suggest
may
lead
substantial
based
on
data.
highlights
value
research,
uncovering
hidden
patterns
that
could
inform
public
strategies
personalized
nutrition
plans.
Current Nutrition Reports,
Journal Year:
2025,
Volume and Issue:
14(1)
Published: March 8, 2025
Abstract
Purpose
of
Review
The
ketogenic
diet
(KD)
has
gained
clinical
attention
for
its
potential
benefits
in
weight
loss
and
metabolic
syndrome.
By
mimicking
fasting
through
carbohydrate
(CHO)
restriction,
KD
shifts
energy
utilization
to
ketone
bodies
(KB)
instead
glucose.
Despite
promising
results,
the
effects
on
different
indicators
remain
controversial,
with
challenges
monitoring
adherence
standards,
optimal
macronutrient
composition,
risks,
long-term
sustainability.
This
article
aims
review
weight-loss
outcomes
interventions
obesity,
monitored
by
KB
(adherence
indication).
Recent
Findings
Current
literature
obesity
show
reduction
outcomes,
including
body
weight,
mass
index,
waist
circumference,
visceral
adipose
tissue,
fat
mass,
percentage.
Minor
decreases
lean
skeletal
muscle
were
noted
without
resistance
training.
Variability
existed
(KB
markers),
CHO
intake
(7–27%
daily
energy),
duration
(28
days
12
months),
follow-up
frequency
(weekly
biannual).
KD,
particularly
accompanied
exercise,
positively
influenced
appetite
regulation.
Summary
improves
weight-related
participants
but
presents
training
variability.
Standardizing
methodologies,
refining
suitability
sub-populations,
setting
markers,
defining
relevance
are
essential
optimizing
effectiveness.
Graphical
physiological
effect
Ketogenic
diets
are
emerging
dietary
patterns
that
have
demonstrated
potential
as
therapeutic
tools
in
a
variety
of
symptoms
and
conditions,
such
epileptic
seizures,
diabetes,
obesity,
cancer,
migraines,
metabolic
syndrome.
This
narrative
review
examines
the
effects
ketogenic
on
physiological
mental
health,
including
their
role
modulating
gut
microbiome.
promote
weight
loss,
enhance
insulin
sensitivity,
may
lower
dyslipidemia,
which
crucial
factors
preventing
cardio-metabolic
diseases.
They
also
play
significant
composition
function
microbiome,
serving
approach
to
control
autoimmune
diseases,
given
effectiveness
reducing
pro-inflammatory
cells.
Conversely,
downside
these
is
decrease
beneficial
bacteria
been
positively
associated
with
human
health.
Regarding
capability
stabilize
neural
networks,
improve
neuroplasticity,
exert
direct
benefits
brain
bioenergetics,
thereby
potentially
alleviating
related
several
epilepsy,
anxiety,
depression,
schizophrenia,
bipolar
disorder,
autism
spectrum
certain
neurodegenerative
However,
more
randomized,
long-term
studies
required
assess
efficacy,
sustainability,
safety,
methodological
rigor
strengthen
findings
impacts.
BMC Cardiovascular Disorders,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: March 26, 2025
Abstract
Background
Numerous
studies
have
shown
that
exercise
and
dietary
interventions
positively
impact
CVD
outcomes;
however,
there
is
substantial
variability
in
the
efficacy
of
different
interventions.
The
absence
direct
comparisons
between
multiple
complicates
determination
their
relative
effects.
This
study
aims
to
synthesize
literature
on
impacts
exercise,
dietary,
combined
cardiovascular
health
indicators,
perform
a
network
meta-analysis
rank
these
approaches,
providing
theoretical
foundation
for
selecting
optimal
intervention
strategies.
Methods
We
systematically
reviewed
from
database
inception
through
September
2024,
searching
PubMed,
Web
Science,
Embase,
Cochrane
Library.
Data
were
aggregated
analyzed
using
meta-analysis,
with
ranked
according
Surface
Under
Cumulative
Ranking
(SUCRA)
curves.
Results
was
as
follows:
1).
Triglycerides
(TG)
Reduction:
CR
+
EX
>
5/2F
TRF
KD
CON
TRF.
2).
Total
Cholesterol
(TC)
EX.
3).
High-Density
Lipoprotein
(HDL)
Increase:
CR.
4).
Low-Density
(LDL)
5).
Systolic
Blood
Pressure
(SBP)
6).
Diastolic
(DBP)
Conclusion
demonstrated
most
positive
effects
indicators.
In
contrast,
relatively
low
effectiveness,
its
several
indicators
being
even
lower
than
CON.
Nutrition Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 15, 2025
Abstract
Context
Although
low-carbohydrate
(LC)
diets
have
been
shown
to
be
beneficial
for
weight
loss
and
improvements
in
cardiometabolic
health
adults
with
obesity,
their
efficacy
youth
has
not
yet
established.
Objectives
A
systematic
review
meta-analysis
was
conducted
qualitatively
quantitively
synthesize
the
evidence
from
clinical
trials
testing
of
LC
improve
anthropometric
cardiometabolic-related
parameters
children
adolescents
obesity.
Data
Sources
Searches
Medline,
EMBASE,
Cochrane
databases
were
undertaken
interventions
or
without
control
comparisons.
Extraction
Analysis
before
after
intervention
comparisons
(if
applicable)
extracted
19
studies,
17
which
pooled
random-effects
meta-analyses.
Results
Children
on
(Mean
=
30
[IQR:
30-60]
g/d),
approximately
3
months
(IQR:
3-4
months)
significantly
reduced
(mean
change
[MC]
-7.09
[95%
CI:
-9.60,
-4.58]
kg;
P
<
.001),
body
mass
index
(BMI)
(MC
-3.01
[-3.71,
-2.30]
kg/m2;
BMI
z-score
-0.27
[-0.48,
-0.06];
.020),
average,
concomitant
different
metabolic
biomarkers,
such
as
serum
triglycerides
-29.16
[-45.06,
-13.26]
mg/dL;
.002)
insulin
-7.13
[-9.27,
-4.99]
µU/mL;
.001).
Evidence
5
out
7
controlled
suggests
that
caloric
restriction
may
lead
similar
greater
lipid-related
outcomes
relative
caloric-restricted
low-fat
diets.
However,
meta-analyses
demonstrated
high
between-study
heterogeneity,
indicative
a
wide
variety
methodologies,
including
duration
degree
carbohydrate
restriction.
Conclusion
Overall,
this
found
short-term
can
improving
calorie
limited
number
demonstrable
diversity
methods
prevent
firm
conclusions
regarding
traditional
approaches,
energy
Systematic
Review
Registration
PROSPERO
registration
no.
CRD42023440835.