Low-Carbohydrate Diets for the Management of Pediatric Obesity: A Systematic Review and Meta-analysis DOI
E Fournier, Halim Moore, Zainab S. Alghamdi

et al.

Nutrition Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Abstract Context Although low-carbohydrate (LC) diets have been shown to be beneficial for weight loss and improvements in cardiometabolic health adults with obesity, their efficacy youth has not yet established. Objectives A systematic review meta-analysis was conducted qualitatively quantitively synthesize the evidence from clinical trials testing of LC improve anthropometric cardiometabolic-related parameters children adolescents obesity. Data Sources Searches Medline, EMBASE, Cochrane databases were undertaken interventions or without control comparisons. Extraction Analysis before after intervention comparisons (if applicable) extracted 19 studies, 17 which pooled random-effects meta-analyses. Results Children on (Mean = 30 [IQR: 30-60] g/d), approximately 3 months (IQR: 3-4 months) significantly reduced (mean change [MC] -7.09 [95% CI: -9.60, -4.58] kg; P < .001), body mass index (BMI) (MC -3.01 [-3.71, -2.30] kg/m2; BMI z-score -0.27 [-0.48, -0.06]; .020), average, concomitant different metabolic biomarkers, such as serum triglycerides -29.16 [-45.06, -13.26] mg/dL; .002) insulin -7.13 [-9.27, -4.99] µU/mL; .001). Evidence 5 out 7 controlled suggests that caloric restriction may lead similar greater lipid-related outcomes relative caloric-restricted low-fat diets. However, meta-analyses demonstrated high between-study heterogeneity, indicative a wide variety methodologies, including duration degree carbohydrate restriction. Conclusion Overall, this found short-term can improving calorie limited number demonstrable diversity methods prevent firm conclusions regarding traditional approaches, energy Systematic Review Registration PROSPERO registration no. CRD42023440835.

Language: Английский

AI-Powered Analysis of Weight Loss Reports from Reddit: Unlocking Social Media’s Potential in Dietary Assessment DOI Open Access
Efstathios Kaloudis,

Victoria Kouti,

Foteini-Maria Triantafillou

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 818 - 818

Published: Feb. 27, 2025

Background/Objectives: The increasing use of social media for sharing health and diet experiences presents new opportunities nutritional research dietary assessment. Large language models (LLMs) artificial intelligence (AI) offer innovative approaches to analyzing self-reported data from online communities. This study explores weight loss associated with the ketogenic (KD) using user-generated content Reddit, aiming identify trends potential biases in outcomes. Methods: A dataset 35,079 Reddit posts related KD was collected processed. Posts mentioning loss, duration, additional factors (age, gender, physical activity, conditions) were identified, yielding 2416 complete cases. Descriptive statistics summarized distributions adherence patterns, while linear regression examined loss. Results: median reported 10.9 kg (IQR: 4.4-22.7 kg). Diet varied 36.3% users following up 30 days 7.8% more than a year. Metabolic (27%) cardiovascular disorders (17%) most frequently conditions. Adherence beyond one year an average 28.2 (95% CI: 25.5-30.9) compared days. Male gender 5.2 3.8-6.6) females. Conclusions: Findings suggest may lead substantial based on data. highlights value research, uncovering hidden patterns that could inform public strategies personalized nutrition plans.

Language: Английский

Citations

0

Ketogenic Diet Intervention for Obesity Weight-Loss- A Narrative Review, Challenges, and Open Questions DOI Creative Commons

Adina Bachar,

Ruth Birk

Current Nutrition Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 8, 2025

Abstract Purpose of Review The ketogenic diet (KD) has gained clinical attention for its potential benefits in weight loss and metabolic syndrome. By mimicking fasting through carbohydrate (CHO) restriction, KD shifts energy utilization to ketone bodies (KB) instead glucose. Despite promising results, the effects on different indicators remain controversial, with challenges monitoring adherence standards, optimal macronutrient composition, risks, long-term sustainability. This article aims review weight-loss outcomes interventions obesity, monitored by KB (adherence indication). Recent Findings Current literature obesity show reduction outcomes, including body weight, mass index, waist circumference, visceral adipose tissue, fat mass, percentage. Minor decreases lean skeletal muscle were noted without resistance training. Variability existed (KB markers), CHO intake (7–27% daily energy), duration (28 days 12 months), follow-up frequency (weekly biannual). KD, particularly accompanied exercise, positively influenced appetite regulation. Summary improves weight-related participants but presents training variability. Standardizing methodologies, refining suitability sub-populations, setting markers, defining relevance are essential optimizing effectiveness. Graphical physiological effect

Language: Английский

Citations

0

Therapeutic effects of ketogenic diets on physiological and mental health DOI Creative Commons
Alejandro Borrego-Ruiz, Juan J. Borrego

Published: March 25, 2025

Ketogenic diets are emerging dietary patterns that have demonstrated potential as therapeutic tools in a variety of symptoms and conditions, such epileptic seizures, diabetes, obesity, cancer, migraines, metabolic syndrome. This narrative review examines the effects ketogenic on physiological mental health, including their role modulating gut microbiome. promote weight loss, enhance insulin sensitivity, may lower dyslipidemia, which crucial factors preventing cardio-metabolic diseases. They also play significant composition function microbiome, serving approach to control autoimmune diseases, given effectiveness reducing pro-inflammatory cells. Conversely, downside these is decrease beneficial bacteria been positively associated with human health. Regarding capability stabilize neural networks, improve neuroplasticity, exert direct benefits brain bioenergetics, thereby potentially alleviating related several epilepsy, anxiety, depression, schizophrenia, bipolar disorder, autism spectrum certain neurodegenerative However, more randomized, long-term studies required assess efficacy, sustainability, safety, methodological rigor strengthen findings impacts.

Language: Английский

Citations

0

Effects of exercise combined with different dietary interventions on cardiovascular health a systematic review and network meta-analysis DOI Creative Commons

Y.J. Hei,

Yongchao Xie

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 26, 2025

Abstract Background Numerous studies have shown that exercise and dietary interventions positively impact CVD outcomes; however, there is substantial variability in the efficacy of different interventions. The absence direct comparisons between multiple complicates determination their relative effects. This study aims to synthesize literature on impacts exercise, dietary, combined cardiovascular health indicators, perform a network meta-analysis rank these approaches, providing theoretical foundation for selecting optimal intervention strategies. Methods We systematically reviewed from database inception through September 2024, searching PubMed, Web Science, Embase, Cochrane Library. Data were aggregated analyzed using meta-analysis, with ranked according Surface Under Cumulative Ranking (SUCRA) curves. Results was as follows: 1). Triglycerides (TG) Reduction: CR + EX > 5/2F TRF KD CON TRF. 2). Total Cholesterol (TC) EX. 3). High-Density Lipoprotein (HDL) Increase: CR. 4). Low-Density (LDL) 5). Systolic Blood Pressure (SBP) 6). Diastolic (DBP) Conclusion demonstrated most positive effects indicators. In contrast, relatively low effectiveness, its several indicators being even lower than CON.

Language: Английский

Citations

0

Low-Carbohydrate Diets for the Management of Pediatric Obesity: A Systematic Review and Meta-analysis DOI
E Fournier, Halim Moore, Zainab S. Alghamdi

et al.

Nutrition Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Abstract Context Although low-carbohydrate (LC) diets have been shown to be beneficial for weight loss and improvements in cardiometabolic health adults with obesity, their efficacy youth has not yet established. Objectives A systematic review meta-analysis was conducted qualitatively quantitively synthesize the evidence from clinical trials testing of LC improve anthropometric cardiometabolic-related parameters children adolescents obesity. Data Sources Searches Medline, EMBASE, Cochrane databases were undertaken interventions or without control comparisons. Extraction Analysis before after intervention comparisons (if applicable) extracted 19 studies, 17 which pooled random-effects meta-analyses. Results Children on (Mean = 30 [IQR: 30-60] g/d), approximately 3 months (IQR: 3-4 months) significantly reduced (mean change [MC] -7.09 [95% CI: -9.60, -4.58] kg; P < .001), body mass index (BMI) (MC -3.01 [-3.71, -2.30] kg/m2; BMI z-score -0.27 [-0.48, -0.06]; .020), average, concomitant different metabolic biomarkers, such as serum triglycerides -29.16 [-45.06, -13.26] mg/dL; .002) insulin -7.13 [-9.27, -4.99] µU/mL; .001). Evidence 5 out 7 controlled suggests that caloric restriction may lead similar greater lipid-related outcomes relative caloric-restricted low-fat diets. However, meta-analyses demonstrated high between-study heterogeneity, indicative a wide variety methodologies, including duration degree carbohydrate restriction. Conclusion Overall, this found short-term can improving calorie limited number demonstrable diversity methods prevent firm conclusions regarding traditional approaches, energy Systematic Review Registration PROSPERO registration no. CRD42023440835.

Language: Английский

Citations

0