Adverse Childhood Experiences and Nonsuicidal Self-Injury and Suicidality in Chinese Adolescents DOI Creative Commons

Yitong He,

Weiqing Jiang, Wanxin Wang

et al.

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(12), P. e2452816 - e2452816

Published: Dec. 30, 2024

Importance Studies investigating the role of supportive school environments in associations between adverse childhood experiences (ACEs) and nonsuicidal self-injury (NSSI) suicidality among adolescents are lacking. Objective To assess ACEs with NSSI examine modifying such associations. Design, Setting, Participants Using data from 2021 School-Based Chinese Adolescents Health Survey, this cross-sectional study includes grades 7 through 12 326 schools across 8 provinces China. Statistical analysis was performed March to October 2024. Exposure ACEs, including individual indicators cumulative numbers by total categorized as threat-related deprivation-related were assessed. Main Outcome Measures NSSI, suicidal ideation, suicide attempts measured using validated questionnaires. Weighted Poisson regression models used. The interaction assessed multiplicative interactions. Results Among 95 549 included (mean [SD] age, 14.9 [1.8] years; 47 617 males [49.8%]), 45 236 individuals (47.3%) had experienced at least 1 ACE. Compared no those who 4 or more an increased risk (prevalence ratio [PR], 1.31; 95% CI, 1.30-1.33) (ideation: PR, 1.41; 1.39-1.42; attempts: 1.25; 1.24-1.27) after adjusting for covariates, environments. A dose-response association observed number (eg, NSSI: 1.06; 1.05-1.06 exposure vs 0 ACEs; 1.10; 1.10-1.11 2 ACEs). highest PRs found physical abuse, emotional bullying) ≥2 ACEs: 1.28; 1.27-1.29 NSSI; 1.33; CI 1.32-1.34 ideation; 1.18; 1.17-1.19 attempts). All ACE positively associated suicidality, particularly high abuse 1.26; 1.24-1.27 NSSI). Additionally, significantly modified 0.81; 0.76-0.88). Conclusion relevance In study, increases independent environments, but could modify detrimental outcomes. These findings underscore importance enhancing prevent have ACEs.

Language: Английский

Stress and cardiovascular disease: an update DOI
Viola Vaccarino, J. Douglas Bremner

Nature Reviews Cardiology, Journal Year: 2024, Volume and Issue: 21(9), P. 603 - 616

Published: May 2, 2024

Language: Английский

Citations

27
Outdoor artificial light at night and incident cardiovascular disease in adults: A national cohort study across China DOI
Xiangming Hu,

Le-Bing Wang,

Bin Jalaludin

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 918, P. 170685 - 170685

Published: Feb. 3, 2024

Language: Английский

Citations

8
Association of childhood maltreatment and adverse lifetime experiences with post-injury psychopathology: evidence from the China Severe Trauma Cohort DOI Creative Commons

Shu Wen,

Yu Zeng,

Yueyao Xu

et al.

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 21, 2025

Adverse life experiences have been associated with increased susceptibilities to psychopathology in later life. However, their impact on psychological responses following physical trauma remains largely unexplored. Based the China Severe Trauma Cohort, we conducted a cohort study of 2937 patients who were admitted Medical Center West Hospital between June 2020 and August 2023. experiences, including childhood maltreatment (5 subtypes, measured by Childhood Questionnaire-Short Form) adverse lifetime (17 Life Events Checklist) assessed. Generalized linear mixed models used examine associations symptoms at multiple time-points after index injury (i.e., recruitment, 1-, 3-, 6-, 12-month follow-ups), adjusted for important confounders. We further stratified analyses level genetic predisposition given symptom quantified polygenic risk score (PRS) based publicly available GWAS summary statistics. Mediation performed assess role connecting post-injury psychopathology. The mean age participants was 47.95 years predominance males (61.39%). During whole follow-up period, incidence stress-related disorders, anxiety, depression 13.86%, 29.89%, 36.57%, respectively. observed cumulative number those studied adversities psychopathology, particularly disorder (odds ratio [OR] = 2.78, 95% confidence interval [CI] 1.87–4.12 ≥ 2 vs no maltreatment; 2.65 [1.67–4.20] 4 0–1 experiences). By subtype, positive most adversities, pronounced estimates emotional abuse (ORs 1.71–2.52) life-threatening illness/injury 1.87–2.89). found basically comparable among traumatized individuals different PRSs Moreover, may partially (mediation proportion: 22.52–27.48%) explain various Both irrespective susceptibility. Such findings highlight importance close surveillance timely interventions experiences.

Language: Английский

Citations

0
Adversité et cardiologie : la violence infantile : une bombe à retardement DOI

Jean-Pierre Houppe

Archives des Maladies du Coeur et des Vaisseaux - Pratique, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Citations

0
The Relationship Between Self-Reported Adverse Experiences and Depressive Symptoms Among Middle-Aged and Elderly Individuals: A Longitudinal Study Based on the CHARLS Database DOI Creative Commons

Feng Jiang,

Xiuru Guan, Zhixin Zhu

et al.

Brain Behavior & Immunity - Health, Journal Year: 2025, Volume and Issue: unknown, P. 101001 - 101001

Published: April 1, 2025

Language: Английский

Citations

0
The association between patterns of exposure to adverse life events and the risk of chronic kidney disease: a prospective cohort study of 140,997 individuals DOI Creative Commons
Chunyang Li,

Jie Chen,

Yilong Chen

et al.

Translational Psychiatry, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 7, 2024

Exposure to adverse life events is linked somatic disorders. The study aims evaluate the association between at varying stages and risk of chronic kidney disease (CKD), a condition affecting about 10% population worldwide. This prospective cohort included 140,997 participants from UK Biobank. Using survey items related childhood maltreatment, adulthood adversity catastrophic trauma, we performed latent class analysis summarize five distinct patterns exposure events, namely "low-level exposure", "childhood "adulthood "sexual abuse" "child-to-adulthood exposure". We used Cox proportional hazard regression with CKD, regression-based mediation decompose total effect, gene-environment-wide interaction (GEWIS) identify interactions genetic loci events. During median follow-up 5.98 years, 2734 cases incident CKD were identified. Compared exposure" pattern, was associated increased (hazard ratio 1.37, 95% CI 1.14 1.65). BMI, smoking hypertension mediated 11.45%, 9.79%, 4.50% this respectively. Other did not show significant results. GEWIS subsequent analyses indicated that magnitude differed according polymorphisms, identified potential underlying pathways (e.g., interleukin 1 receptor activity). These findings underscore importance incorporating an individual's psychological encounters profiles into precision prevention CKD.

Language: Английский

Citations

3
The association between adverse experiences and longitudinal allostatic load changes with the depression symptoms trajectories in middle-aged and older adults in China: A longitudinal study DOI
Xiujuan Li, M. Y. Dong,

Wenjing Xia

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

2
Childhood Exposure to Interparental Physical Violence and Adult Cardiovascular Disease DOI Creative Commons
Cancan Cui, Lin Liu, Haibin Li

et al.

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(12), P. e2451806 - e2451806

Published: Dec. 20, 2024

Importance Childhood adverse experiences have been linked with long-term risk of cardiovascular disease (CVD), yet the transgenerational associations between interparental behaviors and CVD remain poorly understood. Objectives To explore association exposure to childhood physical violence subsequent examine whether is modified by adult depressive symptoms. Design, Setting, Participants This population-based cohort study included data from China Health Retirement Longitudinal Study (CHARLS), an ongoing recruiting individuals aged 45 years or older, dated June 1, 2011, December 31, 2020, a follow-up duration 9 years. The were analyzed October 2023, May 10, 2024. Exposures An early life questionnaire information on frequency witnessing was administered. Depressive symptoms assessed via validated 10-item Center for Epidemiologic Studies Depression Scale. Main Outcomes Measures outcome measures self-reported physician-diagnosed heart (defined as myocardial infarction, angina, coronary disease, failure, other problems) stroke. Multivariate Cox proportional hazards regression models using attained age time scale conducted. Results Of 10 424 participants, mean (SD) 58.1 (9.0) years, 5332 (51.2%) female, 872 (8.4%) reported violence. Exposure associated increased risks adult-onset (hazard ratio [HR], 1.36; 95% CI, 1.20-1.55), (HR, 1.17-1.57), stroke 1.28; 1.03-1.61). exposed had greater prevalence (2371 9335 participants [25.4%]), which mediated 11.0% 1.26; 1.09-1.45). Conclusions Relevance In this study, higher CVD, partially findings emphasize need comprehensive strategies policy efforts that address social determinants provide household education opportunities.

Language: Английский

Citations

2
Investigating child-facing practitioners’ understanding of adversity and its impact on children’s development and service provision DOI Creative Commons

Emily Smout,

Hadassah Buechner,

Rosie Lynch

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(20), P. e38908 - e38908

Published: Oct. 1, 2024

Highlights•Childhood adversity can have a long-term impact on mental and physical health.•Inconsistency of identifying childhood by professionals across sectors.•Professionals could benefit from training related to its impact.•Public services need support families mitigate the adversity.AbstractAdversity during is common risk factor for poorer outcomes physical, mental, social health. Despite growing evidence policy around preventing sequalae, incidence in remains high. Child-facing practitioners (CfPs) may be well placed identify address children. This study investigated understanding current practice CfPs working Education system, Healthcare Social Care England. An anonymous online survey was completed 113 between April June 2022. Data analysed using descriptive statistics. Participating CfPs' reported range assessment tools direct observation, but there lack consistency extent which different types were explored assessments. system only liaising with when worker known involved family, or make referral. Indeed, quarter respondents considered early life experiences capacity allowed. Over half this did not know agree that public offer interventions experiencing domestic abuse, parental health difficulties addiction, these adversities children's wellbeing. The highlights further about prevalence inform service delivery. A review routine assessments needed ensure exposure routinely identified; will facilitate access appropriate such experiences.

Language: Английский

Citations

0
Associations of adverse childhood and adulthood experiences with depressive and anxiety symptoms among rural left-behind women: a cross-sectional study in China DOI Creative Commons

Shiyi Shan,

Yuanfei Liu, Leying Hou

et al.

SSM - Mental Health, Journal Year: 2024, Volume and Issue: unknown, P. 100380 - 100380

Published: Dec. 1, 2024

Language: Английский

Citations

0