BMC Endocrine Disorders, Journal Year: 2024, Volume and Issue: 24(1)
Published: Oct. 25, 2024
Research on the relationship between dietary phytochemical intake and anthropometric indices as well diabetic foot ulcers (DFUs) remains inconsistent. We aimed to investigate associations of index (DPI) with novel severity DFUs.
Language: Английский
Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16
Published: Jan. 27, 2025
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic clinical condition characterized by pathological and physiological interactions among metabolic abnormalities, chronic kidney disease, cardiovascular diseases, leading to multi-organ dysfunction higher incidence of endpoints. Traditional approaches managing CKM risk are inadequate in these patients, necessitating strategies targeting specific factors. Increasing evidence suggests that addressing uremic toxins and/or pathways induced may reduce treat the disease. This review explores heart, kidney, context underscores significant role as potential therapeutic targets pathophysiology diseases. Strategies aimed at regulating offer avenues for reversing syndrome, providing new insights its diagnosis treatment.
Language: Английский
Citations
1
BMC Nutrition, Journal Year: 2025, Volume and Issue: 11(1)
Published: April 2, 2025
Diabetic microvascular complications, including diabetic retinopathy (DR), nephropathy (DN), and peripheral neuropathy (DPN), contribute significantly to morbidity healthcare burdens among individuals with diabetes. The Mediterranean diet (MD) has been associated improved metabolic health, but its role in mitigating complications remains unclear. This systematic review meta-analysis aimed assess the impact of MD adherence on risk progression these complications. A comprehensive search PubMed, Web Science, Embase, Scopus was conducted through February 12, 2025 identify studies evaluating Meta-analysis performed where possible, effect sizes reported as odds ratios (ORs) or hazard (HRs) 95% confidence intervals (CIs). Fourteen studies, encompassing 138 71,392 participants, were included. indicated a significant reduction DR adhering (HR: 0.69, CI: 0.49-0.97, p = 0.03; OR: 0.32, 0.12-0.82, 0.02). lower likelihood DN development observed 0.85, 0.73-0.99, 0.04; 0.49, 0.25-0.96, 0.04). However, results for inconclusive due study heterogeneity. Sensitivity analyses revealed notable heterogeneity publication bias detected some analyses. Adherence is reduced retinopathy, supporting potential dietary intervention diabetes management. evidence inconclusive. Future well-controlled randomized trials are needed strengthen causal inferences refine clinical recommendations MD-based interventions
Language: Английский
Citations
0
Food & Function, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Diabetic Kidney Disease (DKD) is a common and serious complication of diabetes, particularly Type 2 Diabetes Mellitus (T2DM), which significantly contributes to patient morbidity mortality. The limitations traditional treatments like ACE inhibitors ARBs in managing DKD progression highlight the need for innovative therapeutic strategies. This review examines impact various dietary patterns, such as Mediterranean diet, ketogenic intermittent fasting, DASH vegetarian on management DKD. Evidence suggests these diets can halt DKD, although further research needed confirm their long-term effectiveness safety. Personalized approaches tailored individual needs may enhance outcomes patients.
Language: Английский
Citations
0
BMC Endocrine Disorders, Journal Year: 2024, Volume and Issue: 24(1)
Published: Oct. 25, 2024
Research on the relationship between dietary phytochemical intake and anthropometric indices as well diabetic foot ulcers (DFUs) remains inconsistent. We aimed to investigate associations of index (DPI) with novel severity DFUs.
Language: Английский
Citations
0