Associations of the planetary health diet index (PHDI) with asthma: the mediating role of body mass index

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Aug. 26, 2024

Given the global shifts in environmental conditions and dietary habits, understanding potential impact of factors body mass index (BMI) on respiratory diseases, including asthma, is paramount. Investigating these relationships can contribute to formulation more effective prevention strategies. The Planetary Health Diet Index (PHDI), a scoring system that balances human health with sustainability, underscores importance increasing consumption plant-based foods while reducing intake red meat, sugar, highly processed foods. objective this study was assess association between PHDI prevalence asthma mediation effect BMI US general population. This utilized data from 32,388 participants National Nutrition Examination Survey (NHANES) spanning 2005 2018. Multivariate logistic regression weighted quantile sum (WQS) regressions were employed investigate PHDI, individual nutrients, asthma. Restricted cubic spline (RCS) analysis explored linear or non-linear relationship Interaction analyses conducted subgroups validate findings. Mediation performed examine There significant negative After adjusting for covariates, every 10-point increase there 4% decrease (P = 0.025). Moreover, as increased, trend towards lower < 0.05). WQS showed consistent associations (OR 0.93, 95%CI: 0.88, 0.98), Fiber, Vitamin C, Protein factors. dose-response curve indicated higher associated prevalence. Additionally, significantly positively 0.001), decreases increases (β -0.64, P 0.001). indicates mediates proportion 33.85% results show strong correlation In addition, mediated relationship.

Language: Английский

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The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001–2018

BMC Cancer, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 23, 2025

Oxidative stress is a crucial pathophysiological mechanism in chronic diseases and mortality. While individual oxidative markers have been studied, the comprehensive impact of balance on mortality risks remains unclear, particularly among cancer survivors. We aimed to investigate associations Balance Score (OBS) with both general population This study included 37,317 adults (52% female) from National Health Nutrition Examination Survey (2001-2018). OBS was calculated based antioxidant pro-oxidant exposures categorized into quartiles. Survey-weighted Cox proportional hazards models were used estimate hazard ratios for risks. Restricted cubic spline analyses performed examine potential non-linear relationships. Stratified conducted further refine findings. During mean follow-up 9.1 years, 5,092 deaths occurred. Compared lowest quartile, highest quartile total associated lower all-cause (HR 0.68) 0.55). Among survivors, similar observed 0.66). Component analysis revealed consistent protective effects 0.60 mortality), while higher showed varying across causes. Higher risks, cancer-related mortality, effects, varied by

Language: Английский

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Overview of MitoQ on prevention and management of cardiometabolic diseases: a scoping review

Frontiers in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 12

Published: March 11, 2025

Background The exploration of mitochondrial-targeted antioxidants represented a burgeoning field research with significant implications for cardiometabolic diseases (CMD). studies reviewed in this scoping analysis collectively highlighted the effect MitoQ on prevention and management CMD underlying mechanisms were discussed, mainly including cardiovascular (CVDs), liver health others. Methods This review aimed to synthesize current impacts CMD, focusing primarily human-based clinical trials. While primary focus was human trials, vivo vitro referenced as supplementary material provide broader understanding MitoQ's potential effects. Results had synthesized findings that contributed their role CMD. Conclusion synthesis these illustrated broad spectrum benefits ranging from enhanced insulin secretion improved lipid profiles mitochondrial function, yet path application required further investigation appropriate doses populations.

Language: Английский

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Association of the dietary index for gut microbiota with sleep disorder among US adults: the mediation effect of dietary inflammation index

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 17, 2025

Previous studies have confirmed the relationship between gut microbiota and sleep disorders, characterized by persistent inability to achieve adequate sleep, with dietary composition playing a key role in maintaining homeostasis. Our study aims explore newly proposed Dietary Index for Gut Microbiota (DI-GM) as well whether Inflammatory (DII) mediates this relationship. This is based on data from 30,406 participants National Health Nutrition Examination Survey (NHANES) 2005 2018, cross-sectional survey that represents U.S. adult population. We used multivariable logistic regression models examine DI-GM disorders. Subgroup interaction analyses were conducted assess stability of results. Mediation analysis was employed effect The score significantly negatively correlated After adjusting covariates, each unit increase associated 5% reduction prevalence disorders (p < 0.001). Additionally, there trend toward decrease increasing (trend p 0.05). Dose-response curve revealed linear higher scores being lower DII positively 0.001) decreased increased (β = -0.37, showed mediated mediation proportion 27.36% results indicate A incidence while Specifically, an may attenuate protective

Language: Английский

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The association between frailty index and abdominal aortic calcification in the middle-aged and older US adults: NHANES 2013–2014

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: May 7, 2025

Abdominal aortic calcification (AAC) is one of the earliest observed forms atherosclerotic and crucial for early cardiovascular risk prediction. Frailty, a global clinical public health challenge, associated with increased risks mortality, functional decline, loss independence. However, relationship between Frailty Index (FI) AAC among middle-aged older adults has yet to be explored. This study analyzed data from 2013 2014 National Health Nutrition Examination Survey (NHANES) cohort, focusing on individuals aged ≥ 40 years. The FI was calculated using 49-item model assess frailty status participants were stratified into three groups: non-frail (FI ≤ 0.15), pre-frail (0.15 < 0.25), frail > 0.25). measured by dual-energy X-ray absorptiometry quantified Kauppila scores. Severe defined as an score 6. investigated multivariable logistic regression, sensitivity analyses, smoothing curve fitting. Subgroup analyses interaction tests conducted stability this association across different populations. A total 2,572 enrolled in study. Following adjustment potential confounders, exhibited statistically significant positive both (β = 2.64, 95%CI 1.20-4.08) (OR 6.36, 1.48-27.41). Similar trends (P trend 0.05) when categorical variable. Smooth fitting subgroup analysis used investigate baseline Z-score AAC. Interestingly, we found that linearly related occurrence severe AAC, while it nonlinearly score. FI-Z positively likelihood before breakpoint (K 0.78), but not after breakpoint. stable subgroups (all P 0.05). Our indicated correlation may serve biomarker subclinical atherosclerosis detection US adults.

Language: Английский

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Association of Dietary Inflammation Index with sarcopenia in adult women with nonalcoholic fatty liver disease: based on the National Health and Nutrition Examination Survey Database

European Journal of Gastroenterology & Hepatology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Background A higher Dietary Inflammatory Index (DII) is linked with an elevated risk of sarcopenia, but the relationship between two in adult female patients nonalcoholic fatty liver disease (NAFLD) remains uncertain. Objective The project was designed to probe into DII and sarcopenia NAFLD patients. Methods As a cross-sectional study, this study used data for women from 2017 2018 National Health Nutrition Examination Survey (NHANES) Database, as independent variable dependent variable. examined by utilizing weighted logistic regression. Restricted cubic splines (RCS) threshold effect models were further employed explore nonlinear two. Results We included 469 patients, whom 65 (10.2%) sarcopenic. In great positive correlation observed logistics regression model [odds ratio (OR): 1.459, 95% confidence interval (CI): 1.013–2.103, P = 0.045]. RCS curve manifested linear ( 0.751). analysis demonstrated that when > 0, positively (OR: 1.328, CI: 1.030–1.722, 0.030). Conclusion sarcopenia. Future research should mechanism influence on evaluate whether improving eating habits can effectively reduce occurrence NAFLD.

Language: Английский

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