Diabetes mellitus and glymphatic dysfunction: Roles for oxidative stress, mitochondria, circadian rhythm, artificial intelligence, and imaging DOI Open Access
Kenneth Maiese

World Journal of Diabetes, Journal Year: 2024, Volume and Issue: 16(1)

Published: Nov. 29, 2024

Diabetes mellitus (DM) is a debilitating disorder that impacts all systems of the body and has been increasing in prevalence throughout globe. DM represents significant clinical challenge to care for individuals prevent onset chronic disability ultimately death. Underlying cellular mechanisms development are multi-factorial origin involve pathways associated with production reactive oxygen species generation oxidative stress as well dysfunction mitochondrial organelles, programmed cell death, circadian rhythm impairments. These can failure glymphatic pathway brain linked rhythms disorders during loss metabolic homeostasis. New studies incorporate number promising techniques examine patients include machine learning artificial intelligence potentially predict dysfunction.

Language: Английский

Diabetes mellitus and glymphatic dysfunction: Roles for oxidative stress, mitochondria, circadian rhythm, artificial intelligence, and imaging DOI Open Access
Kenneth Maiese

World Journal of Diabetes, Journal Year: 2024, Volume and Issue: 16(1)

Published: Nov. 29, 2024

Diabetes mellitus (DM) is a debilitating disorder that impacts all systems of the body and has been increasing in prevalence throughout globe. DM represents significant clinical challenge to care for individuals prevent onset chronic disability ultimately death. Underlying cellular mechanisms development are multi-factorial origin involve pathways associated with production reactive oxygen species generation oxidative stress as well dysfunction mitochondrial organelles, programmed cell death, circadian rhythm impairments. These can failure glymphatic pathway brain linked rhythms disorders during loss metabolic homeostasis. New studies incorporate number promising techniques examine patients include machine learning artificial intelligence potentially predict dysfunction.

Language: Английский

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