Vitamin D Status and Incidence of SARS-CoV-2 Reinfections in the Borriana COVID-19 Cohort: A Population-Based Prospective Cohort Study DOI Creative Commons

Salvador Domènech-Montoliu,

Laura López-Diago,

Isabel Aleixandre-Górriz

et al.

Tropical Medicine and Infectious Disease, Journal Year: 2025, Volume and Issue: 10(4), P. 98 - 98

Published: April 6, 2025

A deficient vitamin D (VitD) status has been associated with SARS-CoV-2 infections, severity, and mortality. However, this related to reinfections studied little. Our aim was quantify the risk of considering VitD before reinfection. We performed a population-based prospective cohort study in Borriana (Valencia Community, Spain) during 2020-2023, measuring 25-hydroxyvitamin [25(OH)D] levels by electrochemiluminescence. Cox proportional hazards models were employed. Of total 644 cases confirmed laboratory tests, 378 (58.9%) included our study, an average age 38.8 years; 241 females (63.8%), 127 occurred (33.6%). reinfection incidence rates per 1000 person-days 0.50 for (<20 ng/mL), insufficient (20-29 0.37 sufficient (≥30 ng/mL). Compared status, adjusted hazard ratios 1.79 (95% confidence interval [CI] 0.89-3.59) 1.59 CI 1.06-2.38) significant inverse dose-response (p = 0.02). These results can help improve nutritional actions against reinfections. suggest that lower than 30 ng/mL showed higher Achieving maintaining is recommended prevent

Language: Английский

Vitamin D Status and Incidence of SARS-CoV-2 Reinfections in the Borriana COVID-19 Cohort: A Population-Based Prospective Cohort Study DOI Creative Commons

Salvador Domènech-Montoliu,

Laura López-Diago,

Isabel Aleixandre-Górriz

et al.

Tropical Medicine and Infectious Disease, Journal Year: 2025, Volume and Issue: 10(4), P. 98 - 98

Published: April 6, 2025

A deficient vitamin D (VitD) status has been associated with SARS-CoV-2 infections, severity, and mortality. However, this related to reinfections studied little. Our aim was quantify the risk of considering VitD before reinfection. We performed a population-based prospective cohort study in Borriana (Valencia Community, Spain) during 2020-2023, measuring 25-hydroxyvitamin [25(OH)D] levels by electrochemiluminescence. Cox proportional hazards models were employed. Of total 644 cases confirmed laboratory tests, 378 (58.9%) included our study, an average age 38.8 years; 241 females (63.8%), 127 occurred (33.6%). reinfection incidence rates per 1000 person-days 0.50 for (<20 ng/mL), insufficient (20-29 0.37 sufficient (≥30 ng/mL). Compared status, adjusted hazard ratios 1.79 (95% confidence interval [CI] 0.89-3.59) 1.59 CI 1.06-2.38) significant inverse dose-response (p = 0.02). These results can help improve nutritional actions against reinfections. suggest that lower than 30 ng/mL showed higher Achieving maintaining is recommended prevent

Language: Английский

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