Clinical and Applied Thrombosis/Hemostasis, Journal Year: 2024, Volume and Issue: 30
Published: Jan. 1, 2024
This study aimed to investigate the association between triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE).
Language: Английский
Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: Feb. 19, 2025
The atherogenic index of plasma (AIP) is a recent biomarker linked to atherosclerosis that has been validated as novel indicator for myocardial infarction (MI). However, the relationship between AIP and severity coronary artery disease (CAD) in MI patients still ambiguous, particularly among individuals with different glucose metabolic conditions. A total 741 participants who were immediately assessed angiography upon admission diagnosed acute recruited. CAD was based on number narrowed vessels. tertiles used divide into three groups (T1: < 0.030; T2: 0.030 ≤ 0.316; T3: > 0.316). American Diabetes Association's guidelines define types state: diabetes mellitus (DM), prediabetes (Pre-DM), normal regulation (NGR). Logistic regression analysis utilized confirm an association patients. ROC curves employed evaluate diagnostic utility In patients, statistically significant correlation found CAD, logistic revealing strong (OR: 2.055; 95% CI: 1.189–3.550; P = 0.009). Following adjustments risk factors model, remained independent predictor multi-vessel 2.902;95% 1.555–5.521 ; 0.001). Moreover, compared T1 group, odds ratios T2 T3 2.039 (95% 1.321–3.175; 0.001) 2.087 1.317–3.340; 0.001), respectively. area under curve predicting 0.568 0.520–0.616; p 0.006). addition, observed increased Pre-DM group. closely associated prediction CAD. clearly whereas this absent NGR DM groups.
Language: Английский
Citations
0
Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16
Published: Feb. 21, 2025
The predictive value of triglyceride-glucose index (TyG) for cardiovascular disease (CVD) in the US elderly diabetic patients is ambiguous. This study aimed to investigate association between TyG and risk CVD an older population with diabetes. examined data from 2007-2016 National Health Nutrition Examination Survey (NHANES). Univariate multivariate regression analysis models were obtained explore baseline CVD. Non-linear investigated using restricted cubic spline (RCS) regression. Subgroup analyses interaction tests constructed a sensitivity was carried out. 10 - year evaluated via Framingham Risk Score (FRS). Mediation explored mediating role glycated hemoglobin above relationships. A total 2987 subjects included (977 2010 non-CVD persons). had higher values (9.01 ± 0.58 vs. 8.94 0.56, P=0.003), prevalence increased (P=0.015). In multifactorial model gradual adjustment all covariates, associated by 48.0% highest quartile group (OR 1.480, 95% Cl 1.171-1.871, P=0.001). RCS curves showed U-shaped (P overall=0.013, P nonlinear=0.043). that group, individuals body mass (BMI) ≥24 kg/m2, estimated glomerular filtration rate (eGFR) <90 mL/1.73m2/min, without chronic kidney disease, those hypertension significantly risks Sensitivity indicated these associations not other significant confounders. Under different models, exhibited correlations (all < 0.05). Glycated mediated sample patients, there risk. implies can be regarded as extremely important predictor screening people at high among patients.
Language: Английский
Citations
0
Journal of Family Medicine and Primary Care, Journal Year: 2025, Volume and Issue: 14(3), P. 1064 - 1068
Published: March 1, 2025
A BSTRACT Objectives: To study the role of triglyceride glucose (TyG) index as a novel biomarker in patients with type 2 diabetes mellitus (T2DM) developing acute coronary syndrome (ACS). Methods: This was cross-sectional, case–control conducted over 1 year sample size 175 T2DM subjects divided into cases and controls at ratio 2:5 (50 cases: ACS, 125 controls: without ACS). The TyG calculated using formula Ln [fasting triglycerides (mg/dL) × fasting plasma (mg (dL)/2]. Result: In this study, nearly half had ST-elevation myocardial infarction male preponderance. significantly higher ACS group. Body mass index, blood sugar, serum cholesterol, urea levels were cases. showed strong correlation linear regression analysis identified it strongest risk factor for these patients, cutoff value 8.9, providing 99% sensitivity specificity. Interestingly, high-sensitivity CRP not different between two groups. Conclusion: derived from glucose, is simple cost-effective marker insulin resistance (IR) cardiovascular risks. It comparable to other markers predicting conditions such artery disease (CAD) atherosclerosis can be incorporated routine clinical evaluation predict which remains leading cause morbidity mortality T2DM.
Language: Английский
Citations
0
Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16
Published: April 17, 2025
Background This study compares the association of eight insulin resistance (IR)-related markers (triglyceride-glucose index (TyG), TyG-body mass (TyG-BMI), TyG-waist circumference (TyG-WC), TyG-waist-to-height ratio (TyG-WHtR), triglycerides-to-high-density lipoprotein cholesterol (TG/HDL), lipid accumulation product (LAP), visceral adiposity (VAI), and estimated glucose disposal rate (eGDR)) with cardiovascular disease (CVD). Methods Spearman’s coefficients were used for correlations between IR-related markers. Predictive capacities evaluated using receiver operating characteristic (ROC) curve analysis, Akaike Information Criterion, Bayesian Criterion calculated. Multivariable-adjusted Cox regression models restricted cubic spline (RCS) analysis performed to explore associations CVD. Results In Pearson correlation TyG-WC TyG-WHtR had a coefficient 0.95, while TG/HDL VAI 0.97. Regarding predictive capacity across different glycemic states, eGDR showed best performance among 8 markers, particularly in predicting stroke. According each unit increase TyG, TyG-BMI, TyG-WC, TyG-WHtR, risk heart increased by 24.1%, 0.4%, 0.1%, 17.56%, respectively; stroke 69.3%, 0.6%, 0.2%, 36.5%, respectively. Additionally, ratio, VAI, LAP exhibited nonlinear risk. For eGDR, risks decreased 21% 14.2%, respectively Conclusion is most effective marker CVD, especially stroke, all states. Modified TyG indices provide better value than alone.
Language: Английский
Citations
0
Diagnostics, Journal Year: 2024, Volume and Issue: 14(20), P. 2261 - 2261
Published: Oct. 11, 2024
We aimed to investigate the association between triglyceride glucose index (TGI) and mortality in patients with ST-elevation myocardial infarction (STEMI).
Language: Английский
Citations
2
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(23), P. 7003 - 7003
Published: Nov. 21, 2024
This study aimed to investigate the impact of RDW-albumin ratio (RAR), Triglyceride-glucose index (TGI), and pan-immune-inflammation value (PIV) on predicting prognosis in patients with coronary artery disease (CAD) assess potential use these biomarkers clinical decision-making.
Language: Английский
Citations
1
Acta Cardiologica, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 2
Published: Nov. 26, 2024
Language: Английский
Citations
1
Diabetology & Metabolic Syndrome, Journal Year: 2024, Volume and Issue: 16(1)
Published: Sept. 28, 2024
Language: Английский
Citations
0
Clinical and Applied Thrombosis/Hemostasis, Journal Year: 2024, Volume and Issue: 30
Published: Jan. 1, 2024
This study aimed to investigate the association between triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE).
Language: Английский
Citations
0