Stress hyperglycemia ratio: a novel prognostic marker in chronic kidney disease DOI Creative Commons

Tianquan Chen,

Yuanqiang Zhu,

Yushuang Liu

et al.

Diabetology & Metabolic Syndrome, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 25, 2025

The stress hyperglycemia ratio (SHR) has recently been suggested to characterize acute glycemic rise better than the admission blood glucose and be associated with unfavorable outcomes in patients various cardiovascular diseases. This study aimed explore associations between SHR all-cause or disease (CVD) mortality chronic kidney (CKD). Adults CKD participating 1999–2018 US National Health Nutrition Examination Survey complete follow-up data were included. was calculated from fasting glycated hemoglobin levels. Associations investigated by weighted multivariable Cox regression analysis. Among 3284 participants (mean age 61 years, men prevalence 44.09%) included, 1324 (487 CVD-related) deaths occurred during a median of 87 months. restricted cubic spline curve adjusted for all covariates showed U-shaped J-shaped association CVD mortality, respectively, discernible inflection points at 0.86 0.88, respectively. hazard (95% confidence interval) 0.117 (0.034–0.404) < 2.065 (1.328–3.209) ≥ 0.063 (0.008–0.531) 0.88 1.551 (0.770–3.124) mortality. We identified CKD. result highlights that may potentially informative risk stratification patients. Given potential limitations residual confounding, prospective studies are needed confirm our findings.

Language: Английский

Stress hyperglycemia ratio: a novel prognostic marker in chronic kidney disease DOI Creative Commons

Tianquan Chen,

Yuanqiang Zhu,

Yushuang Liu

et al.

Diabetology & Metabolic Syndrome, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 25, 2025

The stress hyperglycemia ratio (SHR) has recently been suggested to characterize acute glycemic rise better than the admission blood glucose and be associated with unfavorable outcomes in patients various cardiovascular diseases. This study aimed explore associations between SHR all-cause or disease (CVD) mortality chronic kidney (CKD). Adults CKD participating 1999–2018 US National Health Nutrition Examination Survey complete follow-up data were included. was calculated from fasting glycated hemoglobin levels. Associations investigated by weighted multivariable Cox regression analysis. Among 3284 participants (mean age 61 years, men prevalence 44.09%) included, 1324 (487 CVD-related) deaths occurred during a median of 87 months. restricted cubic spline curve adjusted for all covariates showed U-shaped J-shaped association CVD mortality, respectively, discernible inflection points at 0.86 0.88, respectively. hazard (95% confidence interval) 0.117 (0.034–0.404) < 2.065 (1.328–3.209) ≥ 0.063 (0.008–0.531) 0.88 1.551 (0.770–3.124) mortality. We identified CKD. result highlights that may potentially informative risk stratification patients. Given potential limitations residual confounding, prospective studies are needed confirm our findings.

Language: Английский

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