Evaluating the Prognostic Value of the Triglyceride–Glucose Index in Different Populations: A Critical Analysis DOI Open Access
Antonio E. Pontiroli, Lucia La Sala, Elena Tagliabue

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(7), P. 1124 - 1124

Published: March 24, 2025

Background/Objectives: Recent studies have highlighted the Triglyceride-Glucose Index (TYG) as a significant risk factor for mortality and co-morbidities in various populations, including those with type 2 diabetes mellitus (T2DM) cardiovascular diseases. However, its prognostic role obese individuals remains less clear. Methods: Utilizing data from an cohort of 1359 subjects 1999-2004 cycles National Health Nutrition Examination Survey (NHANES) 15,267 subjects, this study investigates value TYG blood glucose relation to age sex other factors such metabolic syndrome, Charlson Comorbidity Index, T2DM tolerance, predicting among subjects. Over median follow-up about 13 years, 11.3% 20.6% NHANES died. Our findings indicate that while are significantly related mortality, they offer only modest improvements over models incorporating age, sex, showed power 76.1% 86.0% respective cohorts. Conclusions: These results suggest holds potential biomarker, utility beyond established requires further validation clinical settings.

Language: Английский

Evaluating the Prognostic Value of the Triglyceride–Glucose Index in Different Populations: A Critical Analysis DOI Open Access
Antonio E. Pontiroli, Lucia La Sala, Elena Tagliabue

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(7), P. 1124 - 1124

Published: March 24, 2025

Background/Objectives: Recent studies have highlighted the Triglyceride-Glucose Index (TYG) as a significant risk factor for mortality and co-morbidities in various populations, including those with type 2 diabetes mellitus (T2DM) cardiovascular diseases. However, its prognostic role obese individuals remains less clear. Methods: Utilizing data from an cohort of 1359 subjects 1999-2004 cycles National Health Nutrition Examination Survey (NHANES) 15,267 subjects, this study investigates value TYG blood glucose relation to age sex other factors such metabolic syndrome, Charlson Comorbidity Index, T2DM tolerance, predicting among subjects. Over median follow-up about 13 years, 11.3% 20.6% NHANES died. Our findings indicate that while are significantly related mortality, they offer only modest improvements over models incorporating age, sex, showed power 76.1% 86.0% respective cohorts. Conclusions: These results suggest holds potential biomarker, utility beyond established requires further validation clinical settings.

Language: Английский

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