Correlation between the atherogenic index of plasma and risk of diabetic retinopathy DOI Creative Commons
Yuan Zhang, Guanhua Chen,

Yali Jing

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: May 16, 2025

Objective To investigate the relationship between atherogenic index of plasma (AIP) and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods A total 584 T2DM were divided into two groups based on whether DR (non-DR group, n = 382; 202). The association AIP was assessed by Spearman’s correlation bivariate/multivariate logistic regression. Results group showed significantly higher levels than those non-DR (−0.009 ± 0.226 vs. 0.186 0.261, p < 0.001). Compared without DR, had age, systolic blood pressure (SBP), body mass (BMI), duration, triglycerides (TG), urea nitrogen (BUN) creatinine (Cr), while direct bilirubin (DBIL) high-density lipoprotein cholesterol (HDL-C) lower ( 0.05). According to interquartile range AIP, participants four groups: Q1 (≤−0.130), Q2 (−0.129, 0.048), Q3 (0.049, 0.220), Q4 (≥0.221). After adjusting for BMI, SBP, DBIL, BUN Cr, regression model indicated that subjects still a remarkably increased risk (Q3: OR, 2.838, 95% CI: 1.268 ~ 7.067; Q4: 4.414, 1.841 10.097; all provided an AUC value 0.697 (95% 0.652 0.741). Conclusion is associated T2DM, may be potential predictor T2DM.

Language: Английский

Correlation between the atherogenic index of plasma and risk of diabetic retinopathy DOI Creative Commons
Yuan Zhang, Guanhua Chen,

Yali Jing

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: May 16, 2025

Objective To investigate the relationship between atherogenic index of plasma (AIP) and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods A total 584 T2DM were divided into two groups based on whether DR (non-DR group, n = 382; 202). The association AIP was assessed by Spearman’s correlation bivariate/multivariate logistic regression. Results group showed significantly higher levels than those non-DR (−0.009 ± 0.226 vs. 0.186 0.261, p < 0.001). Compared without DR, had age, systolic blood pressure (SBP), body mass (BMI), duration, triglycerides (TG), urea nitrogen (BUN) creatinine (Cr), while direct bilirubin (DBIL) high-density lipoprotein cholesterol (HDL-C) lower ( 0.05). According to interquartile range AIP, participants four groups: Q1 (≤−0.130), Q2 (−0.129, 0.048), Q3 (0.049, 0.220), Q4 (≥0.221). After adjusting for BMI, SBP, DBIL, BUN Cr, regression model indicated that subjects still a remarkably increased risk (Q3: OR, 2.838, 95% CI: 1.268 ~ 7.067; Q4: 4.414, 1.841 10.097; all provided an AUC value 0.697 (95% 0.652 0.741). Conclusion is associated T2DM, may be potential predictor T2DM.

Language: Английский

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