
Cancer Cell International, Journal Year: 2024, Volume and Issue: 24(1)
Published: March 30, 2024
Language: Английский
Cancer Cell International, Journal Year: 2024, Volume and Issue: 24(1)
Published: March 30, 2024
Language: Английский
Cellular Signalling, Journal Year: 2025, Volume and Issue: 127, P. 111605 - 111605
Published: Jan. 20, 2025
Language: Английский
Citations
1Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 17, 2024
Language: Английский
Citations
4Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: 266, P. 155810 - 155810
Published: Jan. 5, 2025
Language: Английский
Citations
0International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3078 - 3078
Published: March 27, 2025
Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality, influenced by both genetic epigenetic factors. Long non-coding RNAs (lncRNAs) such as GAS5 CASC8 have been implicated in susceptibility. This study aimed to assess the association rs145204276 ins/del rs10505477 A>G polymorphisms with CRC risk Romanian population. A case-control was conducted, including 156 patients 195 healthy controls. Genotyping for performed using real-time PCR, evaluated logistic regression calculate odds ratios (OR) 95% confidence intervals (CI). The carriers del allele significantly associated increased (OR: 2.13, CI: 1.24-3.63, p = 0.005) dominant model. In subgroup analysis, polymorphism restricted distal colon cases 2.98, 1.57-5.66, 0.001), advanced tumor stages (III + IV) 2.54, 1.31-4.91, 0.007), poorly differentiated tumors (G3) 3.98, 1.49-10.59, 0.009). No significant correlation found polymorphism. may influence susceptibility, particularly stages. However, showed no this cohort.
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 289, P. 138800 - 138800
Published: Dec. 16, 2024
Language: Английский
Citations
2Cancer Cell International, Journal Year: 2024, Volume and Issue: 24(1)
Published: March 30, 2024
Language: Английский
Citations
1