ACS Nano,
Journal Year:
2021,
Volume and Issue:
15(12), P. 19600 - 19612
Published: Nov. 17, 2021
As
interest
continues
to
grow
in
Ti3C2Tx
and
other
related
MXenes,
advancement
methods
of
manipulation
their
surface
functional
groups
beyond
synthesis-based
terminations
(Tx:
-F,
-OH,
═O)
can
provide
mechanisms
enhance
solution
processability
as
well
produce
improved
solid-state
device
architectures
coatings.
Here,
we
report
a
chemically
important
modification
approach
which
"solvent-like"
polymers,
polyethylene
glycol
carboxylic
acid
(PEG6-COOH),
are
covalently
attached
onto
MXenes
via
esterification
chemistry.
Surface
with
PEG6-COOH
large
ligand
loading
(up
14%
by
mass)
greatly
enhances
dispersibility
wide
range
nonpolar
organic
solvents
(e.g.,
2.88
mg/mL
chloroform)
without
oxidation
two-dimensional
flakes
or
changes
the
structure
ordering.
Furthermore,
cooperative
interactions
between
polymer
chains
improve
nanoscale
assembly
uniform
microstructures
stacked
MXene-PEG6
into
ordered
thin
films
excellent
electrical
conductivity
(∼16,200
S·cm-1).
Most
importantly,
our
covalent
ω-functionalized
PEG6
ligands
(ω-PEG6-COOH,
where
ω:
-NH2,
-N3,
-CH═CH2)
allows
for
control
over
degree
functionalization
(incorporation
valency)
MXene.
We
believe
that
installing
valency
through
short,
ion
conducting
PEG
compromising
MXenes'
features
such
processability,
structural
stability,
further
chemistry
tunability
performance
widens
applications.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(36), P. 47003 - 47049
Published: Aug. 27, 2024
Recently,
two-dimensional
(2-D)
layered
materials
have
revealed
outstanding
properties
and
play
a
crucial
role
for
numerous
advanced
applications.
The
emerging
transition
metal
carbides
nitrides,
known
as
MXene
with
empirical
formula
M
Chemical Society Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Since
their
discovery
over
a
decade
ago,
MXenes
have
transformed
the
field
of
"materials
for
healthcare",
stimulating
growing
interest
in
healthcare-related
applications.
These
developments
also
driven
significant
advancements
MXenes'
synthesis.
This
review
systematically
examines
synthesis
and
applications
sensing
biomedical
fields,
underscoring
pivotal
role
addressing
critical
challenges
modern
healthcare.
We
describe
experimental
by
combining
appropriate
laboratory
modules
with
mechanistic
principles
underlying
each
step.
In
addition,
we
provide
extensive
details
on
parameters,
considerations,
essential
instructions
successful
Various
healthcare
including
sensing,
imaging,
synergistic
therapies,
regenerative
medicine,
wearable
devices
been
explored.
further
highlight
emerging
trends
MXenes,
viz.,
as
nanovehicles
drug
delivery,
vectors
gene
therapy,
tools
immune
profiling.
By
identifying
important
parameters
that
define
utility
applications,
this
outlines
strategies
to
regulate
profile,
thereby
serving
valuable
guide
design
application-specific
properties.
The
final
section
integrates
research
theoretical
studies
comprehensive
understanding
field.
It
technologies,
such
artificial
intelligence
(AI)
machine
learning
(ML),
accelerating
material
discovery,
structure-property
optimization,
automation.
Complemented
detailed
supplementary
information
synthesis,
stability,
biocompatibility,
environmental
impact,
insights,
offers
profound
knowledge
base
diverse
family
2D
materials.
Finally,
compared
potential
other
materials
underscore
existing
prioritize
interdisciplinary
collaboration.
synthesizing
key
from
its
current
(especially
2018
onward),
provides
cohesive
assessment
MXene
foundations
prospects
sector.
ACS Nano,
Journal Year:
2021,
Volume and Issue:
15(12), P. 19600 - 19612
Published: Nov. 17, 2021
As
interest
continues
to
grow
in
Ti3C2Tx
and
other
related
MXenes,
advancement
methods
of
manipulation
their
surface
functional
groups
beyond
synthesis-based
terminations
(Tx:
-F,
-OH,
═O)
can
provide
mechanisms
enhance
solution
processability
as
well
produce
improved
solid-state
device
architectures
coatings.
Here,
we
report
a
chemically
important
modification
approach
which
"solvent-like"
polymers,
polyethylene
glycol
carboxylic
acid
(PEG6-COOH),
are
covalently
attached
onto
MXenes
via
esterification
chemistry.
Surface
with
PEG6-COOH
large
ligand
loading
(up
14%
by
mass)
greatly
enhances
dispersibility
wide
range
nonpolar
organic
solvents
(e.g.,
2.88
mg/mL
chloroform)
without
oxidation
two-dimensional
flakes
or
changes
the
structure
ordering.
Furthermore,
cooperative
interactions
between
polymer
chains
improve
nanoscale
assembly
uniform
microstructures
stacked
MXene-PEG6
into
ordered
thin
films
excellent
electrical
conductivity
(∼16,200
S·cm-1).
Most
importantly,
our
covalent
ω-functionalized
PEG6
ligands
(ω-PEG6-COOH,
where
ω:
-NH2,
-N3,
-CH═CH2)
allows
for
control
over
degree
functionalization
(incorporation
valency)
MXene.
We
believe
that
installing
valency
through
short,
ion
conducting
PEG
compromising
MXenes'
features
such
processability,
structural
stability,
further
chemistry
tunability
performance
widens
applications.
