Role of Nanomedicine in Transforming Pharmacotherapy for Substance Use Disorder (SUD)

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2025, Volume and Issue: 17(2)

Published: March 1, 2025

ABSTRACT The field of nanomedicine offers revolutionary potential to reshape the discovery and development therapeutics for diverse human diseases. However, its application has been limited in improving Substance Use Disorders (SUDs), which represent a profound public health crisis, including major types such as opioid, alcohol, stimulant, cannabis use disorders. Pharmacotherapy, cornerstone SUD management, reduced morbidity, mortality, societal impact addiction, though efficacy ranged from none moderate. Thus, there is unmet need transform pharmacotherapy curb epidemic addiction. This article explores roles nanomedicine‐inspired precision‐targeted drug delivery, sustained release, combination therapies increase therapeutic minimize side effects. Additionally, it discusses innovative mechanisms that align with neurobiological complexities addiction synergistic approaches integrate behavioral interventions, device‐based therapies, emerging modalities immunotherapy neurostimulation. Despite these advancements, barriers treatment accessibility, adherence challenges, inequitable resource distribution persist, particularly underserved populations. By harnessing transformative capabilities integrating into holistic, equitable, personalized care frameworks, this review highlights path forward revolutionize landscape. underscores continued nano‐SUD research strategies alleviate substantial burden on individuals, families, society.

Language: Английский

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Application-driven innovations in nanodevices for next-generation transistors, neuromorphic computing, neural interface and quantum computing

Frontiers in Nanotechnology, Journal Year: 2025, Volume and Issue: 7

Published: April 10, 2025

The demand for aggressive scaling in integrated circuits technology has been a primary driving force behind the rapid advancement of nanotechnology, leading to groundbreaking innovations nanoscience, engineering, and technology. Initially, unique phenomena observed at nanoscale enable innovative applications nanodevices. Now, as our understanding greatly developed, nanodevices are increasingly being leveraged provide solutions growing range applications. In this perspective, several key areas featured that proposed benefit significantly from advancements

Language: Английский

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Recent Advances in Nanomaterials for Neural Applications: Opportunities and Challenges

Nanomedicine, Journal Year: 2023, Volume and Issue: 18(26), P. 1979 - 1994

Published: Nov. 1, 2023

Nanomedicines are promising for delivering drugs to the central nervous system, though their precision is still being improved. Fortifying nanoparticles with vital molecules can interact blood-brain barrier, enabling access brain tissue. This study summarizes recent advances in nanomedicine treat neurological complications. The integration of nanotechnology into cell biology aids cells' interactions. Magnetic microhydrogels have exhibited superior neuron activation compared superparamagnetic iron oxide and hold promise neuropsychiatric disorders. Nanomaterials shown notable results, such as tackling neurodegenerative diseases by hindering harmful protein buildup regulating cellular processes. However, further studies safety effectiveness managing disorders required.

Language: Английский

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A Review of Recent Advancements and Perspectives of Nanotechnology in the Application of Biomedical Imaging and Instrumentation

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(27)

Published: July 12, 2024

Abstract The development of imaging, diagnosis, prognosis and early detection diseases has been greatly impacted by nanotechnology enhancing already existing clinically applicable technologies. With the help their capacity to alter nanoparticles for molecular‐level specificity, tissue‐specific diagnosis is made possible gratitude unique biophysical features that enable contrast augmentation will boost biomedical imaging. prospect multiplexing fact minute changes in nanoparticles’ size or composition can have significant effects on optical, magnetic, electrical capabilities. This article examines nanotechnology's function In this article, fundamentals applications pharmaceutical application microbial surfactants, intelligent drug delivery systems, green metallic nanoparticle manufacturing are all examined. comprising organic (carbon nanotubes, metal oxide liposomes) inorganic (metal oxide, metal) nanoparticles, materials with nanopatterns diagnostics, biosensing, bioimaging devices, along main topics discussion. studies conducted vitro vivo demonstrated different be utilized detect seizures precisely treat them successfully. To decrease toxicity improved target respectively, more synthesis functionalization adaptable nanotechnologies required.

Language: Английский

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Ultrasonication-Assisted Green Synthesis and Physicochemical and Cytotoxic Activity Characterization of Protein-Based Nanoparticles from Moringa oleifera Seeds

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(15), P. 1254 - 1254

Published: July 26, 2024

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