Assessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits DOI Creative Commons
Daniel García, Larissa Eckmann Mingrone, Felipe Eduardo Pinotti

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(3), P. 200 - 200

Published: Feb. 26, 2025

Autografts, allografts, and synthetic bone substitutes are essential in reconstructive orthopedic surgery. Although autografts allografts provide excellent skeletal integration, their use is limited by host morbidity graft acquisition challenges. Synthetic materials like β-tricalcium phosphate (β-TCP) offer promising osseoconductive properties as a potential substitute. This study evaluated the osseointegration of β-TCP ceramic cylinder implants defects rabbits. Eighteen New Zealand rabbits underwent radial diaphysis ostectomy to create critical segmental defect were divided into three groups: Group A received blocks, B allogenous cortical grafts, C without filling. Postoperative assessments included clinical evaluations, radiographs, micro-computed tomography, histology at various time points assess implant resorption. At 120th postoperative day, showed successful integration infection. In contrast, no or resorption implants, exhibited non-union. While demonstrated biocompatibility, it lacked osseoconductivity, likely due low porosity. did not promote consolidation, suggesting that further research on porosity shape needed improve suitability for veterinary

Language: Английский

Assessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits DOI Creative Commons
Daniel García, Larissa Eckmann Mingrone, Felipe Eduardo Pinotti

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(3), P. 200 - 200

Published: Feb. 26, 2025

Autografts, allografts, and synthetic bone substitutes are essential in reconstructive orthopedic surgery. Although autografts allografts provide excellent skeletal integration, their use is limited by host morbidity graft acquisition challenges. Synthetic materials like β-tricalcium phosphate (β-TCP) offer promising osseoconductive properties as a potential substitute. This study evaluated the osseointegration of β-TCP ceramic cylinder implants defects rabbits. Eighteen New Zealand rabbits underwent radial diaphysis ostectomy to create critical segmental defect were divided into three groups: Group A received blocks, B allogenous cortical grafts, C without filling. Postoperative assessments included clinical evaluations, radiographs, micro-computed tomography, histology at various time points assess implant resorption. At 120th postoperative day, showed successful integration infection. In contrast, no or resorption implants, exhibited non-union. While demonstrated biocompatibility, it lacked osseoconductivity, likely due low porosity. did not promote consolidation, suggesting that further research on porosity shape needed improve suitability for veterinary

Language: Английский

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