Predictive Ability of Previous Pain and Disease Conditions on the Presentation of Post‐COVID Pain in a Danish Cohort of Adult COVID‐19 Survivors

European Journal of Pain, Journal Year: 2025, Volume and Issue: 29(5)

Published: April 5, 2025

ABSTRACT Background Even though many post‐COVID pain risk factors have been identified, little is known about the predictive profiles of these for development pain. Methods Data was collected from two separate questionnaires assessing demographics, pre‐existing medical comorbidities, history, and experience. Socioeconomic data COVID‐19 RT‐PCR test results were Danish registries. The study cohort ( n = 68,028) stratified into groups reporting pre‐COVID 9090) no 55,938). Forward‐selection prediction models employed to identify predictor in full (Model 1) with 2) without 3) 58 potential factors. Results Model 1 achieved a 5‐fold cross‐validated AUC (cvAUC) 0.68. Use medication, stress, high income, age, female gender, weight top predictors contributing 97% model performance. 2 (cvAUC 0.69) identified use breathing pain, height, physical activity, as 98.6% 3 0.65) weight, higher education, activity 98.5% Height unique 2, while being income 3. Conclusions highlights important predictors, further research needed describe detail. may apply understanding post‐viral sequelae after other viral infections. Significance Statement explorative investigates ability battery potentially associated This article presents interest survivors will contribute patient that might develop conditions provide first step towards focused clinical research.

Language: Английский

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Cumulative social disadvantage and its impact on long COVID: insights from a U.S. national survey

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 6, 2025

The COVID-19 pandemic has exacerbated health disparities, with long COVID emerging as a major global public challenge. Although clinical risk factors for are well-documented, the cumulative burden of adverse social determinants (SDoH) remains underexplored. This study aims to investigate association between disadvantage and COVID. Using data from 2022 2023 National Health Interview Survey cycles (n = 16,446 U.S.adults), was quantified through 18 SDoH indicators categorized into quartiles. highest quartile represents most disadvantaged individuals. Long defined self-reported symptoms persisting three months or longer. Weighted logistic regression models were used examine association, adjusting demographic variables. Adults in exhibited an increased odds experiencing compared those lowest (AOR 2.52, 95% Cl: 2.13, 2.98). persisted across subgroups, particularly pronounced effects among women non-Hispanic Blacks. Hispanics Whites showed weaker, but still statistically significant. Key contributors included mental difficulties, economic instability, healthcare access barriers. Furthermore, linked fair poor general status individuals highlights positive Addressing systemic inequities integrated strategies is essential mitigate reduce disparities health.

Language: Английский

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Cardiac symptoms in patients 3–6 months after contracting COVID-19– data from the polish STOP-COVID registry

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 9, 2025

Abstract Background Common complaints of long COVID patients are cardiac symptoms such as fatigue, weakness, and a feeling palpitations. The study aimed to investigate the clinical features with persistent cardiological occurring within 3 6 months after COVID-19. Differences in ambulatory blood pressure monitoring (ABPM), Holter ECG (electrocardiogram) Echocardiography between people without were evaluated. We also assessed whether anxiety depression may be implicated outcomes. Materials methods This was retrospective affiliated STOP-COVID registry who attended follow-up visit 3–6 undergoing present performed tests: ABPM, Echocardiography. 504 additionally had GAD-2 (Generalized Anxiety Disorder 2-item) PHQ-2 (Patient Health Questionnaire-2) tests performed. Results analysis included 1080 patients. At least 1 analyzed 586 (54.3%). most common symptom fatigue (38.9%). Comparing or palpitations showed that mean value ventricular extrasystole higher former group ( p = 0.011). symptoms, there differences values 0.022) < 0.001) scales, well percentage responses related risk depression. Conclusion Cardiological among health issues must face contracting People more excessive extrasystoles than these symptoms. Trial registration Our based on medical data COVID-19 treated out-patient basis Polish Long-Covid Cardiovascular (PoLoCOV-CVD) (ClinicalTrials.gov identifier– NCT05018052, date 29.05.2020). Consent conduct obtained from Bioethics Committee District Medical Chamber Lodz (no. KB-0115/2021).

Language: Английский

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Long COVID and Associated Factors Among Chinese Residents Aged 16 Years and Older in Canada: A Cross-Sectional Online Study

Biomedicines, Journal Year: 2025, Volume and Issue: 13(4), P. 953 - 953

Published: April 13, 2025

As the COVID-19 pandemic evolved, long COVID emerged as a significant threat to public health, characterized by one or more persistent symptoms impacting organ systems beyond 12 weeks of infection. Informative research has been derived from assessments among Chinese populace. However, none these studies considered experience residents in Canada. Objectives: We aimed fill this literature gap delineating experience, prevalence, and associated factors sample residing Canada during pandemic. Methods: The present study employed cross-sectional online survey questionnaire distributed Canadian using convenience sampling procedure 22 December 2022 15 February 2023. Respondents were probed for sociodemographic background health-, COVID-, vaccine-related characteristics. Logistic LASSO regression was used model building, multivariate logistic identify with developing COVID. Results: Among 491 eligible participants, 63 (12.83%) reported experiencing mean duration 5.31 (95% CI: 4.06–6.57) months major including difficulty concentrating (21.67%), pain/discomfort (15.00%), well anxiety/depression (8.33%). Our final identified associations between two infections (OR = 23.725, 95% 5.098–110.398, p < 0.0001), very severe/severe 3.177, 1.160–8.702, 0.0246), over-the-counter medicine 2.473, 1.035–5.909, 0.0416), traditional 8.259, 3.016–22.620, 0.0001). Further, we protective effect good/good health status 0.247, 0.112–0.544, 0.0005). Conclusions: Long effected notable proportion prolonged period findings underscore importance preexisting reinfection prevention when managing Moreover, our work indicates an association Chinese.

Language: Английский

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“The dream is that there’s one place you go”: a qualitative study of women’s experiences seeking care from Long COVID clinics in the USA

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: June 13, 2024

Abstract Background Seeking and obtaining effective health care for Long COVID remains a challenge in the USA. Women have particularly been impacted, as they are both at higher risk of developing facing gendered barriers to having symptoms acknowledged. clinics, which provide multidisciplinary coordinated care, emerged potential solution. To date, however, there has little examination U.S. patient experiences with clinics how patients may or not come access clinic. Methods We conducted semi-structured interviews 30 women aged 18 older who had experienced least 3 months, hospitalized acute COVID-19, seen one medical provider about their symptoms. Participants were asked seeking COVID. clinic-related responses analyzed using qualitative framework analysis identify key themes clinics. Results Of women, 43.3% ( n = 13) clinic by affiliated 30.0% 9) explored attempted see but time interview. expressed five concerning from clinics: (1) Access an issue, (2) Clinics stop shop, (3) Not all providers sufficient knowledge, (4) can offer validation (5) Treatment options critical urgent. Conclusions While is significant, findings indicate that ongoing challenges related quality coordination hamper contribute distress among care. Since uniquely positioned framed being place go manage complex symptoms, it wellbeing be properly resourced level complies emerging best practices.

Language: Английский

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Lessons Learned From Characterizing Long COVID Among US Medicare Beneficiaries

Pharmacoepidemiology and Drug Safety, Journal Year: 2025, Volume and Issue: 34(2)

Published: Jan. 22, 2025

To characterize long-term effects of COVID-19 among older adults (aged ≥ 65 years). This retrospective descriptive study utilized Medicare Fee-for-Service beneficiaries' claims to post-COVID condition diagnosis code usage, long COVID (defined as diagnoses made 28 days after an initial diagnosis) incidence, patient demographics, and concurrent diagnoses. During April 1, 2020 May 21, 2022, 193 691 (0.6%) 31 847 927 beneficiaries were diagnosed with conditions using ICD-10-CM codes U09.9 B94.8, regardless prior diagnosis. Post-COVID rate was higher nursing home residents (18.7 per 1000 person-years) than community-dwelling (2.8). Among a diagnosis, 17.5% did not have any U07.1 recorded. there no significant sex, age, or race/ethnicity differences between those (i.e., COVID) without conditions. Certain myopathies interstitial pulmonary disease disproportionately present concurrently compared COVID-19. In this large 32 million beneficiaries, we found approximately 194 000 residents, highlighting the substantial burden in vulnerable population. Community-dwelling less likely seek medical care for events which may suggest severity respiratory detection these populations. Long risk infection be similar across demographic groups.

Language: Английский

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Long COVID challenges in Brazil: an unfinished agenda for the Brazilian Unified National Health System

Cadernos de Saúde Pública, Journal Year: 2024, Volume and Issue: 40(2)

Published: Jan. 1, 2024

The COVID-19 pandemic represented an unprecedented public health and humanitarian crisis in the history of humanity and, from a syndemic perspective, caused unequal long-term direct indirect effects on population combined with political, economic, social, environmental, individual issues 1,2,3 .From first cases 2019 to December 31, 2023, cumulative number global deaths reported World Health Organization (WHO) was impressive, despite underreported cases: almost 774 million people affected, which, more than 38 Brazil (4.9%).In total, 7 including 708,000 (10%) 4,5 .With WHO declaring emergency February 2020, efforts have focused reducing morbidity, measures prevent spread SARS-CoV-2, vaccination infection severe clinical forms, mortality 2,6 .Brazil, response Brazilian Unified National System (SUS, acronym Portuguese), has negative inter-federative articulation coping strategies 1,2 .In addition significant deaths, is recognized as chronic condition high morbidity mortality, being neglected by governments, researchers, professionals, society general, affected 2,6,7,8,9,10,11 .This syndrome initially called "long COVID" patients strong social media engagement mobilization advocacy strategies.The idea raise awareness give visibility emerging problem 3,8,9,11,12 .The officially it August 2020 13 , defined "post-COVID-19 condition" probable or confirmed SARS-CoV-2 infection, usually persistent signs/symptoms three months after lasting at least two months, which are not explained another diagnosis 8,12,13 .Other names found literature, specific definitions but limited consensus: "post-COVID syndrome" (National Institute for Care Excellence/United Kingdom), conditions" (Centers Disease Control Prevention/United States), "persistent symptoms consequences COVID-19", "post-acute sequelae SARS CoV-2 infection" 3,8,12 .

Language: Английский

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Long COVID among Brazilian Adults and Elders 12 Months after Hospital Discharge: A Population-Based Cohort Study

Healthcare, Journal Year: 2024, Volume and Issue: 12(14), P. 1443 - 1443

Published: July 19, 2024

The persistence of symptoms for more than three months following infection with severe acute respiratory syndrome coronavirus 2 is referred to as “Long COVID”. To gain a deeper understanding the etiology and long-term progression symptoms, this study aims analyze prevalence Long COVID its associated factors in cohort Brazilian adults elders, twelve after hospital discharge. An observational, prospective, follow-up was performed older diagnosed COVID-19 2020 State Paraná, Brazil. Twelve discharge, patients answered phone questionnaire about levels exposure COVID-19’s phase (ambulatory, medical ward, intensive care unit). According characteristics participants, calculated, logistic regression analyses were conducted. We analyzed data from 1822 participants (980 [≥18–<60 years] 842 people [≥60 years]) across levels. overall 64.2%. observed 646 (55%; which 326 women) 523 (45%; 284 women). Females had higher (52%) compared men. most common post-COVID-19 conditions 12-month neurological (49.8%), followed by musculoskeletal (35.1%) persistent (26.5%). Male individuals less likely develop (aOR = 0.50). Other determinants also considered risky, such presence comorbidities 1.41). Being an adult having been hospitalized development COVID. risk developing twice high ward 2.53) times ICU 3.56) when non-hospitalized patients. Presenting clinical manifestations digestive 1.56), endocrine 2.14), cutaneous 2.51), 2.76) psychological systems 1.66) made present large proportion affected SARS-CoV-2 infection. Presence displayed dose–response relationship level disease exposure, greater form period.

Language: Английский

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Toward the emancipation of “medically unexplained” and energy-limiting conditions: Contesting and reimagining psy through the lens of feminist disability studies

Feminism & Psychology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 10, 2024

Indictment of hegemonic psy construction the “ideal” subject, and its marginalisation Other, is common to both feminism (critical, feminist) disability studies. However, feminist literature largely lacks an appreciation gendered, intersectional nature as constituted propagated by psy, exploration how integrating a category analysis can strengthen critical endeavours transform psy. This article seeks address this gap, espousing studies lens taking subject energy-limiting chronic illnesses that are socially clinically othered, notably via strategic positioning these medically unexplained recoverable through compliance with knowledge regimes. After discussing power-laden dis/abled, more fully constructions idealised bolstered psy–corporate–state agendas relating welfare reform, have oppressively shaped dominant representations practices in arena, I consider (chiefly, psychotherapy) might benefit from thinking within conclude help emancipatory direction reimagining socioculturally biopolitically cognisant, embodied, maximally inclusive manner. The case “medically unexplained” illness exemplifies assertion.

Language: Английский

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A multidisciplinary approach to assessment and management of long COVID cognitive concerns

Life Sciences, Journal Year: 2024, Volume and Issue: 357, P. 123068 - 123068

Published: Sept. 18, 2024

Language: Английский

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