Farming in PFAS-Contaminated Areas: An Ethnographic Exploration within the Veneto Region DOI Creative Commons
Giorgia De Lorenzi

Archivio antropologico mediterraneo, Journal Year: 2024, Volume and Issue: 26(2)

Published: Jan. 1, 2024

This article explores the results of an ethnographic investigation carried out between November 2022 and March 2023, within agricultural sector in highly PFAS-contaminated areas Veneto region, Italy. In order to understand how farmers experienced contamination what they think about their experiences, field research semi-structured interviews were conducted. absence any institutional support clear regulations, laissez-faire approach has accentuated individual accountability, leaving alone deal with these chemical compounds. Considering this context, precarity farming sector, a main feature socioecological context contamination, along fractures silence resulting from are analyzed.

Language: Английский

Persistent organic pollutant perfluorooctanoic acid induces alterations in epigenetic modifications of DNA and RNA DOI

Shu-Yi Gu,

Tian Feng,

Fang‐Yin Gang

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110957 - 110957

Published: Feb. 1, 2025

Language: Английский

Citations

4
Maternal transfer of per- and polyfluoroalkyl substances (PFAS) in wild birds: A systematic review and meta-analysis DOI Creative Commons
Lorenzo Ricolfi, Matthew D. Taylor, Yefeng Yang

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 361, P. 142346 - 142346

Published: May 15, 2024

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer products. PFAS can accumulate animal tissues, resulting biomagnification adverse effects on wildlife, such as reproductive impairment. In bird species, transferred from mothers to eggs along with essential nutrients may affect embryo development. However, the extent of maternal transfer across different species compounds remains poorly understood. Here, we conducted a systematic review meta-analysis quantify wild birds investigate potential sources variation. We tested moderating compounds' physicochemical properties biological traits studied birds. The dataset included 505 measurements concentration 371 effect sizes derived 13 studies 16 25 compounds. Overall, all found 41% higher offspring than mothers. Specifically, contaminants were concentrated yolk, longer heavier showed preferential transfer, larger clutch size was associated decreased rate shown piscivorous opportunistic/diverse diets. A validation assessment good robustness overall meta-analytic result. Given crucial role maintaining ecological balance, this research article has relevant implications for modelling impacts ecosystems, human health.

Language: Английский

Citations

7
Structure and mechanism of nanoengineered membranes toward per- and polyfluoroalkyl substances (PFAS) removal from water: A critical review DOI
Md. Nahid Pervez, Tao Jiang, Yanna Liang

et al.

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 63, P. 105471 - 105471

Published: May 21, 2024

Language: Английский

Citations

4
Synthesis, purification and characterisation of novel PFAS following nontarget analysis DOI Creative Commons
Ana R. L. Araújo,

А. М. Павлов,

Jon Eigill Johansen

et al.

Journal of Fluorine Chemistry, Journal Year: 2025, Volume and Issue: 282, P. 110398 - 110398

Published: Jan. 25, 2025

Language: Английский

Citations

0
Association between plasma perfluoroalkyl substances and high-grade serous ovarian cancer overall survival: A nested case-control study DOI Creative Commons

Wei-Yi Xing,

Fang‐Hua Liu, Dongdong Wang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117825 - 117825

Published: Jan. 30, 2025

Language: Английский

Citations

0
Association Between Per- and Polyfluoroalkyl Substances and All-Cause Mortality in Diabetic Patients: Insights from a National Cohort Study and Toxicogenomic Analysis DOI Creative Commons
Zhengxiao Wei, Jinyu Chen,

Mei Xue

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(3), P. 168 - 168

Published: Feb. 27, 2025

Per- and polyfluoroalkyl substances (PFAS) are a group of environmental contaminants associated with various health risks; however, their relationship all-cause mortality in individuals diabetes remains unclear. A total 1256 participants from the National Health Nutrition Examination Survey (NHANES) were included to explore association between seven PFAS compounds diabetic patients. Preliminary logistic regression identified three (perfluorooctanoic acid [PFOA], perfluorooctane sulfonic [PFOS], 2-(N-methyl-PFOSA) acetate [MPAH]) as significantly population. The optimal cut-off values for PFOS, PFOA, MPAH determined using X-tile algorithm, categorized into high- low-exposure groups. Kaplan–Meier survival curves multivariable Cox proportional hazards models used assess levels risk. results showed that high PFOS increased risk patients (hazard ratio [HR]: 1.55, 95% confidence interval [CI]: 1.06–2.29), while PFOA no significant associations. To mechanisms underlying PFOS–mortality link, toxicogenomic analysis 95 overlapping genes exposure diabetes-related Comparative Toxicogenomics Database (CTD) GeneCards. Functional enrichment revealed key biological processes, such glucose homeostasis response peptide hormone, pathways including longevity regulating pathway, apoptosis, p53 signaling pathway. Protein–protein interaction network 10 hub genes, was found upregulate or downregulate mRNA expression, protein activity, notable effects on levels. These findings suggest contributes through related metabolism, cellular signaling. Our study provides new insights diabetes, highlighting need large-scale cohort studies further vivo vitro experiments validate these findings.

Language: Английский

Citations

0
Exposure to Per‐ and Polyfluoroalkyl Substances and the Risk of Prostate and Ovarian Cancer: An Epidemiologic Meta‐Analysis DOI Open Access
Shenglan Yang, Hui Dong, X. Gou

et al.

American Journal of Industrial Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants. Previous research has linked PFAS exposure to prostate ovarian cancer risk, however, the conclusions have been inconsistent. This purpose was determine relationship between at population level. We systematically reviewed three databases-PubMed, Web of Science, Embase-for from when these databases were established April 15, 2024. The quality retrieved evaluated using Newcastle-Ottawa Scale (NOS) measurement tool. Meta-analysis extracted data conducted Stata 18. also sensitivity subgroup analyses, as well Begg's Egger's tests. Twelve publications involved in analysis for cancer, six included ovary cancer. outcomes indicated that PFOS positively related (OR: 1.13, 95% CI: 1.00-1.28), while mixed 1.63, 1.49-1.78). source heterogeneity identified primarily attributable variations study design. No significant bias detected analysis. demonstrated an association both cancers. Further investigation is required clarify underlying mechanisms potential associations.

Language: Английский

Citations

0
Research Progress in Current and Emerging Issues of PFASs’ Global Impact: Long-Term Health Effects and Governance of Food Systems DOI Creative Commons
Jocelyn C. Lee, Slim Smaoui,

John Duffill

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(6), P. 958 - 958

Published: March 11, 2025

Per- and polyfluoroalkyl substances (PFASs) are found everywhere, including food, cosmetics, pharmaceuticals. This review introduces PFASs comprehensively, discussing their nature identifying interconnection with microplastics impacts on public health the environment. The human cost of decades delay, cover-ups, mismanagement plastic waste is outlined briefly explained. Following that, long-term effects critically assessed. Risk assessment then reviewed, mentioning different tools models. Scientific research in United States America analyzed, taking into consideration Center for Disease Control (CDC)'s PFAS Medical Studies Guidelines. impact activities studies around world have focused levels food products dietary intake countries such as China, European countries, USA Australia. Moreover, drinking water regard to risks, mitigation, regulatory needs, account chemical contaminants safety. Finally, briefings specific regions discussed, referring Australia, Vietnam, Canada, Europe, (USA), South America, Africa. crisis a multifaceted issue, exacerbated by mismanagement, it discussed context applying following problem-solving analytical tools: Domino Effect Model accident causation, Swiss Cheese Theory Model, Ishikawa Fish Bone Root Cause Analysis. Last but not least, PFASs' Sustainable Development Goals (SDGs) 2030 rigorously discussed.

Language: Английский

Citations

0
A research synthesis of humans, animals, and environmental compartments exposed to PFAS: A systematic evidence map and bibliometric analysis of secondary literature DOI Creative Commons
Lorenzo Ricolfi,

Catharina Vendl,

Jennifer Bräunig

et al.

Environment International, Journal Year: 2024, Volume and Issue: 190, P. 108860 - 108860

Published: June 30, 2024

Per- and polyfluoroalkyl substances (PFAS) are a class of widely used anthropogenic chemicals. Concerns regarding their persistence potential adverse effects have led to multiple secondary research publications. Here, we aim assess the resulting evidence base in systematic literature by examining gaps, evaluating quality reviews, exploring interdisciplinary connections.

Language: Английский

Citations

3
Clinical, histological, molecular, and toxicokinetic renal outcomes of per-/polyfluoroalkyl substances (PFAS) exposure: Systematic review and meta-analysis DOI
Jidapa Hanvoravongchai, Methasit Laochindawat, Yusuke Kimura

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 368, P. 143745 - 143745

Published: Nov. 1, 2024

Language: Английский

Citations

2