Association between remnant cholesterol (RC) and endometriosis: a cross-sectional study based on NHANES data

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 4, 2025

Prior research indicates a potential link between dyslipidemia and endometriosis (EMs). However, the relationship remnant cholesterol (RC) EMs has not been thoroughly investigated. Consequently, looking into clarifying connection RC was primary goal of this study. Following screening participants from NHANES dataset spanning 2001 to 2006, total 1,840 individuals were incorporated research. A weighted multivariable logistic regression analysis first performed investigate relation likelihood encountering EMs. To assess degree consistency in across different populations, additional subgroup analyses performed. In addition, researchers used extreme gradient boosting (XGBoost) technique area under receiver operating characteristic curve (ROC) evaluate how well recognized Lastly, both linear nonlinear relationships validated using generalized additive models (GAM), while dose-response connections investigated through restricted cubic spline models. After accounting for all confounders, strong correlation identified. particular, an increase one unit linked 135% rise developing Analyses subgroups revealed that these remained stable majority (interaction P-value > 0.05). Multivariable demonstrated RC's independent predictive value, maintaining statistical significance after adjusting confounders. The AUC 0.614 suggests moderate ability discriminate EMs, outperforming traditional markers like LDL-C sensitivity specificity. Furthermore, XGBoost identified as most critical predictor among lipid-related demographic variables. further GAM, which visually confirmed trend, RCS, provided evidence linearity. This study reveals clear having within US population, suggesting marker investigation understanding risk.

Language: Английский

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The association between vitamin E intake and remnant cholesterol, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol in US adults: a cross-sectional study

Lipids in Health and Disease, Journal Year: 2024, Volume and Issue: 23(1)

Published: Oct. 1, 2024

Language: Английский

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Association between residual cholesterol and sarcopenia in American adults

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 28, 2024

Remnant cholesterol (RC) is a novel lipid metabolism indicator; however, its relationship with sarcopenia has not been clearly established. This study was conducted to explore the association between RC and sarcopenia.

Language: Английский

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