Atherogenic index of plasma as a novel predictor for acute kidney injury and disease severity in acute pancreatitis: a retrospective cohort study DOI Creative Commons

Wen Wu,

Yiming Li, Yupei Zhang

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 25, 2025

The atherogenic index of plasma (AIP) can be used to reveal atherosclerosis. This study evaluated the AIP's efficacy in predicting prognosis acute kidney injury (AKI) and severity pancreatitis (AP). retrospective cohort recruited AP cases from First College Clinical Medical Science China Three Gorges University between January 2019 October 2023, including 1470 patients. AIP was computed using formula: log10 [serum triglyceride (mmol/L)/serum high-density lipoprotein cholesterol (mmol/L)]. relationships with AKI occurrence were validated multivariable logistic regression models, subgroup sensitivity analyses, curve fitting. Among patients AP, 250 (17%) developed 166 (11.3%) severe AP. positively correlated Potential confounders adjusted, consequently, linearly related (P for non-linearity: 0.731, OR 2.5, 95% CI 1.31–4.77,) 0.145, 3.1, 1.53–6.27), respectively. strength association AKI, along demonstrated through stratified analyses. Significant interactions not observed sex, age, hypertension, BMI, diabetes mellitus, SOFA score, BISAP etiology (all P interaction > 0.05). areas under curves incidence 0.64 0.65, is first suggest that critical assessment risk, recommending early screening among cases. Due observational nature study, potential residual confounding, need external validation larger, independent cohorts.

Language: Английский

Association of metabolic phenotypes with cardiovascular events in patients aged 18–45 with acute coronary syndrome DOI

Rongdi Xu,

Chen Wang,

Hongliang Cong

et al.

Endocrine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Language: Английский

Citations

0
Atherogenic index of plasma as a novel predictor for acute kidney injury and disease severity in acute pancreatitis: a retrospective cohort study DOI Creative Commons

Wen Wu,

Yiming Li, Yupei Zhang

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 25, 2025

The atherogenic index of plasma (AIP) can be used to reveal atherosclerosis. This study evaluated the AIP's efficacy in predicting prognosis acute kidney injury (AKI) and severity pancreatitis (AP). retrospective cohort recruited AP cases from First College Clinical Medical Science China Three Gorges University between January 2019 October 2023, including 1470 patients. AIP was computed using formula: log10 [serum triglyceride (mmol/L)/serum high-density lipoprotein cholesterol (mmol/L)]. relationships with AKI occurrence were validated multivariable logistic regression models, subgroup sensitivity analyses, curve fitting. Among patients AP, 250 (17%) developed 166 (11.3%) severe AP. positively correlated Potential confounders adjusted, consequently, linearly related (P for non-linearity: 0.731, OR 2.5, 95% CI 1.31–4.77,) 0.145, 3.1, 1.53–6.27), respectively. strength association AKI, along demonstrated through stratified analyses. Significant interactions not observed sex, age, hypertension, BMI, diabetes mellitus, SOFA score, BISAP etiology (all P interaction > 0.05). areas under curves incidence 0.64 0.65, is first suggest that critical assessment risk, recommending early screening among cases. Due observational nature study, potential residual confounding, need external validation larger, independent cohorts.

Language: Английский

Citations

0