ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 15, 2025
The
continuous
advances
in
micro-
and
nanofabrication
technologies
have
inevitably
led
to
major
improvements
field-effect
transistor
(FET)
design
architecture,
significantly
reducing
the
component
footprint
enabling
highly
efficient
integration
into
many
electronic
devices.
Combined
efforts
areas
of
materials
science,
life
sciences,
engineering
unlocked
opportunities
create
ultrasensitive
FET
chemo-
biosensor
devices
that
are
coupled
with
more
diverse
complex
requirements
terms
hardware
interfacing,
reproducible
functionality,
handling
analyte
samples.
Integration
biosensors
remains
one
bottlenecks
bridging
gap
between
fundamental
research
concepts
commercial
sensing
In
this
review,
we
critically
discuss
different
strategies
formats
context
key
requirements,
fabrication
scalability,
device
complexity.
intentions
review
1)
provide
a
practical
overview
successful
sensor
approaches,
2)
identify
crucial
challenges
factors
limiting
extent
integration,
3)
highlight
promising
perspectives
for
future
developments
integration.
We
believe
our
structured
insights
will
be
helpful
scientists
engineers
various
profiles
focusing
on
development
FET-based
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(44)
Published: May 22, 2024
Abstract
Recently,
field‐effect
transistors
(FETs)
have
emerged
as
a
novel
type
of
multiparameter,
high‐performance,
highly
integrated
platform
for
biochemical
detection,
leveraging
their
classical
three‐terminal
structure,
working
principles,
and
fabrication
methods.
Notably,
graphene
materials,
known
exceptional
electrical
optical
properties
well
biocompatibility,
serve
fundamental
component
these
devices,
further
enhancing
advantages
in
biological
detection.
This
review
places
special
emphasis
on
recent
advancements
transistor
(GFET)‐based
biosensors
focuses
four
main
areas:
i)
the
basic
concepts
FETs
specific
GFETs;
ii)
various
state‐of‐the‐art
approaches
to
enhance
performance
GFET‐based
terms
operating
principles
“3S”—stability,
sensitivity,
specificity;
iii)
multiplexed
detection
strategies
biosensors;
iv)
current
challenges
future
perspectives
field
biosensors.
It
is
hoped
that
this
article
can
profoundly
elucidate
development
GFET
inspire
broader
audience.
Biosensors,
Journal Year:
2024,
Volume and Issue:
14(11), P. 560 - 560
Published: Nov. 18, 2024
Wearable
biosensors
are
a
fast-evolving
topic
at
the
intersection
of
healthcare,
technology,
and
personalized
medicine.
These
sensors,
which
frequently
integrated
into
clothes
accessories
or
directly
applied
to
skin,
provide
continuous,
real-time
monitoring
physiological
biochemical
parameters
such
as
heart
rate,
glucose
levels,
hydration
status.
Recent
breakthroughs
in
downsizing,
materials
science,
wireless
communication
have
greatly
improved
functionality,
comfort,
accessibility
wearable
biosensors.
This
review
examines
present
status
biosensor
with
an
emphasis
on
advances
sensor
design,
fabrication
techniques,
data
analysis
algorithms.
We
analyze
diverse
applications
clinical
diagnostics,
chronic
illness
management,
fitness
tracking,
emphasizing
their
capacity
transform
health
facilitate
early
disease
diagnosis.
Additionally,
this
seeks
shed
light
future
healthcare
wellness
by
summarizing
existing
trends
new
advancements.
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 18, 2025
Abstract
Cortisol,
also
known
as
the
stress
hormone,
is
a
crucial
corticosteroid
hormone
that
significantly
increases
secretion
in
human
body
when
facing
notable
stress.
Monitoring
cortisol
levels
for
personal
management
and
diagnosis
treatment
of
certain
diseases.
Electrochemical
biosensors
combine
efficient
sensitivity
electrochemical
technology
with
high
specificity
biological
recognition
processes,
making
them
widely
applicable
analysis
fluid
components.
This
work
outlines
working
mechanism
biosensors,
focusing
particularly
on
sensing
elements
such
antibodies,
aptamers,
molecularly
imprinted
polymers.
It
provides
detailed
explanations
operational
principles
these
different
elements.
summarizes
evaluates
latest
advancements
detecting
fluids,
discussing
influence
sensor
design
performance.
Subsequently,
through
comparative
various
performances,
further
discusses
challenges
translating
laboratory
achievements
into
practical
applications,
including
enhancing
key
metrics
reusability,
reproducibility,
long‐term
stability,
continuous
monitoring
capability,
response
time.
Finally,
it
offers
insights
recommendations
achieving
real‐time,
continuous,
biosensors.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(27)
Published: Feb. 21, 2024
Metabolites
are
essential
molecules
involved
in
various
metabolic
processes,
and
their
deficiencies
excessive
concentrations
can
trigger
significant
physiological
consequences.
The
detection
of
multiple
metabolites
within
a
non-invasively
collected
biofluid
could
facilitate
early
prognosis
diagnosis
severe
diseases.
Here,
metal
oxide
heterojunction
transistor
(HJ-TFT)
sensor
is
developed
for
the
label-free,
rapid
uric
acid
(UA)
25(OH)Vitamin-D3
(Vit-D3)
human
saliva.
HJ-TFTs
utilize
solution-processed
In
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
6(9)
Published: Aug. 23, 2024
Abstract
The
potential
threat
posed
by
disease
outbreaks
to
diagnostic
instruments
demands
the
development
of
more
effective
biosensor
technologies
counteract
risks.
Diseases
like
SARS-CoV-2,
Ebola,
malaria,
cholera,
and
many
have
demonstrated
beyond
limits
health
care
that
new
advancements
are
required
for
early
detection
diagnosis.
rising
number
diseases
has
led
an
increasing
demand
biosensors
quicker
utilize
in
healthcare
settings.
A
incorporated
with
microfluidic
chips
offers
improved
compared
traditional
or
classical
biosensors.
Microfluidic
improve
performance
allowing
automation,
mixing,
separation,
throughput
processing,
transport
analytes
desired
reactors.
a
chip
sensitivity,
easy
operation
can
use
small
volumes
samples
process
results.
effectiveness
depends
also
on
materials
used
its
fabrication
there
which
reviewed
this
work.
This
paper
reviews
advantages
enhance
biosensors,
fabricate
chips,
electrodes
into
time
shortening
processing
at
point
service.
work
not
previously
addressed
other
including,
integration
cell-imprinted
polymers
sensors
delved
future
outlook.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(13), P. 6675 - 6693
Published: Jan. 1, 2024
Proteins
are
an
eminently
important
class
of
ubiquitous
biomacromolecules
with
diverse
biological
functions,
and
numerous
techniques
for
their
detection,
quantification,
localisation
have
been
developed.
Many
these
methods
exploit
the
selectivity
arising
from
molecular
recognition
proteins/antigens
by
immunoglobulins.
The
combination
surface-enhanced
Raman
scattering
(SERS)
such
"immuno"-techniques
to
immuno-SERS
(iSERS)
is
central
topic
this
review,
which
focused
on
colloidal
SERS
nanotags,
