ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 19, 2024
Stem
cell-based
therapies
are
emerging
as
significant
approaches
in
tissue
engineering
and
regenerative
medicine,
applicable
to
both
fundamental
scientific
research
clinical
practice.
Despite
remarkable
results
studies,
challenges
such
poor
standardization
of
graft
tissues,
limited
sources,
reduced
functionality
have
hindered
the
effectiveness
these
therapies.
In
this
review,
we
summarize
involved
fabricating
stem
cell
assisted
patches
substantial
strategies
for
designing
cell-laden
engineered
(SCP)
complement
existing
We
then
outline
potential
applications
SCP
advancing
regeneration
medicine.
By
combining
living
cells
with
patches,
can
enhance
functions
components,
particularly
applications.
Finally,
addressed
current
challenges,
ethical
considerations,
high
costs,
regulatory
hurdles
proposed
future
directions
overcome
barriers.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(17), P. e36707 - e36707
Published: Aug. 23, 2024
Diabetic
foot
ulcer
(DFU),
one
of
the
most
significant
complications
diabetes,
is
a
condition
that
causes
anatomical
and
functional
alterations
resulting
in
an
important
social
economic
impact,
related
to
disability
health
care
costs.
Recently,
three-dimensional
bioprinting
-
which
allows
fabrication
complex
biocompatible
structures
has
been
identified
as
promising
approach
field
regenerative
medicine
promote
healing
chronic
wounds,
such
DFU.
In
this
concise
review
we
highlight
relevant
recent
attempts
using
3D
bioprinted
constructs
MedComm – Biomaterials and Applications,
Journal Year:
2024,
Volume and Issue:
3(4)
Published: Nov. 10, 2024
Abstract
The
effective
treatment
of
skin
wounds
has
long
posed
a
significant
challenge
in
the
medical
field,
impacting
patient
comfort,
quality
life,
and
rate
outcome
wound
healing.
With
continuous
advancements
science
technology,
novel
materials
have
emerged,
providing
new
possibilities
for
treatment.
Among
these,
multifunctional
hydrogels
shown
considerable
potential
promoting
healing
as
type
dressing
material.
This
review
systematically
examines
progress
application
Initially,
structure
composition
are
introduced.
Subsequently,
classified,
wound‐healing
process
is
discussed
detail.
Traditional
modern
dressings
then
categorized,
with
particular
emphasis
on
characteristics
applications
hydrogel
dressings.
various
functions
healing,
including
antibacterial,
antioxidant,
hemostatic,
adhesive,
stimulus‐responsive,
status
monitoring,
reviewed.
paper
concludes
summary
existing
research
gaps
provides
insights
into
future
development
directions
hydrogels.
aims
to
guide
preparation
offer
theoretical
references
exploration
next‐generation
functional
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: May 28, 2024
Diabetes
is
a
metabolic
disorder
characterized
by
high
blood
sugar.
Uncontrolled
glucose
affects
the
circulatory
system
in
an
organism
intervening
circulation.
The
can
lead
to
macrovascular
(large
vessels)
and
microvascular
(small
complications.
Due
this,
vital
organs
(notably
brain,
eyes,
feet,
heart,
kidneys,
lungs
nerves)
get
worsen
diabetic
patients
if
not
treated
at
earliest.
Therefore,
acquiring
treatment
appropriate
time
very
important
for
managing
diabetes
other
complications
that
are
caused
due
diabetes.
root
cause
occurrence
of
various
health
uncontrolled
levels.
This
review
presents
consolidated
account
applications
types
three-dimensional
(3D)
printing
bioprinting
technologies
treating
as
well
impaired
Herein,
development
biosensors
(for
diagnosis),
oral
drug
formulations,
transdermal
carriers,
orthotic
insoles
scaffolds
treatment)
discussed.
Next
fabrication
3D
bioprinted
cell-seeded
hydrogels
(pancreas
engineering
producing
insulin
bone
defects)
explained.
As
final
application,
disease
models
high-throughput
screening
ant-diabetic
drugs
Lastly,
challenges
future
perspective
associated
with
use
against
its
related
chronic
have
been
put
forward.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 19, 2024
Stem
cell-based
therapies
are
emerging
as
significant
approaches
in
tissue
engineering
and
regenerative
medicine,
applicable
to
both
fundamental
scientific
research
clinical
practice.
Despite
remarkable
results
studies,
challenges
such
poor
standardization
of
graft
tissues,
limited
sources,
reduced
functionality
have
hindered
the
effectiveness
these
therapies.
In
this
review,
we
summarize
involved
fabricating
stem
cell
assisted
patches
substantial
strategies
for
designing
cell-laden
engineered
(SCP)
complement
existing
We
then
outline
potential
applications
SCP
advancing
regeneration
medicine.
By
combining
living
cells
with
patches,
can
enhance
functions
components,
particularly
applications.
Finally,
addressed
current
challenges,
ethical
considerations,
high
costs,
regulatory
hurdles
proposed
future
directions
overcome
barriers.
