The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: April 25, 2024

Abstract Several studies suggest that oral pathogenic biofilms cause persistent infections. Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even result in tooth loss. Furthermore, the accumulation of germs around dental implant may lead to peri-implantitis, which damages surrounding bone and gum tissue. bacterial biofilm contamination causes soft tissue irritation adjacent resorption, severely compromising health. On decontaminated surfaces, however, re-osseointegration cannot be induced standard removal techniques such as mechanical cleaning antiseptic treatment. A family nanoparticles known nanozymes (NZs) comprise highly catalytically active multivalent metal components. The most often employed NZs with antibacterial activity are those have peroxidase (POD) activity, among other types NZs. Since less expensive, more easily produced, stable than natural enzymes, they hold great promise for use various applications, including treating microbial significantly contributed studying success rates periodontal health maintenance periodontics implantology. An extensive analysis research their applications managing conditions, caries, pulp disorders, ulcers, infections mouth. To combat bacteria, this review concentrates imitate enzymes implantology periodontology. With view future, there several ways might used treat disorders antibacterially. Graphical

Language: Английский

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Recent advances in nanomaterial-based biosensor for periodontitis detection

Journal of Biological Engineering, Journal Year: 2024, Volume and Issue: 18(1)

Published: April 18, 2024

Periodontitis, a chronic inflammatory condition caused by bacteria, often causes gradual destruction of the components that support teeth, such as alveolar bone, cementum, periodontal ligament, and gingiva. This ultimately results in teeth becoming loose eventually falling out. Timely identification has crucial role preventing controlling its progression. Clinical measures are used to diagnose periodontitis. However, now, there is hunt for alternative diagnostic monitoring methods due progress technology. Various biomarkers have been assessed using multiple bodily fluids sample sources. Furthermore, conventional categorization factors do not provide significant insights into present disease activity, severity amount tissue damage, future development, responsiveness treatment. In recent times, growing utilization nanoparticle (NP)-based detection strategies create quick efficient assays. Every single one these platforms leverages distinct characteristics NPs identify Plasmonic include metal NPs, quantum dots (QDs), carbon base nanozymes, exceptionally potent light absorbers scatterers. These find application labeling, surface-enhanced spectroscopy, color-changing sensors. Fluorescent function photostable sensitive instruments capable labeling various biological targets. article presents comprehensive summary latest developments effective detect

Language: Английский

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Mesenchymal Stem Cell-based Scaffolds in Regenerative Medicine of Dental Diseases

Stem Cell Reviews and Reports, Journal Year: 2024, Volume and Issue: 20(3), P. 688 - 721

Published: Feb. 3, 2024

Language: Английский

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Fabrication of temperature and pH dual-sensitive semi-interpenetrating network hydrogel with enhanced adhesion and antibacterial properties

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128343 - 128343

Published: April 1, 2025

Language: Английский

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Enhanced photocatalytic degradation of diazinon using Ni:ZnO/Fe3O4 nanocomposite under solar light

Journal of the Taiwan Institute of Chemical Engineers, Journal Year: 2024, Volume and Issue: 161, P. 105528 - 105528

Published: May 14, 2024

Language: Английский

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Green synthesis of crystalline silver nanoparticle by bio-mediated plant extract: A critical perspective analysis

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 39, P. 101272 - 101272

Published: July 27, 2024

Language: Английский

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Harnessing the Potential of Sargassum Latifolium for Sustainable Synthesis of Ag/Bi2O3-Curdlan Nanocomposites: Phytochemical Characterization and Biological Applications

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

Language: Английский

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Recent advances in nanomaterials and their mechanisms for infected wounds management

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101553 - 101553

Published: Feb. 5, 2025

Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with increasing prevalence antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due limited penetration, resistance development, and inadequate local concentration at wound sites. These limitations necessitate exploration alternative strategies that can overcome drawbacks conventional therapies. Nanomaterials have emerged as promising solution for tackling bacterial infections facilitating healing, thanks their distinct physicochemical characteristics multifunctional capabilities. This review highlights latest developments nanomaterials demonstrated enhanced antibacterial efficacy improved healing outcomes. The mechanisms are varied, including ion release, chemodynamic therapy, photothermal/photodynamic electrostatic interactions, delivery drugs, which not only combat but also address challenges posed biofilms antibiotic resistance. Furthermore, these create an optimal environment tissue regeneration, promoting faster closure. By leveraging unique attributes nanomaterials, there is significant opportunity revolutionize management wounds markedly improve patient

Language: Английский

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Biogenic Nickel Oxide Nanoparticles: Synthesis, Characterization and Biomedical Potential

Molecular Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

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The current advancements in chitosan nanoparticles in the management of non-surgical periodontitis treatment

Nanotoxicology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 35

Published: March 28, 2025

Because of the intricate interactions between bacteria internalization in periodontal cells and chronic inflammatory activation, disorders remain difficult. Furthermore, primary cause adult tooth loss is periodontitis, one most common dental worldwide. The key to preventing periodontitis has been reduce development generation substances that eventually erode tissue surrounding supporting teeth. there are several disadvantages treating with antibiotics administered systemically. A naturally occurring polymer antibacterial anti-inflammatory properties chitosan (CS). CS highly interested disease as a medicine carrier due its actions against anaerobic microorganisms possible properties. Due multifactorial pathophysiology combining antimicrobial medications single drug delivery method preferable administering them separately since it increases therapeutic range when numerous organisms present. As result, CS-based technologies, such gels, micro, nanoparticles (NPs), were created transport drugs pocket over an extended period. This research provides overview existing benefits CSNP on periodontitis. information might be used create substitutes based for infections.

Language: Английский

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