Hydrogel-Based Scaffolds: Advancing Bone Regeneration Through Tissue Engineering

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 175 - 175

Published: Feb. 27, 2025

Bone tissue engineering has emerged as a promising approach to addressing the limitations of traditional bone grafts for repairing defects. This regenerative medicine strategy leverages biomaterials, growth factors, and cells create favorable environment regeneration, mimicking body’s natural healing process. Among various biomaterials explored, hydrogels (HGs), class three-dimensional, hydrophilic polymer networks, have gained significant attention scaffolds engineering. Thus, this review aimed investigate potential synthetic HGs, molecules used its functionalization, enhanced applications. HGs offer several advantages such scaffolds, including biocompatibility, biodegradability, tunable mechanical properties, ability encapsulate deliver bioactive molecules. These properties make them ideal candidates supporting cell attachment, proliferation, differentiation, ultimately guiding formation new tissue. The design optimization HG-based involve adapting their composition, structure, meet specific requirements regeneration. Current research focuses on incorporating molecules, factors cytokines, into HG further enhance osteoinductive osteoconductive properties. Additionally, strategies improve strength degradation kinetics are being explored ensure long-term stability support formation. development advanced holds great revolutionizing providing effective treatment options patients with

Language: Английский

Embracing the future: The application of regenerative biomaterials in the spinal disorders

Biomedical Technology, Journal Year: 2024, Volume and Issue: 9, P. 100068 - 100068

Published: Dec. 25, 2024

Language: Английский