Nanobiotechnology Unveils the Power of Probiotics: A Comprehensive Review on the Synergistic Role of Probiotics and Advanced Nanotechnology in Enhancing Geriatric Health. DOI Open Access

Onkar Kadam,

Swayamprava Dalai, Brijesh Singh Chauhan

et al.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

The geriatric population, comprising ages 65 and above, encounters distinct health obstacles because of physiological changes heightened vulnerability to diseases. New technologies are being investigated tackle the intricate requirements this population. Recent advancements in probiotics nanotechnology offer promising strategies enhance by improving nutrient absorption, modulating gut microbiota, delivering targeted therapeutic agents. Probiotics play a crucial role maintaining homeostasis, reducing inflammation, supporting metabolic functions. However, challenges such as limited viability efficacy harsh gastrointestinal conditions hinder their potential. Advanced can overcome these constraints enhancing through nano-encapsulation, controlled delivery, improvement bioavailability. This review explores synergistic potential advanced addressing age-related concerns. It highlights key developments probiotic formulations, nano-based delivery systems, combined impact on health, immunity, neuroprotection. convergence represents novel transformative approach promoting healthy aging, paving way for innovative interventions.

Language: Английский

The Utilization of Biopolymer Hydrogels to Encapsulate and Protect Probiotics in Foods DOI
Great Iruoghene Edo, Alice Njolke Mafe, Patrick Othuke Akpoghelie

et al.

Process Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

2

Modified-Release Pulmonary Delivery Systems for Labile Bioactives: Design, Development, and Applications DOI Creative Commons

Shivani Nana,

Mershen Govender, Yahya E. Choonara

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 470 - 470

Published: April 3, 2025

Pulmonary delivery of bioactives has shown to be a promising route for the treatment respiratory conditions, however, numerous physiological barriers, such as mucociliary clearance and immune responses, pose significant hurdles efficacy. These barriers specifically affect labile mRNA, peptides, proteins, probiotics, which are susceptible degradation due prevailing conditions. Various drug platforms have been developed address these challenges, including, among others, polymeric nanoparticles, micelles, liposomes, solid lipid nanoparticles that encapsulate protect during formulation administration, enabling improved bioavailability, sustained release, enhanced stability, while further modification allows targeted delivery. This review explores advanced systems designed release active agents in controlled manner lung, with specific focus provided on effective pulmonary considerations overcome challenges. The outlook this pertinent field study additionally provided, highlighting potential bioactive prevention variety ailments.

Language: Английский

Citations

1

Nanobiotechnology Unveils the Power of Probiotics: A Comprehensive Review on the Synergistic Role of Probiotics and Advanced Nanotechnology in Enhancing Geriatric Health. DOI Open Access

Onkar Kadam,

Swayamprava Dalai, Brijesh Singh Chauhan

et al.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

The geriatric population, comprising ages 65 and above, encounters distinct health obstacles because of physiological changes heightened vulnerability to diseases. New technologies are being investigated tackle the intricate requirements this population. Recent advancements in probiotics nanotechnology offer promising strategies enhance by improving nutrient absorption, modulating gut microbiota, delivering targeted therapeutic agents. Probiotics play a crucial role maintaining homeostasis, reducing inflammation, supporting metabolic functions. However, challenges such as limited viability efficacy harsh gastrointestinal conditions hinder their potential. Advanced can overcome these constraints enhancing through nano-encapsulation, controlled delivery, improvement bioavailability. This review explores synergistic potential advanced addressing age-related concerns. It highlights key developments probiotic formulations, nano-based delivery systems, combined impact on health, immunity, neuroprotection. convergence represents novel transformative approach promoting healthy aging, paving way for innovative interventions.

Language: Английский

Citations

0