Cited by Higenamine inhibits acute and chronic inflammatory pain through modulation of TRPV4 channels

A bibliometric analysis of the Fasting-Mimicking Diet DOI

Xiaoxiao Lin, Yue Gao

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 23, 2024

The Fasting-Mimicking Diet (FMD) is a nutritional strategy that involves significantly reducing calorie intake for specific period to mimic the physiological effects of fasting while still providing body with nutrition. Our study aimed conduct bibliometric explore latest publishing trends and areas intense activity within sphere FMD. We extracted data on FMD publications from Web Science Core Collection (WOSCC) database. analysis was conducted by WOSCC Online Analysis Platform VOSviewer 1.6.16. In total, there were 169 945 authors 342 organizations 25 countries/regions, published in 111 journals. most productive country, organization, author, journal United States, University Southern California, Valter D. Longo, Nutrients, respectively. first high-cited document Ageing Research Reviews authored Mattson et al. this study, they discuss various health benefits including improved metabolic health, weight management, even potential delaying aging processes risk chronic diseases. conclusion, our main research hotspots frontiers cancer, metabolic-related diseases, cognitive improvement. may have some multiple diseases which should be further investigated.

Language: Английский

Citations

Inhibition of 5-hydroxyindoleacetic acid to reduce neutrophil extracellular trap production improves lung condition in chronic obstructive pulmonary disease mice DOI

Qiang Zeng,

Lei Xue,

Wu Li

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: March 11, 2025

Background Neutrophil extracellular trap (NET) correlate with chronic obstructive pulmonary disease (COPD) severity. Platelets can promote NET generation. However, serotonin alone or serotonin-deficient platelets do not adequately production. The metabolism of to 5-hydroxyindoleacetic acid (5-HIAA) in may be the key this difference.

Language: Английский

Citations

Neutrophil extracellular traps induced by neoadjuvant chemotherapy of breast cancer promotes vascular endothelial damage DOI

Linghui Kong,

Song Hu, Ying Zhao

et al.

Breast Cancer Research, Journal Year: 2025, Volume and Issue: 27(1)

Published: April 23, 2025

The mechanisms underpinning neoadjuvant chemotherapy-induced vascular endothelial injury in breast cancer remain elusive. Our study aims to demonstrate that Neutrophil Extracellular Traps (NETs) play a pivotal role cancer, elucidating upregulation of Solute Carrier 11a1 (Slc11a1) modulates Reactive Oxygen Species (ROS) generation, which may be critical for NETs formation. We investigated the impact chemotherapy on formation and by analyzing dsDNA serum markers patients, cells, mouse models. RNA sequencing neutrophils from models was performed identify potential formation-associated gene Slc11a1, further validated through cellular animal experiments assessing Slc11a1 expression, intracellular ferrous ion content, ROS levels. Knockdown human were also confirm phenotypic results. revealed plasma significantly elevated patients undergoing docetaxel & carboplatin (TCb) chemotherapy, compared controls. In these associated with augmentation markers. Chemotherapy demonstrated TCb treatment markedly injury, can mitigated CI-amidine, protein-arginine deiminase inhibitor. neutrophils, we chemotherapeutic agents (combination carboplatin) induced NETs, subsequently facilitated damage umbilical vein cells vitro. identified as key formation-related gene, upregulated leading increased content generation. its reversal effect TCb-induced upregulation, research underscores capacity augment Slc11a1-mediated is linked injury. elucidates underlying perioperative offering novel insights into therapeutic management strategies patients.

Language: Английский

Citations

Astrocyte-derived lipocalin 2 promotes inflammation and scarring after spinal cord injury by activating SMAD in mice DOI

Xuankang Wang,

Zhijie Zhu,

Zhihao Zhang

et al.

Experimental Neurology, Journal Year: 2024, Volume and Issue: 380, P. 114915 - 114915

Published: Aug. 8, 2024

Language: Английский

Citations

The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy DOI

Donato Inverso, Carlotta Tacconi, Serena Ranucci

et al.

European Journal of Immunology, Journal Year: 2024, Volume and Issue: 54(12)

Published: Sept. 12, 2024

G protein-coupled receptors (GPCRs) are vital cell surface that govern a myriad of physiological functions. Despite their crucial role in regulating antitumor immunity and tumorigenesis, therapeutic applications targeting GPCRs oncology currently limited. This review offers focused examination selected protumorigenic chemokine metabolite-sensing GPCRs. Specifically, the highlights five able to orchestrate tumor immunobiology at three main levels: immunity, cancer expansion, blood vessel development. The culminates by illuminating emerging therapies discussing innovative strategies harness full potential GPCR-targeted treatments, applying multireceptor patient-specific logic.

Language: Английский

Citations

Shaoyao Gancao Decoction Alleviates Paclitaxel-Induced Cognitive Impairment by Activating PTEN/PI3K/AKT Pathway to Inhibit NETs Formation DOI

Ying Xu, Su Yue, Yuwen Hu

et al.

Phytomedicine Plus, Journal Year: 2024, Volume and Issue: unknown, P. 100649 - 100649

Published: Oct. 1, 2024

Language: Английский

Citations

Higenamine inhibits acute and chronic inflammatory pain through modulation of TRPV4 channels DOI

Ying Ju, Changming Wang,

Juanjuan Yu

et al.

European Journal of Pharmacology, Journal Year: 2023, Volume and Issue: 964, P. 176295 - 176295

Published: Dec. 26, 2023

Language: Английский

Citations