Bi-Anodal Transcranial Direct Current Stimulation Combined With Treadmill Walking Decreases Motor Cortical Activity in Young and Older Adults DOI
Diego Orcioli‐Silva,

Aisha Islam,

Mark R. Baker

et al.

Frontiers in Aging Neuroscience, Journal Year: 2021, Volume and Issue: 13

Published: Dec. 3, 2021

Background: Walking in the “real world” involves motor and cognitive processes. In relation to this, declines both function cognition contribute age-related gait dysfunction. Transcranial direct current stimulation (tDCS) treadmill walking (STW) have potential improve gait, particularly during dual-task (DTW); whilst performing a task. Our aims were analyze effects of combined anodal tDCS + STW intervention on cortical activity DTW. Methods: Twenty-three young adults (YA) 21 older (OA) randomly allocated active or sham groups. Participants performed 5-min mixed (alternating 30 s bouts DTW) before after 20-min STW. Anodal electrodes placed over left prefrontal cortex (PFC) vertex (Cz) using 9 cm 2 at 0.6 mA. Cortical PFC, primary (M1), premotor (PMC), supplementary area (SMA) bilaterally recorded functional near-infrared spectroscopy (fNIRS) system. Oxygenated hemoglobin (HbO ) levels analyzed as indicators activity. An accelerometer measured parameters. We calculated difference between DTW for HbO applied linear models which included age group (YA vs. OA), condition (sham active), time (pre- post-intervention) fixed effects. Treadmill belt speed was covariate. Partial correlation tests also performed. Results: A main effect observed. OA displayed higher PFC M1, unilaterally right PMC variability than YA. M1 decreased YA following There no overall However, negative correlations observed changes stride length intervention. Conclusion: Increased multiple areas may act compensatory mechanism. Reduction with suggests improved neural efficiency.

Language: Английский

Effects of Transcranial Direct Current Stimulation Combined With Physical Training on the Excitability of the Motor Cortex, Physical Performance, and Motor Learning: A Systematic Review DOI Creative Commons
Baofeng Wang, Songlin Xiao,

Changxiao Yu

et al.

Frontiers in Neuroscience, Journal Year: 2021, Volume and Issue: 15

Published: April 9, 2021

Purpose: This systematic review aims to examine the efficacy of transcranial direct current stimulation (tDCS) combined with physical training on excitability motor cortex, performance, and learning. Methods: A search was performed PubMed, Web Science, EBSCO databases for relevant research published from inception August 2020. Eligible studies included those that used a randomized controlled design reported effects tDCS improve motor-evoked potential (MEP), dynamic posture stability index (DPSI), reaction time, error rate participants without nervous system diseases. The risk bias assessed by Cochrane assessment tool. Results: Twenty-four an initial yield 768 met eligibility criteria. considered low. Results showed anodal can significantly increase MEP amplitude, decrease DPSI, muscle strength, time in learning tasks. Moreover, gain effect is greater than sham training. Conclusion: effectively results encourage further understand synergistic

Language: Английский

Citations

47
Transcranial Direct Current Stimulation for Parkinson's Disease: A Systematic Review and Meta-Analysis DOI Creative Commons
Xiang Liu, Huiyu Liu, Zicai Liu

et al.

Frontiers in Aging Neuroscience, Journal Year: 2021, Volume and Issue: 13

Published: Oct. 28, 2021

Background: Parkinson's disease is a common neurodegenerative disorder with motor and non-motor symptoms. Recently, as adjuvant therapy, transcranial direct current stimulation (tDCS) has been shown to improve the function of patients (PD). This systematic review aimed evaluate existing evidence for efficacy tDCS PD. We included English databases (PubMed, Cochrane Library, Embase, Web Science) Chinese [Wanfang database, China National Knowledge Infrastructure (CNKI), Science Technology Journal Database (VIP), Biology Medicine (CBM)] without restricting year publication. Twenty-one studies, total 736 participants, were in analysis. Two independent researchers extracted data characteristics each study. There was significant pooled effect size (−1.29; 95% CI = −1.60, −0.98; p < 0.00001; I 2 0%) Unified PD Rating Scale (UPDRS) Montreal cognitive assessment (SMD 0.87, 0.50 1.24; 0%). The poor observed UPDRS III scores −0.13; −0.64, 0.38; 0.61; 77%), similar results timed up go (TUG) test, Berg balance scale, gait assessment. this meta-analysis showed that there insufficient improves However, seemed their performance. Further multicenter research larger sample needed. In addition, future should focus on determining parameters are most beneficial functional recovery

Language: Английский

Citations

42
Transcranial Direct Current Stimulation (tDCS) as a Useful Rehabilitation Strategy to Improve Cognition in Patients With Alzheimer's Disease and Parkinson's Disease: An Updated Systematic Review of Randomized Controlled Trials DOI Creative Commons
Davide Maria Cammisuli,

F. Cignoni,

Roberto Ceravolo

et al.

Frontiers in Neurology, Journal Year: 2022, Volume and Issue: 12

Published: Feb. 2, 2022

Alzheimer's disease (AD) and Parkinson's (PD) are neurodegenerative disorders characterized by cognitive impairment functional decline increasing with progression. Within non-pharmacological interventions, transcranial direct current stimulation (tDCS) might represent a cost-effective rehabilitation strategy to implement abilities positive implications for autonomy quality-of-life of patients. Our systematic review aimed at evaluating the effects tDCS upon cognition in people suffering from AD PD. We searched randomized controlled trials (RCTs) into PubMed, Web Science, Cochrane Library. Three authors extracted data interest, neuropsychological tests or experimental tasks scores as outcome measures. A total 17 RCTs (10 7 PD) were included. Compared sham stimulation, may improve global recognition memory patients also some executive functions (i.e., divided attention, verbal fluency, reduction sensitivity interference) Criticism remains about benefits other investigated domains. Despite preliminary emerging evidences, larger common measures long-term follow-ups establishing longevity observed necessary future research applied psychology field, alongside improved clinical guidelines on pertaining electrodes montage, sessions number, duration intensity battery be used.

Language: Английский

Citations

32
Aerobic Exercise Combined With Transcranial Direct Current Stimulation Over the Prefrontal Cortex in Parkinson Disease: Effects on Cortical Activity, Gait, and Cognition DOI
Núbia Ribeiro da Conceição, Lílian Teresa Bucken Gobbi, Priscila Nóbrega‐Sousa

et al.

Neurorehabilitation and neural repair, Journal Year: 2021, Volume and Issue: 35(8), P. 717 - 728

Published: May 28, 2021

Background Since people with Parkinson disease (PD) rely on limited prefrontal executive resources for the control of gait, interventions targeting cortex (PFC) may help in managing PD-related gait impairments. Transcranial direct current stimulation (tDCS) can be used to modulate PFC excitability and improve cognitive functions gait. Objective We investigated effects adding anodal tDCS applied over a session aerobic exercise cognition, activity while walking PD. Methods A total 20 PD participated this randomized, double-blinded, sham-controlled crossover study. Participants attended two 30-minute sessions (cycling at moderate intensity) combined different conditions (active- or sham-tDCS), 1 week apart. The order was counterbalanced across sample. Anodal (2 mA minutes [active-tDCS] 10 s [sham-tDCS]) targeted most affected hemisphere. Spatiotemporal parameters, functions, were assessed before immediately after each session. Results Compared pre-assessment, participants decreased step time variability (effect size: −0.4), shortened simple choice reaction times sizes: −0.73 −0.57, respectively), increased stimulated hemisphere 0.54) only + active-tDCS. Conclusion addition led immediate positive variability, processing speed,

Language: Английский

Citations

41
The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease: a systematic review DOI Creative Commons
Fateme Pol, Mohammad Ali Salehinejad, Hamzeh Baharlouei

et al.

Translational Neurodegeneration, Journal Year: 2021, Volume and Issue: 10(1)

Published: June 29, 2021

Abstract Background Gait problems are an important symptom in Parkinson’s disease (PD), a progressive neurodegenerative disease. Transcranial direct current stimulation (tDCS) is neuromodulatory intervention that can modulate cortical excitability of the gait-related regions. Despite increasing number tDCS studies PD, efficacy this technique for improving gait has not been systematically investigated yet. Here, we aimed to explore effects on based available experimental studies. Methods Using PRISMA (Preferred Reporting Items Systematic Reviews and Meta-Analyses) approach, PubMed, Web Science, Scopus, PEDro databases were searched randomized clinical trials assessing effect patients with PD. Results Eighteen included systematic review. Overall, targeting motor cortex supplementary area bilaterally seems be promising rehabilitation Studies dorosolateral prefrontal or cerebellum showed more heterogeneous results. More needed compare different protocols, including protocols applying alone and/or combination conventional treatment Conclusions approach Anodal over areas shown positive gait, but other less promising. However, heterogeneities methods results have made it difficult draw firm conclusions. Therefore, explorations required optimize efficacy.

Language: Английский

Citations

40
Reaching and Grasping Movements in Parkinson’s Disease: A Review DOI Creative Commons
Alessio Fasano, Alberto Mazzoni, Egidio Falotico

et al.

Journal of Parkinson s Disease, Journal Year: 2022, Volume and Issue: 12(4), P. 1083 - 1113

Published: March 4, 2022

Parkinson’s disease (PD) is known to affect the brain motor circuits involving basal ganglia (BG) and induce, among other signs, general slowness paucity of movements. In upper limb movements, PD patients show a systematic prolongation movement duration while maintaining sufficient level endpoint accuracy. appears cause impairments not only in execution, but also initiation planning, as revealed by abnormal preparatory activity motor-related areas. Grasping affected well, particularly coordination hand aperture with transport phase. last fifty years, numerous behavioral studies attempted clarify mechanisms underlying these anomalies, speculating on plausible role that BG-thalamo-cortical circuitry may play normal pathological control. Still, many questions remain open, especially concerning management speed-accuracy tradeoff online feedback this review, we summarize literature results reaching grasping parkinsonian patients. We analyze relevant hypotheses origins dysfunction, focusing control aspects involved different phases corresponding played BG. conclude an insight into innovative stimulation techniques computational models recently proposed, which might be helpful further clarifying through affects

Language: Английский

Citations

27
Transcranial direct current stimulation for balance rehabilitation in neurological disorders: A systematic review and meta-analysis DOI
Victor Spiandor Beretta, Paulo Cezar Rocha dos Santos, Diego Orcioli‐Silva

et al.

Ageing Research Reviews, Journal Year: 2022, Volume and Issue: 81, P. 101736 - 101736

Published: Sept. 16, 2022

Language: Английский

Citations

25
Non-Pharmacological Interventions for Depression and Anxiety in Parkinson’s Disease DOI
Erwin E. H. van Wegen, Tim D. van Balkom, Mark A. Hirsch

et al.

Journal of Parkinson s Disease, Journal Year: 2024, Volume and Issue: 14(s1), P. S135 - S146

Published: April 9, 2024

Non-pharmacological interventions, including cognitive-behavioral therapy (CBT), non-invasive brain stimulation (NIBS), electroconvulsive (ECT), light (LT), and physical rehabilitation/exercise, have shown promise as effective approaches to treat symptoms of depression anxiety in individuals with Parkinson's disease (PD). In this narrative literature overview, we discuss the state-of-the-art regarding these treatment options address future perspectives for clinical practice research. interventions hold PD. There is meta-analytic evidence efficacy CBT, NIBS, ECT, LT, exercise on improving depressive symptoms. For symptoms, CBT shows large effects but scientific other non-pharmacological limited. Importantly, treatments are safe no or mild side-effects. More research needed tailor individuals' needs combined may provide synergistic effects.We conclude that should be considered alternative augmentative pharmacological neurosurgical

Language: Английский

Citations

5
Physiotherapy management of Parkinson's disease DOI Creative Commons
Marco Y.C. Pang

Journal of physiotherapy, Journal Year: 2021, Volume and Issue: 67(3), P. 163 - 176

Published: June 19, 2021

Language: Английский

Citations

31
Biomechanics of balance DOI
Victor Spiandor Beretta, Paulo Cezar Rocha dos Santos, Diego Orcioli‐Silva

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 155 - 170

Published: Jan. 1, 2025

Language: Английский

Citations

0