Prolonged Diagnostic Interval Leads to High Lymphoma Related Mortality in a Prospective Cohort of People with HIV Undergoing Fine Needle Aspiration DOI Open Access
Samantha L. Vogt, Khuthadzo Hlongwane,

Arshia Arora

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(6), P. 1005 - 1005

Published: March 17, 2025

Background: HIV is associated with an increased risk of aggressive lymphomas. Lymphadenopathy common at the time presentation; therefore, we set out to understand lymphoma diagnosis in people (PWH) undergoing fine needle aspiration (FNA). Methods: A prospective, observational cohort PWH, age ≥ 18 years, FNA Soweto, South Africa was established between September 2021 and December 2022. Participants were followed up for 8 months provided consent a medical record review. Results: One hundred forty-six participants enrolled, including 76 females (52%) median 40 years CD4 count 216 cells/μL. TB most (n = 62; 42%), by 21; 14%), whom 10 (48%) died either prior or initiating chemotherapy. An additional 2 (10%) still awaiting biopsy confirmation months. participant’s suggestive both TB. The healthcare provider interval, from presentation diagnosis, 85 days. Conclusions: While among PWH FNA, leading cause death. As deaths occurred chemotherapy, interventions expedite this high-risk population are needed.

Language: Английский

Prolonged Diagnostic Interval Leads to High Lymphoma Related Mortality in a Prospective Cohort of People with HIV Undergoing Fine Needle Aspiration DOI Open Access
Samantha L. Vogt, Khuthadzo Hlongwane,

Arshia Arora

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(6), P. 1005 - 1005

Published: March 17, 2025

Background: HIV is associated with an increased risk of aggressive lymphomas. Lymphadenopathy common at the time presentation; therefore, we set out to understand lymphoma diagnosis in people (PWH) undergoing fine needle aspiration (FNA). Methods: A prospective, observational cohort PWH, age ≥ 18 years, FNA Soweto, South Africa was established between September 2021 and December 2022. Participants were followed up for 8 months provided consent a medical record review. Results: One hundred forty-six participants enrolled, including 76 females (52%) median 40 years CD4 count 216 cells/μL. TB most (n = 62; 42%), by 21; 14%), whom 10 (48%) died either prior or initiating chemotherapy. An additional 2 (10%) still awaiting biopsy confirmation months. participant’s suggestive both TB. The healthcare provider interval, from presentation diagnosis, 85 days. Conclusions: While among PWH FNA, leading cause death. As deaths occurred chemotherapy, interventions expedite this high-risk population are needed.

Language: Английский

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