Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1493 - 1493
Published: Dec. 6, 2024
Extracellular
vesicles
(EVs)
are
small,
membrane-bound
particles
secreted
by
cells
into
the
extracellular
environment,
playing
an
increasingly
recognized
role
in
inter-organ
communication
and
regulation
of
various
physiological
processes.
Regarding
redox
homeostasis
context,
EVs
play
a
pivotal
propagating
mitigating
oxidative
stress
signals
across
different
organs.
Cells
under
release
containing
signaling
molecules
that
can
influence
status
distant
tissues.
starting
to
be
as
contributors
brain-liver
communication.
Therefore,
this
review,
we
show
how
imbalance
affect
brain
liver.
We
propose
mediators
axis.
Molecular Medicine Reports,
Journal Year:
2024,
Volume and Issue:
30(5)
Published: Sept. 6, 2024
The
tetraspanin
family
of
membrane
proteins
is
essential
for
controlling
different
biological
processes
such
as
cell
migration,
penetration,
adhesion,
growth,
apoptosis,
angiogenesis
and
metastasis.
present
review
summarized
the
current
knowledge
regarding
expression
roles
tetraspanins
in
types
cancer
digestive
system,
including
gastric,
liver,
colorectal,
pancreatic,
esophageal
oral
cancer.
Depending
on
type
context
cancer,
can
act
either
tumor
promoters
or
suppressors.
In
review,
importance
serving
biomarkers
targets
system‑related
was
emphasized.
Additionally,
molecular
mechanisms
underlying
involvement
progression
metastasis
were
explored.
Furthermore,
challenges
are
addressed
future
research
directions
advancing
investigations
related
to
system
malignancies
proposed.
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2665 - 2665
Published: Nov. 22, 2024
Liver
fibrosis
represents
a
common
pathway
in
the
progression
of
various
chronic
liver
diseases
towards
cirrhosis
and
failure.
Extracellular
vesicles
(EVs)
are
membrane-enclosed
particles
secreted
by
diverse
cell
types,
including
exosomes,
microvesicles,
apoptotic
vesicles,
recently
identified
migrasomes.
These
can
be
taken
up
recipient
cells,
thereby
modulating
their
function
through
transport
cargo
molecules.
EVs
facilitate
intercellular
communication
play
significant
role
development
fibrosis.
Moreover,
detection
body
fluids
offers
sensitive
diagnostic
tools
for
assessing
Additionally,
may
serve
as
therapeutic
targets,
potential
agents,
drug
delivery
vehicles.
This
article
reviews
recent
advances
field
concerning
related
diseases,
with
particular
focus
on
newly
discovered
migrasomes
intracellular
crosstalk
within
liver.
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1493 - 1493
Published: Dec. 6, 2024
Extracellular
vesicles
(EVs)
are
small,
membrane-bound
particles
secreted
by
cells
into
the
extracellular
environment,
playing
an
increasingly
recognized
role
in
inter-organ
communication
and
regulation
of
various
physiological
processes.
Regarding
redox
homeostasis
context,
EVs
play
a
pivotal
propagating
mitigating
oxidative
stress
signals
across
different
organs.
Cells
under
release
containing
signaling
molecules
that
can
influence
status
distant
tissues.
starting
to
be
as
contributors
brain-liver
communication.
Therefore,
this
review,
we
show
how
imbalance
affect
brain
liver.
We
propose
mediators
axis.