Role of systemic inflammation response index and prognostic nutritional index in the prediction of moderate-to-severe bronchopulmonary dysplasia in very preterm infants DOI Open Access
Ning An, Jing Li, Mingxia Li

et al.

Translational Pediatrics, Journal Year: 2025, Volume and Issue: 14(1), P. 52 - 60

Published: Jan. 1, 2025

Bronchopulmonary dysplasia (BPD) is a severe chronic lung disease that primarily affects premature infants. BPD usually comes with delayed diagnosis, and the injury at time of confirmed diagnosis irreversible. The inflammatory response crucial pathogenic factor for BPD. combination prognostic nutritional index (PNI) systemic inflammation (SIRI) comprehensive indicator can reflect balance between immune status host response. This study aimed to explore predictive ability SIRI PNI moderate-to-severe (msBPD) in research involved infants born before 32 weeks gestational age (GA). division patients resulted two groups: control group no or mild msBPD group. Relevant data were collected compare differences regarding clinical data; calculated within 24 hours after birth [at 36 postmenstrual (PMA)]. predict was evaluated by logistic regression analysis. A total 491 included study, 435 56 exhibited lower levels higher compared area under curve (AUC) value [95% confidence interval (CI): 0.599 (0.514-0.685) 0.588 (0.504-0.672)], cut-off values >1.927 <34.105, respectively, birth. AUC 0.602 (0.515-0.689) 0.647 (0.569-0.725), >5.175 <45.080, PMA. have certain diagnostic managing

Language: Английский

Role of systemic inflammation response index and prognostic nutritional index in the prediction of moderate-to-severe bronchopulmonary dysplasia in very preterm infants DOI Open Access
Ning An, Jing Li, Mingxia Li

et al.

Translational Pediatrics, Journal Year: 2025, Volume and Issue: 14(1), P. 52 - 60

Published: Jan. 1, 2025

Bronchopulmonary dysplasia (BPD) is a severe chronic lung disease that primarily affects premature infants. BPD usually comes with delayed diagnosis, and the injury at time of confirmed diagnosis irreversible. The inflammatory response crucial pathogenic factor for BPD. combination prognostic nutritional index (PNI) systemic inflammation (SIRI) comprehensive indicator can reflect balance between immune status host response. This study aimed to explore predictive ability SIRI PNI moderate-to-severe (msBPD) in research involved infants born before 32 weeks gestational age (GA). division patients resulted two groups: control group no or mild msBPD group. Relevant data were collected compare differences regarding clinical data; calculated within 24 hours after birth [at 36 postmenstrual (PMA)]. predict was evaluated by logistic regression analysis. A total 491 included study, 435 56 exhibited lower levels higher compared area under curve (AUC) value [95% confidence interval (CI): 0.599 (0.514-0.685) 0.588 (0.504-0.672)], cut-off values >1.927 <34.105, respectively, birth. AUC 0.602 (0.515-0.689) 0.647 (0.569-0.725), >5.175 <45.080, PMA. have certain diagnostic managing

Language: Английский

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