Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk DOI Creative Commons
Alana A. Arnone, Yu-Ting Tsai,

J. Mark Cline

et al.

Cell Reports Medicine, Journal Year: 2024, Volume and Issue: unknown, P. 101880 - 101880

Published: Dec. 1, 2024

Language: Английский

The Microbiome: A New Frontier in Overcoming Drug Resistance in Breast Cancer DOI
Thifhelimbilu Emmanuel Luvhengo, Thabiso Victor Miya,

Afra Basera

et al.

Published: Jan. 1, 2024

The gut microbiome comprises bacteria, fungi, viruses, archaea, and their genetic materials. influences the physiological immunological functions of body. When there is a change in composition microbiota gut, this called dysbiosis. Dysbiosis linked with several gastrointestinal extra-gastrointestinal diseases, including some cases breast cancer (BC). Molecular Subtype stage diagnosis both affect way patients BC are managed. heterogeneous disease and, cases, response to treatment may not be as predicted. influence progression its treatment. Furthermore, also alter microbiota, leading This chapter reviews relationship between dysbiosis BC. how can manipulated improve tumor or reverse resistance drug elaborated on.

Language: Английский

Citations

0
Integrated analysis of microbiota and gut microbial metabolites in blood for breast cancer DOI Creative Commons
Peng Yu,

Jiale Gu,

Fubin Liu

et al.

mSystems, Journal Year: 2024, Volume and Issue: 9(11)

Published: Oct. 18, 2024

ABSTRACT Gut microbiota and associated metabolites have been linked to breast carcinogenesis. Evidences demonstrate blood primarily originates from the gut may act as a biomarker for cancer. We aimed characterize microbiota–gut microbial cross-talk in develop composite diagnostic panel performed 16S rRNA gene sequencing metabolomics profiling on samples 107 cancer cases age-paired controls. found that alpha diversity of was decreased compared There were significantly different profiles between these two groups, with nine bacterial genera four increased patients, while thirty-nine Some cancer-associated differential microbiota, microbiota–metabolite further developed an area under curve 0.963 This study underscored pivotal role their interactions carcinogenesis, well potential non-invasive IMPORTANCE Our integrated analysis demonstrated altered patients. The extensive correlation assisted understanding pathogenesis good performance suggested approach detection novel strategy better diagnosis prevention future.

Language: Английский

Citations

0
Investigating the Role of the Intratumoral Microbiome in Thyroid Cancer Development and Progression DOI

Hanieh Ataollahi,

Mehdi Hedayati, Noosha Zia-Jahromi

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2024, Volume and Issue: unknown, P. 104545 - 104545

Published: Oct. 1, 2024

Language: Английский

Citations

0
Antitumor potentials of onco-microbial in Chinese patients with pancreatic cancer DOI Creative Commons
Yongchao Gao,

Dingding Zhou,

Yebin Lu

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(24), P. e40890 - e40890

Published: Dec. 1, 2024

Language: Английский

Citations

0
Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk DOI Creative Commons
Alana A. Arnone, Yu-Ting Tsai,

J. Mark Cline

et al.

Cell Reports Medicine, Journal Year: 2024, Volume and Issue: unknown, P. 101880 - 101880

Published: Dec. 1, 2024

Language: Английский

Citations

0