The role of the sulfaguanidine molecular scaffold in drug design and development

Archiv der Pharmazie, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

Abstract Developing new molecular entities is one of the most emerging research areas in field Medicinal Chemistry. Over past few years, rigorous has been conducted on sulfaguanidine‐linked synthetic molecules because their promising potential several biological activities. Sulfaguanidine actively incorporated design anticancer, antimicrobial, antidiabetic, antiparkinsonian, anti‐inflammatory, and antiviral candidates. The construction these effective candidates adopted many chemical approaches. A number prepared compounds displayed results that merit further investigations for development medications. This review summarizes different strategies reported activities throughout 2020–2024.

Language: Английский

Synthesis and antitumor activity of new series of isopimaric heterocyclic sulfonamides derivatives

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 224, P. 120300 - 120300

Published: Dec. 14, 2024

Language: Английский