Deciphering the Gut–Liver Axis: A Comprehensive Scientific Review of Non-Alcoholic Fatty Liver Disease DOI Creative Commons
Samradhi Singh, Mona Kriti, Roberto Catanzaro

et al.

Livers, Journal Year: 2024, Volume and Issue: 4(3), P. 435 - 454

Published: Sept. 12, 2024

Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant global health issue. The condition is closely linked to metabolic dysfunctions such obesity and type 2 diabetes. gut–liver axis, bidirectional communication pathway between the gut, plays crucial role in pathogenesis of NAFLD. This review delves into mechanisms underlying exploring influence gut microbiota, intestinal permeability, inflammatory pathways. also explores potential therapeutic strategies centered on modulating microbiota fecal transplantation; phage therapy; use specific probiotics, prebiotics, postbiotics managing By understanding these interactions, we can better comprehend development advancement NAFLD identify targets.

Language: Английский

Unveiling Current and Future Trends in the Implementation of Teaching Games for Understanding in Primary School: A Bibliometric Analysis DOI Creative Commons
Irfan Oktavianus, Uray Gustian, Andika Triansyah

et al.

Physical Education Theory and Methodology, Journal Year: 2025, Volume and Issue: 25(1), P. 191 - 201

Published: Jan. 30, 2025

Background. Physical Education (PE) often focuses on sports skills through command-based teaching methods, which can lead to students struggling understand and effectively play games. To address this issue, Teaching Games for Understanding (TGfU) has been introduced as a more effective approach enhance tactical comprehension gameplay skills, while also increasing student engagement in physical activities. Objectives. This study aimed identify current research trends future potential TGfU implementation elementary school PE bibliometric analysis. Materials methods. A was used by analyzing 977 documents from the Scopus database published between 2015 2024. The data analyzed using VOSviewer map bibliographic networks conduct keyword science mapping applied emerging predict of implementation. Results. analysis revealed that improves activity, motor well-being students. However, further is needed fully validate these findings.Current emphasize importance enhancing approach. Future point towards developing curricula undersore integrated use holistic approaches. Conclusions. Implementing schools holds great improving engagement, skill development, students’ psychological well-being. Challenges include optimizing role teachers facilitators adapting curriculum broader application. Further required application model develop approaches relevant needs

Language: Английский

Citations

0
Deciphering the Gut–Liver Axis: A Comprehensive Scientific Review of Non-Alcoholic Fatty Liver Disease DOI Creative Commons
Samradhi Singh, Mona Kriti, Roberto Catanzaro

et al.

Livers, Journal Year: 2024, Volume and Issue: 4(3), P. 435 - 454

Published: Sept. 12, 2024

Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant global health issue. The condition is closely linked to metabolic dysfunctions such obesity and type 2 diabetes. gut–liver axis, bidirectional communication pathway between the gut, plays crucial role in pathogenesis of NAFLD. This review delves into mechanisms underlying exploring influence gut microbiota, intestinal permeability, inflammatory pathways. also explores potential therapeutic strategies centered on modulating microbiota fecal transplantation; phage therapy; use specific probiotics, prebiotics, postbiotics managing By understanding these interactions, we can better comprehend development advancement NAFLD identify targets.

Language: Английский

Citations

0