Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 24, 2025

Evaluation of Cardiovascular diseases (CVDs), the leading cause death worldwide, and their risk factors is critical for developing effective healthcare interventions, especially in countries like Iran, where economic demographic challenges may impact outcomes. This study aimed to evaluate temporal trends burden CVDs a country Middle East, using Global Burden Disease (GBD) 2021. The data from GBD 2021 was used extraction, processing, presentation results. Deaths, disability-adjusted life years (DALYs), lost (YLLs), lived with disability (YLDs) attributable all factors, addition metabolic, behavioral, environmental/occupation were reported Iran 1990 All metrics as point estimates 95% uncertainty intervals (UIs). From 2021, total number deaths DALYs attributed increased by 99.28% (95% UI 85.93-112.36%) 65.85% (55.88 77.01), respectively. However, age-standardized rates decreased significantly 43.16% (- 46.34% - 39.97%) 45.82% 48.82 42.71), Metabolic contributors (189.98 [166.38 209.83] 3575.8 [3206.1 3928.27], respectively), high systolic blood pressure (SBP) accounting highest burden. Males, particularly older age groups (≥ 80 years), experienced higher compared females. Although there no clear relationship between provinces' sociodemographic index (SDI) regions SDIs tend have lower disease. Our findings indicate that while decreased, still faces significant associated factors. In this regard, SBP needs special attention. These highlight urgent need subnational, risk-specific policies targeting high-risk populations low-SDI provinces reduce disparities CVD Immediate targeted interventions are necessary disparities, costs, address these

Language: Английский