The role of dorsal premotor cortex in joint action inhibition DOI Creative Commons

Elisa Dolfini,

Pasquale Cardellicchio, Luciano Fadiga

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 26, 2024

Behavioral interpersonal coordination requires smooth negotiation of actions in time and space (joint action-JA). Inhibitory control may play a role fine-tuning appropriate coordinative responses. To date, little research has been conducted on motor inhibition during JA the modulatory influence that premotor areas might exert inhibitory control. Here, we used an interactive task which subjects were required to reach open bottle using one hand. The was held stabilized by co-actor (JA) or mechanical holder (vice clamp, no-JA). We recorded two TMS-based indices (short-interval intracortical inhibition-sICI; cortical silent period-cSP) reaching phase task. These reflect fast (GABAa-mediated) slow corticospinal (GABAb-mediated) inhibition. Offline continuous theta burst stimulation (cTBS) interfere with dorsal cortex (PMd), ventral (PMv), site (vertex) before execution Our results confirm dissociation between provide evidence drive only mechanisms, turn behavioral co-adaptation trials. Exploratory analyses further suggest PMd, more than PMv, is key source sculpting movements, according socio-interactive context.

Language: Английский

Effective Autism Classification Through Grasping Kinematics DOI Creative Commons
Erez Freud, Zoha Ahmad, Eitan Shelef

et al.

Autism Research, Journal Year: 2025, Volume and Issue: unknown

Published: May 5, 2025

ABSTRACT Autism is a complex neurodevelopmental condition, where motor abnormalities play central role alongside social and communication difficulties. These symptoms often manifest in early childhood, making them critical targets for diagnosis intervention. This study aimed to assess whether kinematic features from naturalistic grasping task could accurately distinguish autistic participants non‐autistic ones. We analyzed movements of young adults, tracking two markers placed on the thumb index finger. Using subject‐wise cross‐validated classifiers, we achieved accuracy scores above 84%. Receiver operating characteristic analysis revealed strong classification performance with area under curve values 0.95 at 0.85 trial‐wise analysis. findings indicate reliability distinguishing suggest that subtle control differences can be effectively captured, offering promising approach developing accessible reliable diagnostic tools autism.

Language: Английский

Citations

0
Decreased central corpus callosum volume in autistic children is associated with repetitive behaviours and motor skills DOI

Gaia Scaccabarozzi,

Denis Peruzzo, Filippo Arrigoni

et al.

Published: May 16, 2025

Language: Английский

Citations

0
The role of dorsal premotor cortex in joint action inhibition DOI Creative Commons

Elisa Dolfini,

Pasquale Cardellicchio, Luciano Fadiga

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 26, 2024

Behavioral interpersonal coordination requires smooth negotiation of actions in time and space (joint action-JA). Inhibitory control may play a role fine-tuning appropriate coordinative responses. To date, little research has been conducted on motor inhibition during JA the modulatory influence that premotor areas might exert inhibitory control. Here, we used an interactive task which subjects were required to reach open bottle using one hand. The was held stabilized by co-actor (JA) or mechanical holder (vice clamp, no-JA). We recorded two TMS-based indices (short-interval intracortical inhibition-sICI; cortical silent period-cSP) reaching phase task. These reflect fast (GABAa-mediated) slow corticospinal (GABAb-mediated) inhibition. Offline continuous theta burst stimulation (cTBS) interfere with dorsal cortex (PMd), ventral (PMv), site (vertex) before execution Our results confirm dissociation between provide evidence drive only mechanisms, turn behavioral co-adaptation trials. Exploratory analyses further suggest PMd, more than PMv, is key source sculpting movements, according socio-interactive context.

Language: Английский

Citations

2