Research Progress of Mesenchymal Stem Cell Engineering Modification Strategies in Stem Cell-Based Therapy

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(01), P. 2286 - 2296

Published: Jan. 1, 2025

Language: Английский

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Skin regenerative potential of hydrogel matrices incorporated with stem cell-derived extracellular vesicles enriched with MicroRNAs: a systematic review

Molecular and Cellular Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Language: Английский

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Mesenchymal stem cell therapy for ischemic cardiomyopathy: Research progress and prospects for application

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: April 10, 2025

This review aims to explore the research progress and application prospects of mesenchymal stem cells (MSCs) in treatment ischemic cardiomyopathy (ICM). ICM is a severe heart disease characterized by death myocardial due long-term ischemia, leading impaired function. MSCs have become one promising therapeutic methods for treating their unique anti-inflammatory, anti-apoptotic, immunomodulatory, pro-angiogenic properties. Studies shown that can improve function promoting neovascularization, reducing cell apoptosis, inhibiting inflammatory responses, regulating immune reactions. Additionally, be sourced from various tissues, including bone marrow, adipose tissue, umbilical cord/placenta, with different sources possessing distinct characteristics effects. Clinical studies indicated MSC therapy physical capacity left ventricular ejection fraction (LVEF) patients intractable angina, enhance perfusion overall infarction. However, issues such as mechanisms MSCs, optimal source, infusion routes, dose optimization still require further research. Future need address these transform clinical trials routine practice, thereby revolutionizing management prognosis ICM.

Language: Английский

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Fabrication of polydopamine-altered PCL/PLGA nanofibrous scaffolds on cerium to enhance cytocompatibility, microbial inhibition, and improved osteogenic properties for tissue regeneration in orofacial treatment

Biochemical and Biophysical Research Communications, Journal Year: 2025, Volume and Issue: 766, P. 151852 - 151852

Published: April 18, 2025

Language: Английский

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Stimuli-responsive carrageenan-based biomaterials for biomedical applications

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138920 - 138920

Published: Dec. 1, 2024

Language: Английский

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