Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown
Published: May 1, 2025
Language: Английский
Animals, Journal Year: 2024, Volume and Issue: 14(4), P. 627 - 627
Published: Feb. 16, 2024
Despite significant advances in vaccination strategies and antibiotic therapy, bovine respiratory disease (BRD) continues to be the leading affecting global cattle industry. The etiology of BRD is complex, often involving multiple microbial agents, which lead intricate interactions between host immune system pathogens during various beef production stages. These present environmental, social, geographical challenges. Accurate diagnosis essential for effective management. Nevertheless, correct identification cases remains a daunting challenge animal health technicians feedlots. In response current regulations, there growing interest refining clinical diagnoses curb overuse antimicrobials. This shift marks pivotal first step toward establishing structured diagnostic framework this disease. review article provides an update on recent developments future perspectives diagnostics prognostic techniques BRD, assessing their benefits limitations. methods discussed include evaluation signs behavior, biomarker analysis, molecular diagnostics, ultrasound imaging, modeling. While some show promise as standalone it likely that multifaceted approach-leveraging combination these methods-will yield most accurate BRD.
Language: Английский
Citations
21
Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11
Published: June 15, 2023
This paper estimates the effect of antibiotic usage in humans and food-producing animals on prevalence resistance zoonotic bacteria both animals. Using comprehensive longitudinal data from annual surveillance reports Europe, we find that are independently causally related to The study considers simultaneous total antibiotics identify marginal effects joint groups. By employing lagged-dependent variable fixed-effects specifications, provide a lower an upper bound resistance. also contributes scant literature how use is other
Language: Английский
Citations
25
Veterinary Medicine Research and Reports, Journal Year: 2024, Volume and Issue: Volume 15, P. 1 - 14
Published: Jan. 1, 2024
Abstract: Dairy farming faces a significant challenge of bacterial infections in dairy calves, which can have detrimental effects on their health and productivity. This review offers comprehensive overview the most prevalent including Escherichia coli, Salmonella typhimurium, dublin, enterica, Clostridium perfringens, Pasteurella multocida, Listeria monocytogenes, Mycoplasma bovis , Haemophilus somnus . These pathogens cause various clinical signs symptoms, leading to diarrhea, respiratory distress, septicemia, even mortality. Factors such as management practices, environmental conditions, herd influence incidence severity infections. Efficient prevention strategies include good colostrum nutrient feeding, early detection, appropriate treatment, hygiene supportive care. Regular monitoring diagnostic tests facilitate detection intervention. The use antibiotics should be judicious prevent antimicrobial resistance care fluid therapy nutritional support promotes recovery. Diagnostic methods, immunological tests, culture, polymerase chain reaction (PCR), serology, aid identification specific pathogens. also explores recent advancements diagnosis, providing valuable insights for farmers, veterinarians, researchers. By synthesizing pertinent scientific literature, this contributes development effective aimed at mitigating impact health, welfare, productivity young calves. Moreover, more research is required enhance understanding epidemiology characterization Keywords: bacteria, pneumonia, vaccination, calve
Language: Английский
Citations
11
Microbial Pathogenesis, Journal Year: 2024, Volume and Issue: 187, P. 106533 - 106533
Published: Jan. 1, 2024
Language: Английский
Citations
10
Journal of Dairy Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
2
Viruses, Journal Year: 2023, Volume and Issue: 15(3), P. 669 - 669
Published: March 2, 2023
Bovine respiratory diseases (BRD) are associated with various predisposing factors, such as physical and physiological stress bacterial viral pathogens. These stressors viruses suppress immune defenses, leading to growth in the upper tract invasion of pathogens into lower tract. Therefore, continuous monitoring causative would contribute early detection BRD. Nasal swabs sera from 63 clinically healthy calves were continuously collected seven farms Iwate prefecture 2019 2021. We attempted monitor dynamics BRD-associated by multiplex real-time RT-PCR (RT-qPCR) using their nasal swab samples. In addition, we fluctuation antibody titers against each pathogen virus neutralization test (VNT) sera. contrast, 89 infected BRD 28 analyze samples RT-qPCR aim detect that dominant this region. As a result, our analyses showed positive results closely related significant increase VNT bovine coronavirus (BCoV), torovirus (BToV), syncytial (BRSV). data exhibited BCoV, BToV, BRSV, parainfluenza 3, Mycoplasma bovis have been more frequently detected compared those calves. Moreover, presented herein revealed co-infections combination multiple involved onset Taken together, study demonstrates which can simultaneously pathogens, including bacteria, is useful for
Language: Английский
Citations
16
Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11
Published: Feb. 23, 2024
Despite the fact that pneumonia remains a leading cause of mortality and morbidity in pre-weaned calves, relatively little is known regarding effects concurrent administration intranasal virus vaccines, particularly calves with high levels maternally derived antibodies. The objective this study was to use cohort 40 dairy dairy-beef female male (27 females 13 males) determine serological responses at 3 weeks age (22 ± 4.85 days) two commercially available (IN) vaccines for viruses: bovine respiratory syncytial (BRSV), herpes 1 (BoHV-1), parainfluenza-3-virus (PI3-V). groups were as follows: (i) Bovilis IBR Marker Live only® (IO), (ii) INtranasal RSP Live® only (RPO), (iii) Concurrent vaccination & Intranasal (CV), (iv) control group non-vaccinated (CONT). calves’ response post-IN vaccination, clinical health scores, rectal temperatures, weights measured. Data analyzed SAS using mixed models logistic regression. CV had an average daily weight gain (ADG) 0.74 (±0.02) kg, which similar CONT (0.77 0.02 kg). no significant differences antibody between following subsequent parenteral injections form Bovipast RSP®(antigens; inactivated BRSV, PI3-V, Mannheimia haemolytica ) Live®, BRSV PI3-V increased both RPO groups. resulted increase fever difference scores when compared CONT.
Language: Английский
Citations
5
Brazilian Journal of Microbiology, Journal Year: 2023, Volume and Issue: 54(2), P. 1169 - 1179
Published: Feb. 10, 2023
Language: Английский
Citations
10
Animals, Journal Year: 2024, Volume and Issue: 14(9), P. 1256 - 1256
Published: April 23, 2024
This study aims to determine the serological profile of high-yielding dairy cows for four main viruses (bovine alphaherpesvirus 1 (BoAHV1), bovine viral diarrhea virus (BVDV), parainfluenza 3 (BPIV3), and respiratory syncytial (BRSV)) related disease (BRD) in cattle herds worldwide. In this survey, 497 blood serum samples were collected from non-vaccinated without clinical signs 39 central-eastern mesoregion Paraná State, South Brazil. The presence neutralizing antibodies was determined by neutralization (VN) tests. VN against BoAHV1, BVDV, BPIV3, BRSV detected 355 (71.4%), 280 (56.3%), 481 (96.8%), 315 (63.4%) samples, respectively. frequencies seropositive 79.5 (n = 31), 82.0 32), 100 39), 84.6% 33), varied according type herd management number herd. detection unvaccinated demonstrated endemic circulation evaluated. For BRD prevention, it is recommended implement a vaccination program that provides passive immunity calves active cows.
Language: Английский
Citations
4
Future Microbiology, Journal Year: 2024, Volume and Issue: 19(10), P. 903 - 929
Published: April 25, 2024
Antibiotics' action, once a 'magic bullet', is now hindered by widespread microbial resistance, creating global antimicrobial resistance (AMR) crisis. A primary driver of AMR the selective pressure from use. Between 2000 and 2015, antibiotic consumption increased 65%, reaching 34.8 billion tons, 73% which was used in animals. In dairy cattle sector, antibiotics are crucial for treating diseases like mastitis, posing risks to humans, animals potentially leading environmental contamination. To address AMR, strategies dry cow therapy, alternative treatments (nanoparticles, phages) waste management innovations emerging. However, most solutions development, emphasizing urgent need further research tackle farms.
Language: Английский
Citations
4