Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107516 - 107516
Published: March 1, 2025
Language: Английский
Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107516 - 107516
Published: March 1, 2025
Language: Английский
ACS Sustainable Chemistry & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 9, 2025
The inefficient application and ineffective delivery of nematicides on agriculture have caused serious waste pesticides environmental pollution. It is urgent to develop new carriers for that are long-acting environmentally friendly. In this study, biodegradable cellulose acetate was used as the carrier material prepare two kinds fluopyram (Flp)-loaded nanofibers by coaxial electrospinning (CA-CE@Flp) uniaxial (CA-UE@Flp), respectively. During preparation Flp-loaded nanofibers, we deposited them root plant. 45-day pot experiment, root-protective films would release Flp protect from Meloidogyne incognita infection. control effects CA-UE@Flp CA-CE@Flp 80% 64%. distribution around rhizosphere soil, with sustainable property performed more uniform Flp, which led long-term effect against M. plant safety. high efficiency can achieve short-term disease prevention control. novel nanofiber precision developed provides a strategy green, safe, efficient shows great potential fiber products protection.
Language: Английский
Citations
0Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 125909 - 125909
Published: Feb. 1, 2025
Language: Английский
Citations
0International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 2865 - 2865
Published: March 21, 2025
The growing demand for agricultural products has led to the misuse of pesticides, resulting in use higher concentrations these substances. This an increase toxicity imposed on other beneficial organisms and bioaccumulation toxic pesticide bodies both pests non-target organisms, as well their end users, including humans. In this study, neurotoxic potential commonly used pesticides abamectin (an insecticide) boscalid (a fungicide) was evaluated. Both vitro silico studies showed that human butyrylcholinesterase is not a target abamectins B1A B1B. Boscalid modest Glide score (−28.8 kJ/mol) considerably IC50 (308.8 µM) against than approved inhibitor (2-((1-(benzenesulfonyl)-1H-indol-4-yl)oxy)ethyl)(benzyl)amine (IC50 = 0.473 µM). However, due its non-mutagenicity low toxicity, structural analogues might be considered candidates symptomatic treatment Alzheimer’s disease. Molecular dynamics simulations over 100 ns confirmed stability within active site butyrylcholinesterase, where it maintained key interactions with catalytic residues such Trp82 His438. These findings highlight starting point structure-based drug design strategies aimed at optimizing cholinesterase inhibitors improved pharmacokinetic properties. According absorption, distribution, metabolism, elimination, studies, orally active, which cannot attributed
Language: Английский
Citations
0Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107516 - 107516
Published: March 1, 2025
Language: Английский
Citations
0