Bohn Stafleu van Loghum eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 701 - 704
Published: Nov. 13, 2023
American Journal of Clinical Dermatology, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 17, 2024
Neuropathic itch is a type of chronic pruritus resulting from neural dysfunction along the afferent pathway. It often accompanied by abnormal sensations such as paresthesia, hyperesthesia, or hypoesthesia. This condition, which may involve motor autonomic damage, significantly impacts patients' quality life, causing severe and associated comorbidities depression, disrupted sleep, social strain. accounts for 8% cases, though this be underestimated. comprehensive review focuses on nerve impingement primary pathophysiological mechanism various forms neuropathic including brachioradial (BRP), notalgia paresthetica (NP), anogenital itch. BRP, seen in middle-aged white women, manifests dorsolateral forearms typically exacerbated ultraviolet (UV) exposure related to cervical spine pathology. NP, prevalent presents upper back due thoracic compression. Anogenital pruritus, affecting 1-5% adults, linked lumbosacral issues after ruling out dermatologic conditions lichen sclerosus simplex chronicus. The pathophysiology involves both peripheral central mechanisms, with damage being key factor. Diagnosis requires thorough history, physical examination, potentially imaging studies. Topical agents menthol, capsaicin, lidocaine are used mild while systemic medications gabapentin, pregabalin, antidepressants prescribed moderate cases; however, no US Food Drug Administration (FDA)-approved therapies currently exist specifically Understanding underlying appropriate therapeutic strategies crucial managing effectively.
Language: Английский
Citations
2
World Journal of Gastrointestinal Endoscopy, Journal Year: 2024, Volume and Issue: 16(3), P. 112 - 116
Published: March 14, 2024
Anal pruritus is a common anorectal symptom that can significantly impair patient's quality of life, including their mental health. It be one the most difficult proctological conditions to treat. Patients often delay seeking medical attention, since it an embarrassing but non-life-threatening situation. Pruritus ani associated with idiopathic and secondary causes, such as diseases, cancer (anal or colorectal), dermatological sexually transmitted fungal infections systemic diseases. If patients are referred for colonoscopy, this sometimes provide first opportunity evaluate perianal area. Classifications anal based on abnormalities skin, commonly used being Washington classification. A proper digital examination important, well anoscopy help exclude diseases suspicious masses. Endoscopists should aware etiologies, classification area provided in colonoscopy report. Information treatment possibilities follow-up also provided. The normally consists triple approach: hygiene, elimination irritants, skin care protection. Several topical therapies have been described possible treatments, steroids, capsaicin, tacrolimus methylene blue intradermal injections.
Language: Английский
Citations
1
Schweizer Gastroenterologie, Journal Year: 2024, Volume and Issue: 5(2), P. 53 - 58
Published: June 11, 2024
Abstract Anal pruritus is a frequent disorder accounting for many proctological consultations, affecting mainly middle-aged males. It believed that it implies vicious circle of itching and scratching, increasing irritation inflammation, thus symptoms. The most causes are irritant factors such as anal over-hygiene some foods, faecal soiling due to incontinence, diseases haemorrhoids. Candida infections the anus dermatological including contact dermatitis also frequent. Treatment depends principally on underlying aetiology.
Language: Английский
Citations
0
Journal of Dermatological Treatment, Journal Year: 2024, Volume and Issue: 35(1)
Published: June 13, 2024
Pruritus is an unpleasant sensation that creates the urge to scratch. In many chronic conditions, relentless pruritus and scratching perpetuates a vicious itch-scratch cycle. Uncontrolled itch can detrimentally affect quality of life may lead sleep disturbance, impaired concentration, financial burden, psychological suffering. Recent strides have been made develop guidelines investigate new therapies treat some most common severely pruritic however, large group diseases remains underrecognized undertreated. The purpose this article provide comprehensive review challenges hindering treatment pruritus.
Language: Английский
Citations
0
Published: Jan. 1, 2024
Citations
0
Ambulatornaya khirurgiya = Ambulatory Surgery (Russia), Journal Year: 2024, Volume and Issue: 21(1), P. 100 - 104
Published: May 17, 2024
Introduction. Anal contact or conduction in the anal canal and rectum is a common condition coloproctological field, occurring 5% of population that affects this country. Treatment consists hygiene use topical steroids, antibacterial antifungal agents. No generally accepted attitude towards private person has been developed. Aim . To study effectiveness using homeopathic ointment treatment patients with itching. Material methods A prospective comparative randomized was conducted specialized advisory center Clinics Samara State Medical University. The included 96 itching without fungal infection perianal skin concomitant purulent pathology. In main group (n = 46), carried out area 2–3 times day for 14 days. control 50), steroid ointments Results discussion From data obtained on ointment, it follows not inferior to reducing symptoms disease (Student’s t-test 0.35; p > 0.05 Student’s 0.28; 0.05), by number relapses (χ 2 0.535; 0.05). Conclusion. application appears be promising new as effective ointments.
Language: Английский
Citations
0
Bohn Stafleu van Loghum eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 701 - 704
Published: Nov. 13, 2023
Citations
0